exam 3 paper

Question 1

D7

Answer 1

alternative SMN protein; produced by C-T base exchange at nucleotide 840; readily degraded

Question 2

SMN-C3

Answer 2

effective in increasing SMN proteins and disabling SMN2 truncation; upregulated DNAPN; PAP; effects exon 7 splice junction.

Question 3

Question

Answer 3

The mutation only causes truncation?; Any difference in the protein without the excision of exon 7?: Does SMN2 have less specificity?;