Unit 17

Question 1

what percent of pts with ovarian ca have mets at dx

Answer 1

75 percent

Question 2

what does the malignancy mimick in ovo ca

Answer 2

action of normal ovary

Question 3

which cancer is the most lethal reprod ca

Answer 3

ovarian

Question 4

et of ovarian ca

Answer 4

gene mutation

Question 5

4 risks of ovarian ca

Answer 5

ageing
autosomal dominant inherited forms
family hx
other

Question 6

aging as a risk fator

Answer 6

inc in ages 65-84 yo. inc ovulatory age -> inc risk dt exposure

Question 7

what other reasons are risks for bc

Answer 7

nulliparity
infertility
dysmennorhea

Question 8

what 3 areas does OC arise

Answer 8

epithelial (90)
germ cell
stromal tumour

Question 9

what strs does OC affect via extension and invasion

Answer 9

tubes
uterus
ligaments,
other ovary v

Question 10

what strs does OC affect bia seeding

Answer 10

bowel, mesentary, liver, peritoneum

Question 11

late mnfts of OC

Answer 11

abdm distention related to inc size of tumor causing p on other strs

Question 12

papillation

Answer 12

tiny tumors inside/on ovary with different shapes and sizes (primary ovary tumors)

Question 13

early mnfts of OC

Answer 13

none

Question 14

what non spec GI mnfts may occur in OC

Answer 14

flatulence, GI discomofrt, abdm distention

Question 15

what GU mnfts mah occur in OC

Answer 15

pain, urinary or bowel bobstr

Question 16

what mnfts of OC may affect the abdm cavity

Answer 16

ascites and dyspnea

Question 17

what mnft may lead to US and exploratory sx

Answer 17

pelvic mass

Question 18

tx for OC

Answer 18

aggressive tx. combo of sx and chemo

Question 19

when is a lapratomy done in OC

Answer 19

6-24m

Question 20

what is the most common reprod ca in women

Answer 20

uterine ca

Question 21

when does UC peak

Answer 21

55-65 yo

Question 22

Et for uc

Answer 22

hyperestroginsm
family hx
some cases may be E independent

Question 23

risks for uc 7

Answer 23

obesity
age
excessive pelvic radiation
hx or family hx of a reprod ca
DM
htn
inc e with dec P

Question 24

why is obesity a risk factor for uc

Answer 24

adipose tissue retains and produces E

Question 25

what type of carcinoma is usually in UC

Answer 25

adenocarcinoma

Question 26

patho of UC

Answer 26

normal hyperplasia -> inc E -> dysplasia ->ana plasia

Question 27

2 types of UC

Answer 27

type 1 and type 2

Question 28

what percent of UC is type 1 UC

Answer 28

90

Question 29

Which type of UC is E dependent/sensitive

Answer 29

type 1

Question 30

which type of UC has good prognosis

Answer 30

type 1

Question 31

in which UC does endometrial hyperplasia ocur

Answer 31

type 1

Question 32

what percent of cases are type 2 UC

Answer 32

10 percent

Question 33

what is type 2 uc associated with

Answer 33

atrophy of endometrium

Question 34

which type of UC has poorer prognosis

Answer 34

2

Question 35

what type of progresion does UC have

Answer 35

slow

Question 36

where does UC extend to

Answer 36

myometrium, vagina

Question 37

how does UC met (late)

Answer 37

lymph and blood

Question 38

mfnts of UC

Answer 38

endometrial bleeding inbetween periods and prolonged. mnfts rt spread

Question 39

tx of UC

Answer 39

based on stage | sx c radiation

Question 40

what percent of cervical ca is avoidable

Answer 40

100

Question 41

what percent of cervical ca is curable in situ

Answer 41

100

Question 42

how long is the preca stage of cervical ca

Answer 42

2 years

Question 43

risks of CCA

Answer 43

HPV smoking hx of stds

Question 44

how many strains of hpv are there? what percent of them are sexually transmitted

Answer 44

100 | 40

Question 45

what strains of HPV are most concerning

Answer 45

6,11,16,18

Question 46

what do hpv strains 6/11 cause

Answer 46

90% genital warts

Question 47

what do hpv strains 16/18 cause

Answer 47

70% cervical ca

Question 48

who has increased risk of sexual transmissin of hpv strains 6,11,16,18

Answer 48

early aged sex and numerous partners

Question 49

origin of CCA

Answer 49

squamous cell

Question 50

how does cca originate

Answer 50

as dysplasia (preca lesion)

Question 51

what is it called when cca moves into the epith layer

Answer 51

carcinoma in situ

Question 52

what is it called when cca moves into deeper layers

Answer 52

invasive ca

Question 53

characteristics of invasive cca spread

Answer 53

spreads in and out in a cone shape

Question 54

pap smear

Answer 54

slough off of exfoliating cells that are stained and look for dysplasia

Question 55

what do positive pap smears have

Answer 55

a CIN and a number

Question 56

what does CIN stand for

Answer 56

cervical intraepitheal neoplasia

Question 57

CIN1

Answer 57

mikd dysplasia pre ca

Question 58

cin2

Answer 58

mod dysplasia pre ca

Question 59

cin 3

Answer 59

sev dysplasia and carcinoma in siut

Question 60

how does cca met

Answer 60

via lymph

Question 61

what do you do if your pap is positive

Answer 61

repeat test

Question 62

dx for cca

Answer 62

pap | coloscopy

Question 63

mfnts of cca

Answer 63

vaginal dc and bleeding bet menses mettorrhagia inc freq and lenghth of menses late sign: pain

Question 64

tx of cca (early)

Answer 64

excision

Question 65

tx of cca (late)

Answer 65

excision and radiation | radical hysterectomh

Question 66

types of excsion for cca

Answer 66

crytosx conization laser

Question 67

crytosx

Answer 67

induce cell necrosis via freezing

Question 68

conization sx

Answer 68

remove cone shaped piece

Question 69

laser sx

Answer 69

necrosis via heat