Cooperative binding b-interferon gene

Question 1

HMGA1

Answer 1

binds first to DNA and de-kinks DNA (opens it up)

Question 2

Process

Answer 2

1) HMGA1 binds to DNA and opens it up 2) NF-kB, IRF, JUN, ATF bind to sequence 3) Acetyl transferases modify promoter sequence 4) now general transcription factors