VRU 2007 Flashcards
What are the top breeds for skeletal histiocytic sarcoma? And age?
Goldens
Rotties
Over 5 years of age
History of lameness or neurologic deficits
Where does skeletal histiocytic sarcoma like to be located?
Periarticular - most common!
Vertebral
Proximal humerus - Differential for primary bone tumor
Most skeletal histiocytic sarcomas have what associated with the bony destruction?
Soft tissue mass
Periarticular histiocytic sarcoma likely involves multiple periarticular bones or just one?
Multiple. It is likely the histiocytes come from the synovium.
What two characteristics are associated with diseeminated histiocytic sarcoma disease?
- Rotties - All rotties had disseminated disease
- Bony involvement.
Disseminated is multiple organs while local is one organ with LN involvement.
Rose et al: Standing myelogram in horse: What contrast was used?
iohexol - non-ionic Monomer
Rose et al: Standing myelogram in horse: Why did the other advise against a cervical approach?
Lack of consistently good flow.
What should be the cutoff days for letting cats go (in days) be after I131 treatment due to Surface containation (from licking (saliva) and urination).
7 days
Marolf et al: Tracheal collapse and bronchiectasis in dogs: How much more times are dogs with tracheal collapse likely to have bronchiectasis?
6x more likely.
Marolf et al: Tracheal collapse and bronchiectasis in dogs: Why are dogs with tracheal collapse predisposed to bronchiectasis?
Tracheal collapse is related to chronic inflammation and mucosal congestion hindering the mucociliary clearance
Marolf et al: Tracheal collapse and bronchiectasis in dogs: What percentage of dogs had bronchiectasis in just one lobe vs multiple? which lobe was most affected?
50/50 with the cranial lung lobes being most affected.
Kinns et al: Malignant LN and US hetterogeneity: What was the percentage of heterogeneous LN that were malignant in dogs and cats, and was this significant?
Dogs: 91% of heterogenous LN were malignant - Yes significance
Cats: 63% of heter LN were malignant - NO significance - LIKELY do to most of cat neoplasia is lymphoma
Martinez et al: Hypoechoic renal subcapsular thickening and lymphoma in cats: What was the PPV, NPV sensitivity and specificity of renal hypoechoic subcapsular thickening being lymphosarcoma?
PPV: 81%
NPV: 67%
Sensitivity: 61%
Specificity: 85%
This means that if you have it it is likely lymphoma… if you don’t have it…still could be lymphoma!
Martinez et al: Hypoechoic renal subcapsular thickening and lymphoma in cats: Renal lymphoma represents what percentage of all lymphomas in cats?
5-20%
Martinez et al: Hypoechoic renal subcapsular thickening and lymphoma in cats: What was the most common appearance? Crescent shaped or rim-like?
Crescent shaped.
Martinez et al: Hypoechoic renal subcapsular thickening and lymphoma in cats: Uncommon differentials for this finding?
Different types of neoplasia
Chronic active nephritis from FIP.
Ohlerth et al: Contrast harmonic normal dog spleen: What was the peak intensity and time to peak enhancement?
- 6dB
- 6s
Ohlerth et al: Contrast harmonic normal dog spleen: Was there a significant difference between weight groups in peak intensity, time to peak or AUC?
No.. no associatation found with CBC differences, blood pressure, HR, age, gender… NOTHING.
Cole et al: CECT auditory tube: Explain the procedure?
Dog in lateral recumbency
Myringotomy was made
Contrast infused into the ear canal and middle ear with a balloon-tip catheter (1:1 ratio of water to Contrast)
Contrast ear canalography with 1:1 iohexol showed what type of adverse reactions?
NONE: but they flushed after.
Iseri et al: Pancreatic CECT in dogs: What was the normal arterial and pancreatic times for enhancement? What was the normal enhancement values of the pancreas?
15s arterial
28s pancreatic
118+/- 16 HU for pancreas.
Iseri et al: Pancreatic CECT in dogs: when was the highest difference between the insulinoma HU and normal pancreatic HU?
The arterial phase!
What is the most common canine pancreatic endocrine tumor?
Insulinoma.
Van der et al: Dynamic CT for Pituitary gland: What is the best protocol for pituitary gland scanning?
1 mm slices
pitch of 2.
Differentiates neuro from adenohypophysis.
Thomason et al: Changes in dorasl acetabular ridge and rotation of hips; Ventral rotation will cause the acetabulum to look smaller or larger?
Smaller
O’Brien: Detection of hepatic hemangio mets CEUS; What were the appearance of the nodules after CE?
Hypoechoic — lack of normal blood architechture.
Hecht et al: Pancreatic neoplasia and nodular hyperplasia cats; What was the only unique imaging finding in malignant pancreatic tumors?
