Rate-limiting enzymes of metabolic pathways Flashcards
1
Q
+ ADP
- ATP, NADPH
A
TCA cycle
2
Q
+ AMP, F-2,6-BP
- ATP, citrate
A
Glycolysis
2
Q
- Malonyl-Coa
A
FA oxidation
3
Q
+ ATP, acetyl-CoA
- F-2,6-BP, AMP
A
Gluconeogenesis
4
Q
+ Insulin, citrate
- glucagon, palmitoyl-CoA
A
FA synthesis
5
Q
Gluconeogenesis
A
Fructose-1,6-bisphosphatase
6
Q
+ epinephrine, glucagon, AMP
- insulin, G6P, ATP
A
Glycogenolysis
6
Q
+ Insulin, thyroxine
- Glucagon, cholesterol
A
Cholesterol synthesis
8
Q
TCA cycle
A
Isocitrate dehydrogenase
8
Q
HMP shunt
A
G6PD
9
Q
+ N-acetylglutamate
A
Urea cycle
10
Q
+ G6P, insulin, cortisol
- glucagon, epinephrine
A
Glycogenesis
11
Q
+ NADP-
- NADPH
A
HMP shunt
12
Q
Glycogenolysis
A
Glycogen phosphorylase
13
Q
De novo pyrimidine synthesis
A
Carbamoyl phosphatae synthetase II
