Type I Diabetes Flashcards
Role of delta cells secreted by the pancreas
secretes somatostatin which suppresses insulin and glucagon release
Insulin starts as ___ ___ insulin, gets reduced to ___ insulin, then finally gets cleaved to insulin and ___ __
prepro; pro; peptide C
Glucose is the most potent stimulant of insulin release but __ and ___ work too
fat; proteins
The __ (_ system) stimulates insulin while the __ system inhibits it
vagus (PS); sympathetic
What is the cephalic phase in regards to insulin release
the sight/smell of food can cause insulin release
Insulin is a major ___ hormone
anabolic
Reason for glucose in urine in diabetics
kidneys ability to reabsorb glucose overwhelmed
Vaginal ____ is common in diabetic women
candidiasis
Peak age of onset for type I diabetes is
5-7
What season is onset most likely in
winter
A sensitive autoantibody in Type I DM is
glutamic acid decarboxylase
This cation is an antigen for type I DM
Efflux zinc transporter (ZnT8)
This disease can masquerade as non-obese type II diabetes and can be controlled by diet/glucose pills
Latent autoimmune diabetes of adulthood
A parent with __ __ is a risk factor for type I
hashimoto’s thyroiditis
Best way to reverse DKA
insulin