Cardio, renal, pulm equations Flashcards
πBS
Usually equals zero
(shouldn’t have any protein in BS)
HH equation
pH = 6.1 + log(HCO3-/0.03xPCO2)
CO x O2 content =
O2 delivery to tissues
GFR x Px =
Filtered load
(Pc - PBS) - (πc - πBS) =
Net filtration pressure (Pnet)
Clearance =
UxV/Px
RPF/(1-HCT)=
RBF
PVR =
Ppulm artery- PLA
CO
(b/c R = change in P/Q)
RPF =
UPAH- V/PPAH
Excretion rate =
Ux x V
Respiratory quotient =
CO2 produced/O2 consumed
Hb x 1.34
Oxygen binding capacity
2/3(DBP) + 1/3(SBP)
MAP
CO/SV
HR
PAo2 =
~ 150 - PaCO2/0.8
PI02 - (PaCO2/R)
Here, R is the respiratory quotient
Net filtration pressure (Pnet) =
(Pc - PBS) - (πc - πBS)
Accuracy of CRT as measurement of GFR?
Overestimates because CRT is slightly secreted
LaPlace’s Law
Wall tension = Pressure x radius/2 x wall thickness
Accuracy of PAH as measurement of RPF?
Underestimates by ~10% b/c not 100% is excreted
(VT - VD) x RR =
VA
Oxygen content =
(O2 binding capacity x O2 sat) + dissolved O2
Rate of O2 consumption
Arterial O2 - Venous O2
Cardiac output
(Fick principle)
Use inulin or CRT clearance to estimate:
GFR
Changes in CO in early vs. late exercise
Early = increase in HR and SV maintatin CO
Late = only increase in HR maintains CO b/c SV plateaus
GFR =
Uinulin x V/Pinulin
Kf[(Pc-PBS) - (πc-πBS)