Muscle Tissue Flashcards

1
Q

epimysium

A

dense irregular CT that separates muscle from surrounding tissue and organs and is connected to deep fascia

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2
Q

perimysium

A

divides muscle into series of internal compartments (fasicles)

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3
Q

endomysium

A

surrounds each skeletal muscle fiber; binds each muscle to its neighbor. satellite cells lie between endomysium

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4
Q

organization of skeletal muscle

A

skeletal muscle, fascicle, muscle fiber, myofibril, myofilaments

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5
Q

muscle fibers

A
  • called fibers because they’re long, run from origin to insertion, parallel to one another
  • contains muscle cell/fiber contains myofibrils
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6
Q

muscle fascicles

A

contain muscle cells/fibers, within the fascicle, all muscle fibers are parallel to one another, surrounding each muscle cell/fiber in the fascicle is endomysium made of reticular fibers

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7
Q

myofibrils

A

-contain the thick (myosin) and thin filaments arranged into sarcomeres

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8
Q

sarcomeres

A

Z-disc to Z-dic, parallel to each other and to the long axis of the muscle (origin to insertion)

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9
Q

thin filaments

A
  • attach to the Z-discs at the ends of the sarcomere

- composed of actin, troponin, and tropomyosin

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10
Q

troponin

A

binds to calcium, myosin can then bind to actin (forms a cross-bridge)

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11
Q

thick filaments

A

center of the sarcomere, composed of protein myosin, myosin head is what attaches to actin in the presence of calcium

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12
Q

anatomy of a sarcomere

A

A band: entire length of thick filaments, stains darker

I band: region that only includes thin filaments, stains lighter

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13
Q

sarcoplasmic reticulum

A
  • storehouse for calcium, when a muscle cells has an electric signal this calcium is released
  • increase in calcium is the sarcoplasm binds to troponin and allows for formation of cross-bridges
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14
Q

sliding filament mechanism

A
  • myosin binds to actin creating a cross-bridge between the two filaments
  • myosin head rotates towards the center of the sarcomere (power stroke) the power stroke pulls the thin filaments towards the center of the sarcomere
  • sarcomeres shorten (Z-discs move closer) and both the H-zone (only thick filaments) and the I-band decrease in size
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15
Q

neural innervation

A

-somatic motor neurons release acetylcholine (ACH) onto muscle fibers

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16
Q

acetylcholine

A

causes muscle cell to generate an electric signal (action potential) which causes the cell to release calcium and contract by the sliding filament mechanism

17
Q

neuromuscular junction

A

ACH released by the somatic motor neuron binds nicotinic receptors on the sarcolemma

18
Q

action potential

A

in response to ACH-nicotinic receptor binding leads to calcium release from the SR

19
Q

calcium release from SR

A

this calcium binds to troponin and allows for cross-bridges to form and the sliding filament mechanism to occur

20
Q

difference between muscle fiber types

A

vary in content of myoglobin, the speed at which they undergo the sliding filament mechanism, and how they produce ATP

21
Q

skeletal muscle fiber types

A
  • slow oxidative fibers (type I)
  • fast oxidative-glycolytic (type IIa)
  • fast glycolytic (type IIb)
22
Q

muscular dystrophy

A

the protein dystrophin connects thin filaments of the sarcomere to the membrane and is thought to transmit tension generated by muscle contraction to the tendon

23
Q

muscle origin

A

proximal and they are stationary during muscle contraction

24
Q

insertion

A

distal and they move during contraction

25
Q

reverse muscle action

A

muscle’s origin moves towards the insertion

26
Q

muscle contraction

A

muscle fibers contract and shorten and pull on the tendons

27
Q

tendons (aponeuroses)

A

act like the lines (sheets) that transmit the forces generated by muscle contraction

28
Q

patella

A

functions like a pulley that changes the direction of a force

29
Q

organization of skeletal fibers

A
  • longer the fibers in a muscle-greater the range of motion

- power of muscle depends on its cross-sectional area

30
Q

parallel muscle types

A

flat, fusiform, strap

31
Q

pennate muscles

A

-muscle with fascicles that attach obliquely to the tendon**generates the highest degree of force but sometimes a decrease in range of motion

32
Q

pennate muscle example

A

unipennate, bipennate, multipennate

33
Q

unipennate

A

fascicles on one side of tendon

34
Q

bipennate

A

fascicles on both sides of central tendon

35
Q

multipennate

A

fascicles at oblique angle from many directions to several tendons

36
Q

tendons in pennate muscles

A
  • one or more tendons run through the body of the muscle

- multi-pennate muscels have versatility by using different portions of the muscle

37
Q

primary action

A
  • prime mover or agonist
  • synergist: assists the prime mover
  • antagonist: action that opposes the agonist
38
Q

naming of skeletal muscles

A

shape, size, location, attachment, number of origins, orientation of fibers, action

39
Q

other functions of msucles

A

support for soft tissue, form sphincters and encircle openings