Unit 11

Question 1

lung ca

Answer 1

rt death by disease, mostly avoidable

Question 2

mortality of lung ca

Answer 2

30%

Question 3

characteristics of lung c

Answer 3

aggressive, invasive, metastic

Question 4

where does lung c met to

Answer 4

brain, bones ,liver

Question 5

4 primary types of lung ca

Answer 5

adenocarcinoma
squamous cell carcinoma
large cell carcinoma
small cell carcinoma

Question 6

2 cats of primary lung ca

Answer 6

1 - not small cell lung ca

2 - small cell lung ca

Question 7

what ca’s are in nsclc

Answer 7

adenocaracino
squamous cell carcinoma
large cell carcinoma

Question 8

what cas are in sclc

Answer 8

small cell carcinoma

Question 9

what is the 5th type of primary lung ca

Answer 9

mixed group

Question 10

what percent of lug ca is adenocarcinoma

Answer 10

30

Question 11

what percent of lung ca is squamous cell carcinoma

Answer 11

30

Question 12

what percent of lung ca is large cell carcinoma

Answer 12

12

Question 13

what percent of lung ca is small cell carcinoma

Answer 13

22

Question 14

et of lung ca

Answer 14

smoking (80)
toxins (eg asbestos)
genetic predisposition

Question 15

where does 95% of lung ca originate

Answer 15

bronchi

Question 16

where does squamous cell carcinoma originate

Answer 16

hilum of central bronchi

Question 17

where does squamous cell carcinoma spread

Answer 17

regionally to hilar nodes

Question 18

who has increased dispostion to squamous cell carcinoma

Answer 18

men

Question 19

what may tumor spread of squamous cell carcinoma cause

Answer 19

impact to pericardium -> dec heart fx

Question 20

where does adenocarcinoma originate

Answer 20

peripherary

Question 21

what is adenocarcinoma assoc with

Answer 21

alveoli and bronchioles

Question 22

who has an increase in adenocarcinoma

Answer 22

women, non smokers

Question 23

where does large cell carcinoma originate

Answer 23

peripheray

Question 24

characteristics of large cell carcinoma

Answer 24

large, undifferentiated cells

mets early

Question 25

which ca out of all nsclc has poorest prognisis

Answer 25

large cell carcinoma

Question 26

characteristic of cells in small cell carcinoma

Answer 26

small, oval, oat like cells

Question 27

which population experiences an increase in small cell carcinoma

Answer 27

99% smokers

Question 28

characteristics of small cell carcinoma

Answer 28

aggressive, invasive with slim prognosis

Question 29

where does small cell carcinoma met to early

Answer 29

brain

Question 30

what percent of small cell carcinoma has mets at dx

Answer 30

70

Question 31

what does small cell carcinoma do to local tissue

Answer 31

invades quickly

Question 32

what is said about excision of small cell carcinoma

Answer 32

hard to excise, not resectable, cells may not be massed together

Question 33

what tx does small cell carincoma have inc response to

Answer 33

radiation, said to be radiosensitive

Question 34

what is a commone SE of small cell carcinoma

Answer 34

paraneoplastic syndrome

Question 35

what conditions are included in paraneoplastic syndrome

Answer 35

SIADH (adh) | cushings (cortisol, adrenocortico)

Question 36

what are mnfts of all lung ca's based on

Answer 36

type, site, ext of local invasion, mets

Question 37

central mnfts of lung ca

Answer 37

large aw obst, impaired breathing, unexplained coughing, wheezing, dyspnea

Question 38

other mnfts of lung ca

Answer 38

paraneoplastic syndrome hemoptysis pain cardiac mnfts

Question 39

hemoptysis

Answer 39

coughing blood rt vessel damage caused by malignancy

Question 40

cardiac mnfts in lung ca

Answer 40

rt inc P on heart. tumor has to affect pericardium, central malignancy only

Question 41

dx for lung ca

Answer 41

``` hx, px rule out URT, CLD cxr, CT, US, MRI bronchophy/needle biopsy sputum analysis/ bronchiol wash ```

Question 42

what is tx for lung ca basedo n

Answer 42

type

Question 43

tx for nsclc

Answer 43

sx, radiation, chemo

Question 44

tx for sclc

Answer 44

chemo radiation

Question 45

why does lung ca have poor prognosis

Answer 45

no good screen -> dec detection