Urinary System Flashcards

1
Q

the urinary system regulates ______, _______, and _______

A

plasma ion concentrations (NA+,K+,Cl-,Ca2+), blood volume and pressure (ex. renin), plasma pH

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2
Q

the urinary system conserves ____ by preventing _____

A

nutrients, excretion

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3
Q

the urinary system eliminates _______

A

organic wastes (urea, uric acid, drugs)

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4
Q

the urinary system synthesizes_____

A

hormones: calcitrol (derivative of D3 vitamin), erythyopoietin, renin)

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5
Q

path of urine drainage

A

collecting duct-papillary duct-minor calyx-major calyx-renal pelvis-ureter-urinary bladder

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6
Q

the ureters and urinary bladder are lined with…

A

transitional epithelium

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7
Q

blood supply of the kidneys

A

renal artery-afferent arterioles-glomerular capillaries-efferent arterioles-peritubular capillaries-renal vein

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8
Q

what are macula densa?

A

cells in the wall of the thick ascending loop of Henle, monitors electrolyte concentration in tubular fluid, secretes paracrine that constricts the afferent arteriole to regulate GFR

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9
Q

what are the juxtaglomerular cells?

A

cells in the wall of the afferent arteriole-modified smooth muscle cells, secrete renin

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10
Q

juxtaglomerular apparatus

A

helps regulate blood pressure within the kidney, formed by juxtaglomerular cells and macula densa

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11
Q

nephrons that are juxtamedullary have _____ and ____. this makes them better at ______ ______.

A

longer loops of Henle, collecting ducts, concentrating filtrate

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12
Q

proximal convoluted tubule (PCT) epithelium

A

simple cuboidal with prominent brush border or microvilli

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13
Q

nephron loop: descending limb and thin ascending limb

A

simple squamous epithelium

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14
Q

most of distal convoluted tubule (DCT)

A

simple cuboidal epithelial

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15
Q

last part of DCT and all of collecting duct

A

simple cuboidal epithelium consisting of principal cells and intercalated cells

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16
Q

nephrons perform:

A

filtration, reabsorption, and secretion

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17
Q

glomerular filtration

A

blood plasma and dissolved substances get filtered into the glomerular capsule

18
Q

tublular reabsorption

A

all alon renal tubule and collecting duct things are reabsorbed from the renal tubule lumen into the peritubular capillaries and ultimately into the blood

19
Q

tubular secretion

A

all along the renal tubule and collecting duct, substances get secreted from the peritubular capillaries into the renal tubule, ultimately make their way into the urine.

20
Q

renal corpuscle=

A

bowman’s capsule+glomerulus

site of filtration

21
Q

mesangial cells

A

between glomerular capillaries and afferent and efferent arteriole, can contract and regulate glomerular filtration rate

22
Q

podocytes

A

foot processes (PEDICELS) that create filtration slits that only allow passage of smaller molecules

23
Q

what is the importance of the fenestration of glomerular endothelial cells?

A

prevents filtration of blood cells but allows all components of blood plasma to pass through

24
Q

basal lamina of glomerulus prevents…

A

filtration of larger proteins

25
Q

renin

A

involved in forming the hormone Angiotensin II that causes an increase in blood pressure

26
Q

extraglomerular mesangial cells

A

contractile cells that help regulate glomerular filtration

27
Q

renal processes

A

filtration, reabsorption, secretionm excretion

28
Q

renal filtration

A

occurs at glomerulus movement of fluid and substance out of the glomerular capillary into Bowman’s capsule

29
Q

renal reabsorption

A

movement of fluid and substances from the nephron tubule into the peritubular capillaries or vasa recta

30
Q

renal secretion

A

movement of fluid and substances from the peritubular capillaries into the nephron tubule

31
Q

renal excretion

A

into urine

32
Q

when substances are reabsorbed, then enter the _______

A

peritubular capillaries

33
Q

aldosterone

A

secreted by adrenal cortex and increases the reabsorption of Na+ and secretion of K+ by the distal tubule and collecting duct

34
Q

anti-diuretic hormone/vasopressin

A

secreted by the posterior pituitary gland and increases the reabsorption water by the distal tubule and collecting duct

35
Q

principle cells in the DT and CD are the cells that have _____ with ____ and _____

A

receptors, aldosterone, ADH

36
Q

external urethral sphincter

A

voluntary control of opening and closing of urethra, skeletal muscle

37
Q

internal urethral sphincter

A

involuntary opening and closing of urethra, smooth muscle

38
Q

detrusor muscle

A

smooth muscle that contracts to push urine into urethra

39
Q

micturition reflex

A

discharge of urine from the urinary bladder

40
Q

micturition reflex: sensory

A

when bladder volume reaches certain level, sensory nerves send messages to the micturition center in the spinal cord

41
Q

micturition reflex: motor

A

the parasympathetic NS causes contraction of the detrusor muscle and inhibition of the internal urethral sphincter and the somatic NS inhibits the external urethral sphincter

42
Q

male urethras vs female urethras

A

5x longer in males
divided into 3 segments in males but one short tube for females
common duct for urinary and reproductive system in males, completely separate in females