Virus stuff

Question 1

Anti-HBs + Anti-HBe + Anti-HBc IgG

Answer 1

Recovery

Question 2

Immunized to HBV serum

Answer 2

Anti-HBs

Question 3

DNA hepatitis virus

Answer 3

Hep B

(All others are RNA)

Question 3

Where does CMV stay latent?

Answer 3

Mononuclear cells

Question 3

Chronic phase serum with low infectivity

Answer 3

HBsAG

Anti-HBe

Anti-HBc IgG

Question 4

Which DNA viruses are not linear?

Answer 4

Papilloma

Polyoma

Hepadna

Question 4

Which DNA virus does not replicate in the nucleus nor has an icosahedral capsid?

Answer 4

Pox virus

(remember it’s the largest virus = can carry its own DNA-dep RNA polymerase)

Question 4

Owl eye inclusions

Answer 4

CMV

Question 4

Waterborne epidemics, hepatitis

Answer 4

HEV

Question 5

Requires another virus

Answer 5

HDV requires HBV

Question 7

HBsAG + Anti-HBe + Anti-HBc IgG

Answer 7

Chronic infection with low infectivity

Question 8

Answer 8

Roseola infanatum

Question 8

Fecal-oral hepatitis viruses

Answer 8

HAV

HEV

Question 8

How do anti-HBV antibodies protect against hepatocellular damage?

Answer 8

Antibodies prevent viral entry into cells, so antigens can never be loaded onto MHC class I and presented to CD8+

Question 9

Hepatits that’s usually asymptomatic

Answer 9

HAV

Question 9

DNA hepadnavirus

Answer 9

HBV

Question 10

Worse prognosis HDV

Answer 10

Co-infection with HBV

Question 12

ssDNA virus

Answer 12

Parvovirus

Question 12

Answer 12

Measles

Question 13

Chronic HBV serum with high infectivity

Answer 13

HBsAg

HBeAg

Anti-HBc IgG

Question 14

Anti-HBe + Anti-HBc IGM

Answer 14

Window period (5-6 months after infection)

Question 15

High fevers for several days that can cause seizures followed by a maculopapular rash

Answer 15

Roseola (HHV-6)

Question 17

Which virus gets its envelope from the nuclear membrane?

Answer 17

Herpesviruses

(All other enveloped virus get it from cytoplasmic membrane)

Question 19

Better or worse prognosis? HDV after HBV

Answer 19

Better (Superinfection better than co-infection)

Question 20

Acute phase serum HBV

Answer 20

HBsAg HBeAg Anti-HBc IgM

Question 21

Hepatitis with short incubation

Answer 21

HAV HEV

Question 22

dsRNA virus

Answer 22

Reoviridae (Coltivirus, Rotavirus)

Question 23

Replicate in nucleus

Answer 23

DNA viruses (except pox virus) Flu Retroviruses

Question 23

High mortality in preggos, hepatitis

Answer 23

HEV

Question 24

Which DNA virus is not ds?

Answer 24

Parvovirus

Question 25

Where do DNA viruses replicate?

Answer 25

Nucleus (Except pox virus, which has its own polymerase)

Question 27

DNA viruses

Answer 27

Herpesvirus Polyomavirus Papillomavirus Hepadnavirus Poxvirus Parvovirus Adenovirus

Question 29

Maternal-fetal hepatitis viruses

Answer 29

HBV HDV

Question 30

HBsAG + HBeAG + HBcAG IgM

Answer 30

Acute phase serum | (1-5 months after infection)

Question 31

Most segmented viruses

Answer 31

Reoviruses (rotovirus, coltivirus) ith 10-12 segments

Question 32

RNA flavivirus (hepatitis)

Answer 32

HCV

Question 34

No carrier state, hepatitis

Answer 34

HAV HEV

Question 35

Where do RNA viruses replicate?

Answer 35

Cytoplasm (except flu and retroviruses)

Question 36

Answer 36

Roseola (HHV-6)

Question 37

RNA hepavirus

Answer 37

HEV

Question 38

Hepatitis virus that increases HCC risk due to chronic inflammation

Answer 38

HCV

Question 40

Monospot negative mononucleosis

Answer 40

CMV

Question 41

Least segmented virus

Answer 41

Arenavirus (LCMV, lassa fever encephalitis)

Question 43

Answer 43

Rubella

Question 44

Hepatitis virus that increases HCC risk by incorporating into genome and acting as an oncogene

Answer 44

HBV

Question 45

Kaposi sarcoma is a neoplasm of \_\_\_\_

Answer 45

Endothelial cells

Question 46

Window period serum HBV

Answer 46

Anti-HBe Anti-HBc IgM

Question 47

No HCC risk, hepatitis

Answer 47

HAV HEV

Question 48

HBsAg + HBeAg + Anti-HBc IgG

Answer 48

Chronic infection with high infectivity

Question 50

Which naked nucleic acid particles would not be infectious?

Answer 50

dsRNA (Coltivirus, Rotavirus) - ssRNA (Orthomyxoviruses, Paramyxoviruses, Rabies, Ebola, LCMV, Bunyaviridae, Hep D) \*\*These viruses carry their own polymerases so require in tact virions\*\*

Question 51

Cause of Roseola?

Answer 51

HHV-6

Question 52

A person has anti-HBs in their blood but no anti-HBc. What do you know about this patient?

Answer 52

Was vaccinated

Question 53

Unenveloped viruses

Answer 53

Adenovirus Polyoma virus

Question 54

Which RNA viruses don't replicate in the cytoplasm?

Answer 54

Flu, retroviruses

Question 56

RNA picornavirus (hepatitis)

Answer 56

HAV

Question 57

Answer 57

Congenital rubella (Blueberry muffin spots = extramedullary hematopoeisis)

Question 58

Segmented viruses

Answer 58

All are RNA viruses: Bunyavirdae Orthomyxovirus (flu) Arenavirus (LCMV, Lassa fever) Reovirus (rotavirus, coltivirus)

Question 59

Recovery phase serum HBV

Answer 59

Anti-HBs Anti-HBc IgG