GORD Flashcards

1
Q

Acute/Chronic oesophagitis?

A

Chronic

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2
Q

What is GORD?

A

Inflammation of the oesophagus due to refluxed low pH gastric content

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3
Q

Causes of GORD

A
Defective LOS 
Abnormal oesophageal motility
Increased intra abdominal pressure (obesity, pregnancy)
Alcohol
Tobacco
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4
Q

Clinical Presentation

A

Heatburn - burning sensation retrosternally
Acid reflux
Waterbrash - hypersalivation

Dysphagia
Odynophagia
Weight loss 
Hoarseness
Chest pain
Cough
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5
Q

Histology

A

Basal zone epithelial expansion
Increased cell proliferation
Eosinophils and neutrophils recruited to squamous mucosa

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6
Q

Investigations

A

Endoscopy - gold standard
Barium Swallow
Oesophageal manometry - evaluates LOS function

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7
Q

Management

A

PPI - reduce amount of acid produced by stomach
H2RA - eg ranitidine
Antacids - for symptomatic relief
Surgery

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8
Q

Complications

A

Ulceration
Stricture
Barret’s oesophagus
Malignancy

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