Ubiquination and protein degradation

Question 1

Mono Ubiquitination

Answer 1

Trafficking endocytosis; gene expression/silencing

Question 2

K11 ubiquitination

Answer 2

protein degradation

Question 3

K48 ubiquitination

Answer 3

protein degradation by the proteasome

Question 4

K63 ubiquitination

Answer 4

DNA damage tolerance; kinase activation; trafficking; translation (non-proteolytic)

Question 5

K0 ubiquitination

Answer 5

inflammatory responsel

Question 6

SUMO

Answer 6

ubiquiting like protein that is important for gene expression and protein targeting; also may control degradation by competing with ubiquitin for binding sites.