Txt MI: Cardiac Arrest

Question 1

What is the effect of β₁ agonism in cardiac tissue during cardiac arrest?

Answer 1

Increased SNS activity of SA node, inducing myocardial systole (contractions + chronotropy)

This refers to the increase in heart rate and strength of contractions due to sympathetic nervous system activation.

Question 2

What type of drug is Epinephrine?

Answer 2

Non-selective adrenergic agonist

It stimulates α₁, α₂, β₁, and β₂ receptors.

Question 3

What are the effects of Epinephrine?

Answer 3

Increases heart rate, contractility, and induces vasoconstriction

Used in cardiac arrest and anaphylaxis.

Question 4

What are the potential side effects of Epinephrine?

Answer 4

Arrhythmias, hypertension, increased myocardial oxygen demand

Use with caution in ischemic heart disease.

Question 5

What type of drug is Isoproterenol?

Answer 5

Non-selective β agonist

It activates β₁, β₂, and β₃ receptors.

Question 6

What are the primary effects of Isoproterenol?

Answer 6

Increases heart rate and contractility

It is used for severe bradycardia and occasionally in arrest management.

Question 7

What are the side effects of Isoproterenol?

Answer 7

Tachycardia, arrhythmias, hypotension

Careful monitoring of hemodynamics is necessary.

Question 8

Fill in the blank: Increased SNS activity leads to the spread of _______ in heart tissue.

Answer 8

necrosis

This refers to the damage and death of heart tissue due to insufficient blood supply.