Single pancreatic nodule
Mass exceeding 2 cm
Nodular hyperplasia had lymphadenopathy, abdominal effusion, and mass effect on rads.
Hecht et al: Pancreatic neoplasia and nodular hyperplasia cats; What was the most common radiographic finding of pancreatic nodular hyperplasia? Neoplasia?
Mass effect. - nodular hyperplasia
Mass effect and abdominal effusion - neoplasia
Can US and rads replace cytology when dealing with neoplasia vs nodular hyperplasia of the pancreas in a cat?
NO
Kneissl et al: MRI features of orital inflammation: What canals were used for intracranial extension? Which one was most common?
Optic canal
Orbital fissure — most common
Alar canal
Kneissl et al: MRI features of orital inflammation: What sequences were most helpful?
Transverse- T2
Dorsal - STIR
Trans or dorsal - Post contrast
Holloway et al: Perirenal effusion in dogs and cats with AKI: Was the volume of the perirenal fluid associated with severity of renal dysfunction?
No.
Holloway et al: Perirenal effusion in dogs and cats with AKI: How is perirenal fluid developed?
Ultrafiltrate that backs up into the renal interstitium from the tubules that then overwhelms the lymphatics
Holloway et al: Perirenal effusion in dogs and cats with AKI: Common renal changes associated with perirenal effusion?
Pyelectasia
Increase renal echogenicity
Change in size (mostly increased)
Ureteral or renal calculi.
Thoracic histiocytic sarcoma characteristics are?
Lymphadenopathy, pleural effusion.
Right middle lung lobe.
Cole et al: Transsplenic portal scintigraphy 99mTc -Mebrofenin: What was the time to peak liver activity and 1/2 life of hepatic excretion? Visulaization of defined biliary activity?
2-4min - Peak activity
6-11 min - biliary tree visualization
13-26min- 1/2 of hepatic excretion
Cole et al: Transsplenic portal scintigraphy 99mTc -Mebrofenin: Why could transit times not be calculated like with 99mTc - pertech?
Due to the large amount of hepatic extraction of mebrofenin.
What is the normal hepatic extraction efficiency of 99mtc-mebrofenin? What would be seen if hepatic failure?
>90%
Blood pooliing and cardiac activity. (lack of extraction)
Trasch et al: US of canine mastitis: What was the characteristics of infected mammary gland tissue?
Loss of distinct layering
Reuced echogenicity
Trasch et al: US of canine mastitis: What might be able to predict outcomes of mastitis?
Doppler - Reduced blood vessel density centrally
B-Mode was not able to do this.
H van et al: CT of the pituitary gland in healthy dogs; Which portion of the pituitary gland enhances first?
Neurohypophysis.. which is more caudal (posterior)
H van et al: CT of the pituitary gland in healthy dogs; Where does the neurohypophysis originate from and where does the adenohypophysis originated from?
Neurohypohysis = neuro diencephalon tissue
Adenohypophysis = roof of nasal cavity.
Seiler et al: CT features of skull osteomyelitis in dogs: Osteomyelitis was most commonly caused by what?
Trauma or bite wounds with Staph aureus being the most common pathogen.
Seiler et al: CT features of skull osteomyelitis in dogs: Where are the common sites for osteomyelitis and why?
Long bones and vertebrae of growing animals
Bacteria migrate to metaphyses and epiphyses where sluggish and turbulent blood flow in the venous sinusoids in the growing bone facilitates bacterial seeding.
Seiler et al: CT features of skull osteomyelitis in dogs: What are the radiographic appearances of osteomyelitis?
Multifocal bone lysis
Poorly defined margins
Sclerosis
Irregular periosteal reacion
Sequestra
Seiler et al: CT features of skull osteomyelitis in dogs: The features in this studyy were aggressive or subtle?
Very aggressive with extensive bone lysis, proliferation and soft tissue thickening.
Juvenile neoplasia: Osteosarc, lymphoma, Ewing’s Sarcoma are hard to destinugish
Osteomyeolitis is commonly more sclerosis and periosteal reaction and not lysis
Taeymans et al: US of hypothyroid dogs: What first presentation charactistics of the thyroid gland (if all 5 combined) gave a 94% sensitivity in detection of acquired hypothroidism?
Decreased echogenicity - 77% sensitive by itself
Inhomogeneity - 65%
Irregualr capsule delineation - 71%
Abnormal lobe shape - 65%
Decreased relative thyroid volume - 47%
Taeymans et al: US of hypothyroid dogs: What is the advocated cut-off for normal volume of a canine thyroid gland?
0.05ml/kg0.75
Schultz et al: MRI of Trigem disorders: What were the two histopath diagnosis?
Neuritis (2/6)
Nerve sheath tumor (4/6)