Malabsorption Flashcards

1
Q

Definition

A

Defective mucosal absorption due to

  • defective luminal digestion
  • mucosal disease
  • structural disorders
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2
Q

Causes

A
Crohn's disease
Coeliac disease 
Post infections - giardia 
Biliary obstruction 
Cirrhosis 
Whipple's disease 
Tropical sprue
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3
Q

Whipple’s disease - cause

A

T Whipplei micro-organism

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4
Q

Whipple’s disease - genetics

A

HLA-B27

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5
Q

Whipple’s disease - clinical presentation

A
Multi system involvement 
Weight loss
Diarrhoea
Steatorrhoea 
Abdominal distension 
Fever
Arthritis
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6
Q

Whipple’s disease - investigations

A

Microscopy

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7
Q

Whipple’s disease - management

A

Antimicrobial

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8
Q

Tropical sprue - cause

A

Infection colonises intestines

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9
Q

Tropical sprue - clinical presentation

A
Diarrhoea
Steatorrhoea
Weight loss
Nausea
Anorexia 
Anaemia
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10
Q

Tropical sprue - investigations

A

Biopsy

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11
Q

Tropical sprue - management

A

Tetracycline

Folic acid

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12
Q

Giardia lambia - causes

A

Traveling to areas with contaminated water supply

Swimming in pools

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13
Q

Giradia lambia - clinical presentation

A
Watery diarrhoea
Steatorrhoea 
Weight loss 
Abdominal pain 
Nausea
Vomiting
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14
Q

Giardia lambia - investigations

A

Stool culture x3

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15
Q

Giardia lambia - management

A

Metronidazole

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16
Q

Schilling’s test - what is it used for?

A

To detect bacterial overgrowth

17
Q

Malabsorption PMH

A

Gastric or small bowel resection

18
Q

Investigations

A
FBC 
LFT 
Stool culture
Endoscopy 
Imaging - AXR, CT scan, MRI