DNA methylation mediated gene silencing Flashcards
1
Q
Process
A
1) MeCp2 binds to methylated DNA
(CPG islands) 2) MeCp2 recruits sin3A (histone deacetylase) 3) leads to silencing
2
Q
Sin3A
A
histone deacetylase
Biochemistry 431 > DNA methylation mediated gene silencing > Flashcards
Process
1) MeCp2 binds to methylated DNA
(CPG islands) 2) MeCp2 recruits sin3A (histone deacetylase) 3) leads to silencing
Sin3A
histone deacetylase