Leptospira, Babesia, zoonooses Flashcards
Rats and prarie dogs are reservoirs
Plague (Yersinis pestis)
Only rickettsial organism that doesn’t cause rash
Coxiella burnetti
Chubby safety pins
Yersinia pestis (plague)
Q fever
Coxiella burnetti
Spreads rapidly in skin and subQ tissue
Pasturella (cellulitis, osteomyelitis)
Swollen, inflammed lymph node
Bubo (Yersinia pestis)

How is the agent of relapsing fever transmitted?
Via body lice
(Borrelia recurrentis)
Morulae
Erlichiosis, Anaplasmosis
(Berry-like intracytoplasmic inclusions)

Asplenia increases risk of infection
Babesiosis
Forms spores
Coxiella burnetti
Fever, azotemia, hemorrhage, anemia, jaundice
Weil disease
(icterohemorrhagic leptospirosis)
Localize in reticuloendothelial cells
Brucella (undulant fever)
Francisella (tularemia)
Plague
Yersinia pestis
What are the symptoms of leptospirosis?
Flu-like sx, conjuncivitis without exudate, jaundice, photophobia
Epidemic vs endemic typhus
Epidemic = Rickettsia prowasekii, lice
Endemic = Rickettsia typhus, fleas
What are some vectors of Campylobacter jejuni besides humans?
Puppies, livestock (undercooked meat)
Rash that starts at wrist and ankles and spreads to palms and soles
RMSF (Rickettsia rickettsii)
Granulocytes with morula
Anaplasma
Symptoms of babesiosis?
Fever, hemolytic anemia
Rash that starta on trunk and spreads to limbs but spares palms and soles
Typhus
Mandatory 72 hour quarantine
Yersinia pestis (plague)
Only rickettsial organism with no arthropod vector
Coxiella burnetti
(Aerosols!!)
How are Leptospira transmitted?
Water contaminated with animal urine
Maltese cross
Babesiosis
Cellulitis, osteomyelitis
Pasturella (G- coccobacillus)
Spread via cat and dog bites
Photosensitivity, jaundice, flu-like sx, conjunctival suffusion
Leptospirosis
Monocytes with morula
Ehrlichiosis
How is the agent of Q fever transmitted?
Aerosols of livestock placenta
In what demographic is leptosprosis prevalent?
Surfers, Hawaiins
(transmitted in water)

Babesiosis
(notice the maltese crosses)
Rickettsia prowazekii
Epidemic typhus (lice)
Undulent fever
Brucellosis
Under what classification of bugs do Leptospira fall?
Spriochetes
Ticks, rabbits, deer fly
Tularemia
Where is babesiosis prevalent?
Northeastern US
Parrots
C. psittaci
Cat and dog bites
Pasturella (cellulitis, osteomyelitis)
Bartonella henslae (Cat scratch fever)
Killed vaccine for high-risk population
Yersinia pestis (plague)
How is the agent of unduldent fever transmitted?
Unpasteurized dairy
(Brucella)
Fleas
Rickettsia typhus (endemic typhus)
Yersinia pestis (plague)
Dermacentor ticks
Rickettsia rickettsii (RMSF)
Lice
Relapsing fever (Borrelia recurrentis)
Epidemic typhus (Rickettsia recurrentis)
Ioxedes tick
Anaplasma
Bartonella
Babesia
Lone star ticks
Erlichiosis
Armadillo
Leprosy
Relapsing fever
Borrelia recurrentis
Very low ID50/one of the most virulent organisms
Yersinia pestis (plague)
Treatment for all rickettsial diseases
Doxy
What is Weil disease?
Icterohemorrhagic leptospirosis - fever, hemorrhage, azotemia and jaundice from renal and hepatic damage, anemia
Rickettsia rickettsii
RMSF
Animal urine
Leptospirosis
Rickettsia typhi
Endemic typhus
Factors needed for rickettsial growth
CoA and NAD+ becauses they can’t synthesize ATP