Barrett's Oesophagus Flashcards

1
Q

Definition

A

Replacement of stratified squamous epithelium of the oesophagus by columnar, glandular epithelium of the stomach
Metaplastic change

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2
Q

Is Barrett’s oesophagus reversible?

A

NO

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3
Q

Cause

A

Due to persistent reflux of acid/bile (GORD)

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4
Q

Histology

A

Red, velvety mucosa in lower 1/3 oesophagus

Columnar lined mucosa in oesophagus

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5
Q

Risks

A

Risk of developing dysplasia -> adenocarcinoma of oesophagus

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6
Q

Clinical presentation

A
Signs and symptoms of worsening GORD:
heartburn
Hypersalivation
Acid reflux
Dysphagia
Odynophagia
Weight loss
Hoarseness
Cough 
Chest pain
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7
Q

Investigations

A

Endoscopy

Biopsy

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