Rate-limiting enzymes of metabolic pathways Flashcards by Amanda Box

Q

+ ADP

ATP, NADPH

A

TCA cycle

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Q

+ AMP, F-2,6-BP

ATP, citrate

A

Glycolysis

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Q

Malonyl-Coa

A

FA oxidation

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Q

+ ATP, acetyl-CoA

F-2,6-BP, AMP

A

Gluconeogenesis

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Q

+ Insulin, citrate

glucagon, palmitoyl-CoA

A

FA synthesis

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Q

Gluconeogenesis

A

Fructose-1,6-bisphosphatase

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Q

+ epinephrine, glucagon, AMP

insulin, G6P, ATP

A

Glycogenolysis

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Q

+ Insulin, thyroxine

Glucagon, cholesterol

A

Cholesterol synthesis

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Q

TCA cycle

A

Isocitrate dehydrogenase

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Q

HMP shunt

A

G6PD

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Q

+ N-acetylglutamate

A

Urea cycle

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Q

+ G6P, insulin, cortisol

glucagon, epinephrine

A

Glycogenesis

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Q

+ NADP-

NADPH

A

HMP shunt

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Q

Glycogenolysis

A

Glycogen phosphorylase

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Q

De novo pyrimidine synthesis

A

Carbamoyl phosphatae synthetase II

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Q

AMP, IMP, GMP

A

De novo purine synthesis

Q

Ketogenesis

A

HMG CoA synthase

Q

De novo purine synthesis

A

Glutamine-PRPP-amidotransferase

Q

Glycogenesis

A

Glycogen synthase

Q

Urea cycle

A

Carbamoyl phosphate synthetase I

Q

Cholesterol synthesis

A

HMG CoA reductase

Q

Fatty acid oxidation

A

Carnitine acyltransferase I

Q

Glycolysis

A

PFK-1

Q

Fatty acid synthesis

A

Acetyl-CoA carboxylase