Barrett's Oesophagus Flashcards
1
Q
Definition
A
Replacement of stratified squamous epithelium of the oesophagus by columnar, glandular epithelium of the stomach
Metaplastic change
2
Q
Is Barrett’s oesophagus reversible?
A
NO
3
Q
Cause
A
Due to persistent reflux of acid/bile (GORD)
4
Q
Histology
A
Red, velvety mucosa in lower 1/3 oesophagus
Columnar lined mucosa in oesophagus
5
Q
Risks
A
Risk of developing dysplasia -> adenocarcinoma of oesophagus
6
Q
Clinical presentation
A
Signs and symptoms of worsening GORD: heartburn Hypersalivation Acid reflux Dysphagia Odynophagia Weight loss Hoarseness Cough Chest pain
7
Q
Investigations
A
Endoscopy
Biopsy