Viral hepatitis Flashcards

1
Q

Hep A - transmission

A

Faecal-oral

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2
Q

Hep A - cause

A
Travellers (India)
Poor hygiene
Overcrowding
Gay men 
PWID
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3
Q

Hep A - acute or chronic?

A

Acute

NEVER chronic

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4
Q

Hep A - incidence in UK

A

Decreasing

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5
Q

Hep A - investigations

A

Lab conformation

  • clotted blood for serology
  • Hep A IgM (marker of acute current infection)
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6
Q

Hep B - transmission, cause

A

Sex
Mother to child - vertical
Blood - tattoos, blood transfusion, needlestick

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7
Q

Hep B - acute or chronic?

A

Acute and chronic
Adult infected - more likely to be acute
Child infected - more likely to be chronic

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8
Q

Hep B - investigations

A

HBsAg - antigen present on surface of hep B virus, indicates current infection (either acute or chronic)

HBeAg - present in highly infectious individuals

Anti-HBs - hep B surface antibody. Present if a person has been vaccinated against the disease or has gained natural immunity

Anti HBc - Previous or ongoing infection. Pt has had the infection at some point

IgM anti HBc - Acute infection, infection in the past 6 months

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9
Q

Hep B - management (chronic)

A

Peg interferon alone

Antiviral drugs (-ivir)

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10
Q

Hep C - transmission, cause

A
Similar to hep B 
Sex
Mother to child
Blood - tattoos, needlestick, blood transfusion
IVDU
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11
Q

Hep C - acute or chronic?

A

Acute and chronic

Most people go on to be chronically infected

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12
Q

Hep C - investigations

A

Test for antibody to Hep C
- negative: not infected
- positive: infected. Must check if it is active or past infection
—- test for hep C virus RNA by PCR
Antibody + RNA present = active infection

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13
Q

Hep C - management

A

Antiviral regime

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14
Q

Hep D - transmission, cause

A

Only present if Hep B is already present

- must be infected with Hep B first

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15
Q

Hep E - transmission, cause

A

Tropics
Zoonoses
Faecal-oral transmission

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16
Q

Hep E - acute or chronic

A

Acute

17
Q

Hep E - incidence

A

More common than Hep A

18
Q

Which viral hepatitis is the most common in the UK?

A

Hep C

19
Q

Which hepatitis can you only get if you are already infected with another hepatitis?

A

Hep D (also have Hep B)