Biotin Flashcards
when and who discovered biotin
1931, Szent Gyorgyi
when and who isolated biotin’s structure
1940 by Kogl and du Vigneaud
what are some excellent sources of biotin
beef liver, whole milk
what are some good sources of biotin
egg yolk, peanuts, canned salmon
what are some s/s of biotin deficiency
lethargy, paresthesias in extremities, depression, hallucinations, red/dry/scaly dermatitis in eyes, nose, and mouth, brittle nails, muscle pains, anorexia, nausea, acidosis
who do we assess biotin status
regular whole blood concentration, low (6 ug/day) urinary biotin excretion, increasted 3-hydroxyisovaleric acid/ carnitine (>0.2 umol/mg)
what are s/s of biotin toxicity
trick question! there is none
what is the RDA for biotin for adults
AI for adults is 30ug/day
what is the RDA for biotin for women who are pregnant
AI is 35ug/day
what is the RDA for biotin for women who are lactating
AI is 35ug/day
what is the transporter for biotin
Shared multivitamin transporter (SMVT)
what are the three forms biotin can be found in
protein bound, lyrsine bound, or free
the transporter for biotin requires what other vitamin/mineral
sodium
what is avadin
a protein in raw egg whites that inhibits biotin binding
what is the nonenzymatic function of biotin
transcription factor binding by opening histone through transformation, gene expression.
