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Step One R&M > Drug thangs > Flashcards

Drug thangs Flashcards

1
Q

Omalizumab

A

IgE

Prevents IgE from binding to its receptor

Allergic asthma

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2
Q

Cetuximab

A

EGFR

Stage IV CRC, head and neck cancer

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2
Q

RANKL mab

A

Denosumab

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4
Q

Prevents IgE binding to its receptor

A

Omalizimuab

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4
Q

MAB that inhibits neutrophil adhesion

A

Natalizumab (alpha4-integrin)

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6
Q

Avoid in pregnancy due to gray baby syndrome

A

Chloramphenicol

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7
Q

Avoid in pregnancy due to kernicterus

A

Sulfas (severe jaundice)

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8
Q

Avoid in pregnancy due to dicolored teeth/bones

A

Tetracyclines

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9
Q

Natalizumab

A

Alpha4-integrin

MS, Chron’s

Increased risk of PML

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10
Q

Infliximab

A

TNFalpha

IBD/RA/ankylosing spondylitis/psoriasis

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10
Q

RSF F protein mab

A

Palivizumab

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11
Q

HER2/neu mab

A

Trastuzumab

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12
Q

MAB that can causes PML

A

Natalizumab

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13
Q

Antidote that is a mab

A

Digoxin immune Fab

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14
Q

Avoid in pregnancy due to teratogenic effects

A

Griseofulvin

Ribavirin

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14
Q

CD20 mab

A

Rituximab

15
Q

Avoid in pregnancy due to ototoxicity

A

Aminoglycosides

15
Q

Palivizumab

A

RSV F protein

Prevents RSV in high-risk infants

16
Q

EGFR mab

A

Cetuximab

17
Q

MAB for CLL

A

Alemtuzumab (CD52)

19
Q

CD52 mab

A

Alemtuzumab

21
Q

Bevacizumab

A

VEGF

CRC, renal cell carcinoma

22
Q

MAB for osteoporosis

A

Denosumab (RANKL)

23
Q

GpIIb/IIIa mab

A

Abciximab

24
Q

Trastuzumab

A

HER2/neu

Breast CA, gastric CA

24
Q

Adalimumab

A

CD20

RA/IBD/ankylosing spondylitis/psoriasis

25
Q

Avoid in pregnancy due to embryotoxic effects

A

Clarithromycin

27
Q

Abciximab

A

GpIIb/IIIa

Prevents fibrinogen binding = no platelet aggregation

Prevention of ischemia in patients undergoing coronary interventions

28
Q

Patient with MS or Chron’s develops rapidly progressive neuro signs

A

Think natalizumab = increased risk of PML

29
Q

Alemtuzumab

A

CD52

CLL

(aLYMtuzumab)

30
Q

TNFalpha mab

A

Infliximab

Adalimumab

31
Q

Avoid in pregnancy due to cartilage damage

A

Fluoroquinolones

32
Q

8 antibiotics to avoid in pregnancy

A

Sulfas

Aminoglycosides

Chloramphenicol

Griseofulvin

Ribavirin

Tetracyclines

Clarithromycin

Fluoroquinolones

34
Q

VEGF mab

A

Bevacizumab

35
Q

IgE mab

A

Omalizumab

36
Q

Denosumab

A

RANKL

Inhibits osteoclast activation

Osteoporosis

37
Q

Alpha4-integrin mab

A

Natalizumab

38
Q

Rituximab

A

CD20

RA (+ MTX), B cell lymphoma, ITP

Step One R&M (38 decks)

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