Muscle Tissue Flashcards

1
Q

epimysium

A

dense irregular CT that separates muscle from surrounding tissue and organs and is connected to deep fascia

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2
Q

perimysium

A

divides muscle into series of internal compartments (fasicles)

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3
Q

endomysium

A

surrounds each skeletal muscle fiber; binds each muscle to its neighbor. satellite cells lie between endomysium

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4
Q

organization of skeletal muscle

A

skeletal muscle, fascicle, muscle fiber, myofibril, myofilaments

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5
Q

muscle fibers

A
  • called fibers because they’re long, run from origin to insertion, parallel to one another
  • contains muscle cell/fiber contains myofibrils
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6
Q

muscle fascicles

A

contain muscle cells/fibers, within the fascicle, all muscle fibers are parallel to one another, surrounding each muscle cell/fiber in the fascicle is endomysium made of reticular fibers

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7
Q

myofibrils

A

-contain the thick (myosin) and thin filaments arranged into sarcomeres

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8
Q

sarcomeres

A

Z-disc to Z-dic, parallel to each other and to the long axis of the muscle (origin to insertion)

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9
Q

thin filaments

A
  • attach to the Z-discs at the ends of the sarcomere

- composed of actin, troponin, and tropomyosin

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10
Q

troponin

A

binds to calcium, myosin can then bind to actin (forms a cross-bridge)

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11
Q

thick filaments

A

center of the sarcomere, composed of protein myosin, myosin head is what attaches to actin in the presence of calcium

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12
Q

anatomy of a sarcomere

A

A band: entire length of thick filaments, stains darker

I band: region that only includes thin filaments, stains lighter

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13
Q

sarcoplasmic reticulum

A
  • storehouse for calcium, when a muscle cells has an electric signal this calcium is released
  • increase in calcium is the sarcoplasm binds to troponin and allows for formation of cross-bridges
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14
Q

sliding filament mechanism

A
  • myosin binds to actin creating a cross-bridge between the two filaments
  • myosin head rotates towards the center of the sarcomere (power stroke) the power stroke pulls the thin filaments towards the center of the sarcomere
  • sarcomeres shorten (Z-discs move closer) and both the H-zone (only thick filaments) and the I-band decrease in size
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15
Q

neural innervation

A

-somatic motor neurons release acetylcholine (ACH) onto muscle fibers

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16
Q

acetylcholine

A

causes muscle cell to generate an electric signal (action potential) which causes the cell to release calcium and contract by the sliding filament mechanism

17
Q

neuromuscular junction

A

ACH released by the somatic motor neuron binds nicotinic receptors on the sarcolemma

18
Q

action potential

A

in response to ACH-nicotinic receptor binding leads to calcium release from the SR

19
Q

calcium release from SR

A

this calcium binds to troponin and allows for cross-bridges to form and the sliding filament mechanism to occur

20
Q

difference between muscle fiber types

A

vary in content of myoglobin, the speed at which they undergo the sliding filament mechanism, and how they produce ATP

21
Q

skeletal muscle fiber types

A
  • slow oxidative fibers (type I)
  • fast oxidative-glycolytic (type IIa)
  • fast glycolytic (type IIb)
22
Q

muscular dystrophy

A

the protein dystrophin connects thin filaments of the sarcomere to the membrane and is thought to transmit tension generated by muscle contraction to the tendon

23
Q

muscle origin

A

proximal and they are stationary during muscle contraction

24
Q

insertion

A

distal and they move during contraction

25
reverse muscle action
muscle's origin moves towards the insertion
26
muscle contraction
muscle fibers contract and shorten and pull on the tendons
27
tendons (aponeuroses)
act like the lines (sheets) that transmit the forces generated by muscle contraction
28
patella
functions like a pulley that changes the direction of a force
29
organization of skeletal fibers
- longer the fibers in a muscle-greater the range of motion | - power of muscle depends on its cross-sectional area
30
parallel muscle types
flat, fusiform, strap
31
pennate muscles
-muscle with fascicles that attach obliquely to the tendon**generates the highest degree of force but sometimes a decrease in range of motion
32
pennate muscle example
unipennate, bipennate, multipennate
33
unipennate
fascicles on one side of tendon
34
bipennate
fascicles on both sides of central tendon
35
multipennate
fascicles at oblique angle from many directions to several tendons
36
tendons in pennate muscles
- one or more tendons run through the body of the muscle | - multi-pennate muscels have versatility by using different portions of the muscle
37
primary action
- prime mover or agonist - synergist: assists the prime mover - antagonist: action that opposes the agonist
38
naming of skeletal muscles
shape, size, location, attachment, number of origins, orientation of fibers, action
39
other functions of msucles
support for soft tissue, form sphincters and encircle openings