Unit 17 Flashcards
what percent of pts with ovarian ca have mets at dx
75 percent
what does the malignancy mimick in ovo ca
action of normal ovary
which cancer is the most lethal reprod ca
ovarian
et of ovarian ca
gene mutation
4 risks of ovarian ca
ageing
autosomal dominant inherited forms
family hx
other
aging as a risk fator
inc in ages 65-84 yo. inc ovulatory age -> inc risk dt exposure
what other reasons are risks for bc
nulliparity
infertility
dysmennorhea
what 3 areas does OC arise
epithelial (90)
germ cell
stromal tumour
what strs does OC affect via extension and invasion
tubes
uterus
ligaments,
other ovary v
what strs does OC affect bia seeding
bowel, mesentary, liver, peritoneum
late mnfts of OC
abdm distention related to inc size of tumor causing p on other strs
papillation
tiny tumors inside/on ovary with different shapes and sizes (primary ovary tumors)
early mnfts of OC
none
what non spec GI mnfts may occur in OC
flatulence, GI discomofrt, abdm distention
what GU mnfts mah occur in OC
pain, urinary or bowel bobstr
what mnfts of OC may affect the abdm cavity
ascites and dyspnea
what mnft may lead to US and exploratory sx
pelvic mass
tx for OC
aggressive tx. combo of sx and chemo
when is a lapratomy done in OC
6-24m
what is the most common reprod ca in women
uterine ca
when does UC peak
55-65 yo
Et for uc
hyperestroginsm
family hx
some cases may be E independent
risks for uc 7
obesity age excessive pelvic radiation hx or family hx of a reprod ca DM htn inc e with dec P
why is obesity a risk factor for uc
adipose tissue retains and produces E
what type of carcinoma is usually in UC
adenocarcinoma
patho of UC
normal hyperplasia -> inc E -> dysplasia ->ana plasia
2 types of UC
type 1 and type 2