Vitamin B12/Cobalamin

Question 1

Vitamin B12 is also known as

Answer 1

Cobalamin

Question 2

When was B12 discovered/isolated

Answer 2

structure in 1926 (Minot and Murphy), isolated 1948 (Smith and Rickes)

Question 3

How was B12 discovered

Answer 3

eating liver (high in b12) would correct pernicious anemia

Question 4

What are some excellent sources of B12

Answer 4

Clams, oysters, salmon, beef sirloin, low fat milk, cod, low fat yogurt, and swiss cheese

Question 5

What are some good sources of B12

Answer 5

Cottage cheese, eggs, pork

Question 6

How much B12 can be stored in the body

Answer 6

2-3mg

Question 7

How is B12 stored (location and molecule)

Answer 7

liver and muscle, adenosylcobalamin

Question 8

What is the name of B12 deficiency

Answer 8

Megaloblastic macrocytic Anemia

Question 9

What are the s/s of B12 deficiency

Answer 9

fatigue, skin pallor, anemia, clumsiness, poor coordination, numbness, pain in extremidies, abnormal gait, irritablity, memory loss, hallucination, psychosis, dementia

Question 10

what are s/s of B12 toxicity

Answer 10

Trick question! there are none.

Question 11

What is the B12 RDA for adults

Answer 11

2.4ug

Question 12

What is the B12 DV for adults

Answer 12

6ug

Question 13

what is the B12 RDA for pregnant women

Answer 13

2.6ug

Question 14

what is the B12 RDA for lactating women

Answer 14

2.8ug

Question 15

What is the recommended B12 intake for older adults

Answer 15

25-100ug

Question 16

What are populations most at risk for B12 deficiency

Answer 16

IBD, Proton Pump Inhibitor Users, Zollinger-Ellison Syndrome, Parasitic Infections, Bacterial Overgrowth