Riboflavin / Vitamin B2 Flashcards

1
Q

who and when was riboflavin discovered

A

1917 by Kuhn

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2
Q

who discovered the structure of riboflavin

A

szewnt-gyorgyi and wagner-jaunergy

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3
Q

what are some excellent sources of riboflavin

A

plain greek yogurt, milk, almonds

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4
Q

what are some good sources of riboflavin

A

cottage cheese, portablla mushrooms, eggs

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5
Q

what is riboflavin deficiency called

A

ariboflavinosis

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6
Q

what are the s/s of riboflavin deficiency

A

chiolosis, angular stomatitis, glossitis, magenta tongue, red, bloody, swollen mouth, oculo-orogenital syndrome: neuropathy

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7
Q

who are the populations most at risk for ariboflavinosis

A

DM, trauma, stress, alcoholism, individuals with thyroid/adrenal disease, malabsorption diseases, taking diuretics.

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8
Q

how to measure the status of riboflavin

A

FAD-dependent enzymes: like erythrocyte gluthione reductase. URinary riboflavin excretion (<25ug/g creatinine or <40ug/day indicates deficiency)

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9
Q

what are the toxicity s/s for ariboflavinosis

A

trick question! there are none!

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10
Q

what is the reference range for riboflavin

A

1-19ug/L

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11
Q

what is the RDA for men for riboflavin

A

1.3mg/day

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12
Q

what is the RDA for women for riboflavin

A

1.1mg/day

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13
Q

what is the RDA for pregnant women for riboflavin

A

1.4mg/day

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14
Q

what is the RDA for lactating women for riboflavin

A

1.6mg/day

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15
Q

what is the TUL for riboflavin

A

trick question! there is none!

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16
Q

What is the transporter for riboflavin into the SI

A

energy-dependent riboflavin vitamin transporter 3 (RFVT3) or RFVT1 (basolateral membrane). Diffusion in pharm doses

17
Q

These are the carrier proteins for riboflavin

A

albumin, fibrinogen, globulins, immunoglovulins