Chronic liver disease Flashcards
1
Q
Duration
A
Greater than 6 months
2
Q
What is it?
A
Progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis
3
Q
Causes
A
Alcohol NAFLD Vital hepatitis Autoimmune liver disease - PBC, PSC, autoimmune hepatitis Haemochromatosis Wilsons disease alpha 1 antitrypsin budd chiari
4
Q
Disease progression
A
Causes Recurrent inflammation Fibrosis Compensated cirrhosis Decompensated cirrhosis Liver failure
5
Q
Investigations
A
Albumin - decreased
Prothrombin time - increased