Urinary System Flashcards
the urinary system regulates ______, _______, and _______
plasma ion concentrations (NA+,K+,Cl-,Ca2+), blood volume and pressure (ex. renin), plasma pH
the urinary system conserves ____ by preventing _____
nutrients, excretion
the urinary system eliminates _______
organic wastes (urea, uric acid, drugs)
the urinary system synthesizes_____
hormones: calcitrol (derivative of D3 vitamin), erythyopoietin, renin)
path of urine drainage
collecting duct-papillary duct-minor calyx-major calyx-renal pelvis-ureter-urinary bladder
the ureters and urinary bladder are lined with…
transitional epithelium
blood supply of the kidneys
renal artery-afferent arterioles-glomerular capillaries-efferent arterioles-peritubular capillaries-renal vein
what are macula densa?
cells in the wall of the thick ascending loop of Henle, monitors electrolyte concentration in tubular fluid, secretes paracrine that constricts the afferent arteriole to regulate GFR
what are the juxtaglomerular cells?
cells in the wall of the afferent arteriole-modified smooth muscle cells, secrete renin
juxtaglomerular apparatus
helps regulate blood pressure within the kidney, formed by juxtaglomerular cells and macula densa
nephrons that are juxtamedullary have _____ and ____. this makes them better at ______ ______.
longer loops of Henle, collecting ducts, concentrating filtrate
proximal convoluted tubule (PCT) epithelium
simple cuboidal with prominent brush border or microvilli
nephron loop: descending limb and thin ascending limb
simple squamous epithelium
most of distal convoluted tubule (DCT)
simple cuboidal epithelial
last part of DCT and all of collecting duct
simple cuboidal epithelium consisting of principal cells and intercalated cells
nephrons perform:
filtration, reabsorption, and secretion
glomerular filtration
blood plasma and dissolved substances get filtered into the glomerular capsule
tublular reabsorption
all alon renal tubule and collecting duct things are reabsorbed from the renal tubule lumen into the peritubular capillaries and ultimately into the blood
tubular secretion
all along the renal tubule and collecting duct, substances get secreted from the peritubular capillaries into the renal tubule, ultimately make their way into the urine.
renal corpuscle=
bowman’s capsule+glomerulus
site of filtration
mesangial cells
between glomerular capillaries and afferent and efferent arteriole, can contract and regulate glomerular filtration rate
podocytes
foot processes (PEDICELS) that create filtration slits that only allow passage of smaller molecules
what is the importance of the fenestration of glomerular endothelial cells?
prevents filtration of blood cells but allows all components of blood plasma to pass through
basal lamina of glomerulus prevents…
filtration of larger proteins