Drug thangs

Question 1

Omalizumab

Answer 1

IgE

Prevents IgE from binding to its receptor

Allergic asthma

Question 2

Cetuximab

Answer 2

EGFR

Stage IV CRC, head and neck cancer

Question 2

RANKL mab

Answer 2

Denosumab

Question 4

Prevents IgE binding to its receptor

Answer 4

Omalizimuab

Question 4

MAB that inhibits neutrophil adhesion

Answer 4

Natalizumab (alpha4-integrin)

Question 6

Avoid in pregnancy due to gray baby syndrome

Answer 6

Chloramphenicol

Question 7

Avoid in pregnancy due to kernicterus

Answer 7

Sulfas (severe jaundice)

Question 8

Avoid in pregnancy due to dicolored teeth/bones

Answer 8

Tetracyclines

Question 9

Natalizumab

Answer 9

Alpha4-integrin

MS, Chron’s

Increased risk of PML

Question 10

Infliximab

Answer 10

TNFalpha

IBD/RA/ankylosing spondylitis/psoriasis

Question 10

RSF F protein mab

Answer 10

Palivizumab

Question 11

HER2/neu mab

Answer 11

Trastuzumab

Question 12

MAB that can causes PML

Answer 12

Natalizumab

Question 13

Antidote that is a mab

Answer 13

Digoxin immune Fab

Question 14

Avoid in pregnancy due to teratogenic effects

Answer 14

Griseofulvin

Ribavirin

Question 14

CD20 mab

Answer 14

Rituximab

Question 15

Avoid in pregnancy due to ototoxicity

Answer 15

Aminoglycosides

Question 15

Palivizumab

Answer 15

RSV F protein

Prevents RSV in high-risk infants

Question 16

EGFR mab

Answer 16

Cetuximab

Question 17

MAB for CLL

Answer 17

Alemtuzumab (CD52)

Question 19

CD52 mab

Answer 19

Alemtuzumab

Question 21

Bevacizumab

Answer 21

VEGF

CRC, renal cell carcinoma

Question 22

MAB for osteoporosis

Answer 22

Denosumab (RANKL)

Question 23

GpIIb/IIIa mab

Answer 23

Abciximab

Question 24

Trastuzumab

Answer 24

HER2/neu Breast CA, gastric CA

Question 24

Adalimumab

Answer 24

CD20 RA/IBD/ankylosing spondylitis/psoriasis

Question 25

Avoid in pregnancy due to embryotoxic effects

Answer 25

Clarithromycin

Question 27

Abciximab

Answer 27

GpIIb/IIIa Prevents fibrinogen binding = no platelet aggregation Prevention of ischemia in patients undergoing coronary interventions

Question 28

Patient with MS or Chron's develops rapidly progressive neuro signs

Answer 28

Think natalizumab = increased risk of PML

Question 29

Alemtuzumab

Answer 29

CD52 CLL (aLYMtuzumab)

Question 30

TNFalpha mab

Answer 30

Infliximab Adalimumab

Question 31

Avoid in pregnancy due to cartilage damage

Answer 31

Fluoroquinolones

Question 32

8 antibiotics to avoid in pregnancy

Answer 32

Sulfas Aminoglycosides Chloramphenicol Griseofulvin Ribavirin Tetracyclines Clarithromycin Fluoroquinolones

Question 34

VEGF mab

Answer 34

Bevacizumab

Question 35

IgE mab

Answer 35

Omalizumab

Question 36

Denosumab

Answer 36

RANKL Inhibits osteoclast activation Osteoporosis

Question 37

Alpha4-integrin mab

Answer 37

Natalizumab

Question 38

Rituximab

Answer 38

CD20 RA (+ MTX), B cell lymphoma, ITP