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Step One R&M > Virus stuff > Flashcards

Virus stuff Flashcards

1
Q

Anti-HBs + Anti-HBe + Anti-HBc IgG

A

Recovery

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2
Q

Immunized to HBV serum

A

Anti-HBs

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3
Q

DNA hepatitis virus

A

Hep B

(All others are RNA)

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3
Q

Where does CMV stay latent?

A

Mononuclear cells

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3
Q

Chronic phase serum with low infectivity

A

HBsAG

Anti-HBe

Anti-HBc IgG

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4
Q

Which DNA viruses are not linear?

A

Papilloma

Polyoma

Hepadna

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4
Q

Which DNA virus does not replicate in the nucleus nor has an icosahedral capsid?

A

Pox virus

(remember it’s the largest virus = can carry its own DNA-dep RNA polymerase)

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4
Q

Owl eye inclusions

A

CMV

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4
Q

Waterborne epidemics, hepatitis

A

HEV

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5
Q

Requires another virus

A

HDV requires HBV

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7
Q

HBsAG + Anti-HBe + Anti-HBc IgG

A

Chronic infection with low infectivity

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8
Q
A

Roseola infanatum

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8
Q

Fecal-oral hepatitis viruses

A

HAV

HEV

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8
Q

How do anti-HBV antibodies protect against hepatocellular damage?

A

Antibodies prevent viral entry into cells, so antigens can never be loaded onto MHC class I and presented to CD8+

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9
Q

Hepatits that’s usually asymptomatic

A

HAV

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9
Q

DNA hepadnavirus

A

HBV

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10
Q

Worse prognosis HDV

A

Co-infection with HBV

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12
Q

ssDNA virus

A

Parvovirus

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12
Q
A

Measles

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13
Q

Chronic HBV serum with high infectivity

A

HBsAg

HBeAg

Anti-HBc IgG

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14
Q

Anti-HBe + Anti-HBc IGM

A

Window period (5-6 months after infection)

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15
Q

High fevers for several days that can cause seizures followed by a maculopapular rash

A

Roseola (HHV-6)

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17
Q

Which virus gets its envelope from the nuclear membrane?

A

Herpesviruses

(All other enveloped virus get it from cytoplasmic membrane)

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19
Q

Better or worse prognosis? HDV after HBV

A

Better (Superinfection better than co-infection)

20
Q

Acute phase serum HBV

A

HBsAg

HBeAg

Anti-HBc IgM

21
Q

Hepatitis with short incubation

22
Q

dsRNA virus

A

Reoviridae (Coltivirus, Rotavirus)

23
Q

Replicate in nucleus

A

DNA viruses (except pox virus)

Flu

Retroviruses

23
Q

High mortality in preggos, hepatitis

24
Q

Which DNA virus is not ds?

A

Parvovirus

25
Q

Where do DNA viruses replicate?

A

Nucleus

(Except pox virus, which has its own polymerase)

27
Q

DNA viruses

A

Herpesvirus

Polyomavirus

Papillomavirus

Hepadnavirus

Poxvirus

Parvovirus

Adenovirus

29
Q

Maternal-fetal hepatitis viruses

30
Q

HBsAG + HBeAG + HBcAG IgM

A

Acute phase serum

(1-5 months after infection)

31
Q

Most segmented viruses

A

Reoviruses (rotovirus, coltivirus) ith 10-12 segments

32
Q

RNA flavivirus (hepatitis)

34
Q

No carrier state, hepatitis

35
Q

Where do RNA viruses replicate?

A

Cytoplasm (except flu and retroviruses)

36
Q
A

Roseola (HHV-6)

37
Q

RNA hepavirus

38
Q

Hepatitis virus that increases HCC risk due to chronic inflammation

40
Q

Monospot negative mononucleosis

41
Q

Least segmented virus

A

Arenavirus (LCMV, lassa fever encephalitis)

43
Q
44
Q

Hepatitis virus that increases HCC risk by incorporating into genome and acting as an oncogene

45
Q

Kaposi sarcoma is a neoplasm of ____

A

Endothelial cells

46
Q

Window period serum HBV

A

Anti-HBe

Anti-HBc IgM

47
Q

No HCC risk, hepatitis

48
Q

HBsAg + HBeAg + Anti-HBc IgG

A

Chronic infection with high infectivity

50
Q

Which naked nucleic acid particles would not be infectious?

A

dsRNA (Coltivirus, Rotavirus)

  • ssRNA (Orthomyxoviruses, Paramyxoviruses, Rabies, Ebola, LCMV, Bunyaviridae, Hep D)

**These viruses carry their own polymerases so require in tact virions**

51
Q

Cause of Roseola?

52
Q

A person has anti-HBs in their blood but no anti-HBc. What do you know about this patient?

A

Was vaccinated

53
Q

Unenveloped viruses

A

Adenovirus

Polyoma virus

54
Q

Which RNA viruses don’t replicate in the cytoplasm?

A

Flu, retroviruses

56
Q

RNA picornavirus (hepatitis)

57
Q
A

Congenital rubella

(Blueberry muffin spots = extramedullary hematopoeisis)

58
Q

Segmented viruses

A

All are RNA viruses:

Bunyavirdae

Orthomyxovirus (flu)

Arenavirus (LCMV, Lassa fever)

Reovirus (rotavirus, coltivirus)

59
Q

Recovery phase serum HBV

A

Anti-HBs

Anti-HBc IgG

Step One R&M (38 decks)

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