Urinary System Flashcards

1
Q

the urinary system regulates ______, _______, and _______

A

plasma ion concentrations (NA+,K+,Cl-,Ca2+), blood volume and pressure (ex. renin), plasma pH

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2
Q

the urinary system conserves ____ by preventing _____

A

nutrients, excretion

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3
Q

the urinary system eliminates _______

A

organic wastes (urea, uric acid, drugs)

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4
Q

the urinary system synthesizes_____

A

hormones: calcitrol (derivative of D3 vitamin), erythyopoietin, renin)

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5
Q

path of urine drainage

A

collecting duct-papillary duct-minor calyx-major calyx-renal pelvis-ureter-urinary bladder

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6
Q

the ureters and urinary bladder are lined with…

A

transitional epithelium

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7
Q

blood supply of the kidneys

A

renal artery-afferent arterioles-glomerular capillaries-efferent arterioles-peritubular capillaries-renal vein

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8
Q

what are macula densa?

A

cells in the wall of the thick ascending loop of Henle, monitors electrolyte concentration in tubular fluid, secretes paracrine that constricts the afferent arteriole to regulate GFR

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9
Q

what are the juxtaglomerular cells?

A

cells in the wall of the afferent arteriole-modified smooth muscle cells, secrete renin

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10
Q

juxtaglomerular apparatus

A

helps regulate blood pressure within the kidney, formed by juxtaglomerular cells and macula densa

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11
Q

nephrons that are juxtamedullary have _____ and ____. this makes them better at ______ ______.

A

longer loops of Henle, collecting ducts, concentrating filtrate

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12
Q

proximal convoluted tubule (PCT) epithelium

A

simple cuboidal with prominent brush border or microvilli

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13
Q

nephron loop: descending limb and thin ascending limb

A

simple squamous epithelium

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14
Q

most of distal convoluted tubule (DCT)

A

simple cuboidal epithelial

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15
Q

last part of DCT and all of collecting duct

A

simple cuboidal epithelium consisting of principal cells and intercalated cells

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16
Q

nephrons perform:

A

filtration, reabsorption, and secretion

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17
Q

glomerular filtration

A

blood plasma and dissolved substances get filtered into the glomerular capsule

18
Q

tublular reabsorption

A

all alon renal tubule and collecting duct things are reabsorbed from the renal tubule lumen into the peritubular capillaries and ultimately into the blood

19
Q

tubular secretion

A

all along the renal tubule and collecting duct, substances get secreted from the peritubular capillaries into the renal tubule, ultimately make their way into the urine.

20
Q

renal corpuscle=

A

bowman’s capsule+glomerulus

site of filtration

21
Q

mesangial cells

A

between glomerular capillaries and afferent and efferent arteriole, can contract and regulate glomerular filtration rate

22
Q

podocytes

A

foot processes (PEDICELS) that create filtration slits that only allow passage of smaller molecules

23
Q

what is the importance of the fenestration of glomerular endothelial cells?

A

prevents filtration of blood cells but allows all components of blood plasma to pass through

24
Q

basal lamina of glomerulus prevents…

A

filtration of larger proteins

25
renin
involved in forming the hormone Angiotensin II that causes an increase in blood pressure
26
extraglomerular mesangial cells
contractile cells that help regulate glomerular filtration
27
renal processes
filtration, reabsorption, secretionm excretion
28
renal filtration
occurs at glomerulus movement of fluid and substance out of the glomerular capillary into Bowman's capsule
29
renal reabsorption
movement of fluid and substances from the nephron tubule into the peritubular capillaries or vasa recta
30
renal secretion
movement of fluid and substances from the peritubular capillaries into the nephron tubule
31
renal excretion
into urine
32
when substances are reabsorbed, then enter the _______
peritubular capillaries
33
aldosterone
secreted by adrenal cortex and increases the reabsorption of Na+ and secretion of K+ by the distal tubule and collecting duct
34
anti-diuretic hormone/vasopressin
secreted by the posterior pituitary gland and increases the reabsorption water by the distal tubule and collecting duct
35
principle cells in the DT and CD are the cells that have _____ with ____ and _____
receptors, aldosterone, ADH
36
external urethral sphincter
voluntary control of opening and closing of urethra, skeletal muscle
37
internal urethral sphincter
involuntary opening and closing of urethra, smooth muscle
38
detrusor muscle
smooth muscle that contracts to push urine into urethra
39
micturition reflex
discharge of urine from the urinary bladder
40
micturition reflex: sensory
when bladder volume reaches certain level, sensory nerves send messages to the micturition center in the spinal cord
41
micturition reflex: motor
the parasympathetic NS causes contraction of the detrusor muscle and inhibition of the internal urethral sphincter and the somatic NS inhibits the external urethral sphincter
42
male urethras vs female urethras
5x longer in males divided into 3 segments in males but one short tube for females common duct for urinary and reproductive system in males, completely separate in females