Vitamin C/Ascorbic Acid Flashcards
One hydrogen off of ascorbic acid is
ascorbate
Two hydrogens off of ascorbic acid is
dehydroascorbate
What are the transporters for Vit C
sodium dependent transporters 1 and 2 (SVCT1 and 2)
what destroys ascorbic acid
heat, oxidation, alkaline solutions
what are the functions of vitamin c
cofactor, antioxidant, hydroxilation, collagen synthesis, carnatine synthesis, tyrosine metabolism, neurotransmitter synthesis, proxidant, enhance immune function
what is the common interaction we see with Vitamin C
Vit C increases absorption of nonheme iron
In what way does Vitamin C influence Iron
Stabilizes from ferric (F3+) to Ferrous (F2+)
What are some excellent sources of vitamin C
red peppers, oranges, orange juice, kiwi, broccoli, strawberries, brussels sprouts
what are some good sources of vitamin c
spinach, green peas
where is Vitamin C absorpbed
in the small intestine, usually the proximal jejunum
what transporters are used to transport dehydroascorbic acid
GLUT 1 and 3
what happens to excess vitamin C
excreted in urin within 6 hrs
how to classify scurvy
total pool <300mg, plasma <0.2mg/dL
what are the four Hs of scurvy s/s
hemorrhagic, hyperkeratosis, hypochondriasis (neurological), and hematologic abnormalities
examples of deficiency s/s
fatigue, malaise, impaired wound healing, arthralgia,petechiae, corkscrew hair, swollen/bleeding gums
