Categories And Drug names Flashcards
Name 4 direct acting cholinomimetics
Bethanecol (Musc CR agonist)
Pilocarpine (Musc CR agonist)
Nicotine (Nn CR agonist)
Varenicline (Nn CR partial agonist)
Name 4 indirect acting cholinomimetics
neostigmine ACHase inhibitor
donepezil ACHase inhibitor
Sarin ACHase irreversible inhibitor
parathione ACHase irreversible inhibitor
Name 4 direct acting cholinolytics
atropine “anticholinergic” or Muscarinic antagonist
scopolamine Muscarinic antagonist
solifenacin (Vesicare) selective m3 cholinergic receptor antagonist
tolterodine Muscarinic antagonist
Name 5 drugs in the Skeletal muscle relaxants/ antispastic category
(Also what nervous system do these work in)
baclofen GABA receptor agonist
pancuronium: non-depolarizing muscle relaxant/ nicotinic M (Nm) receptor antagonist
succinylcholine: depolarizing muscle relaxant/Nm receptor agonist
botulinum toxins: ACh release inhibitor (at NMJ)
dantrolene: “Inhibitor of Ca²⁺ release; muscle relaxant”
Name 2 Modulators of catecholamine biosynthesis
methyl-tyrosine Tyrosine hydroxylase inhibitor
L-Dopa Dopamine precursor
Name 2 Enhancers of sympathetic outflow
selegiline MAO-B inhibitor
tolcapone (Tasmar) COMT inhibitor
Name 3 Generalized Sympatho- mimetics
epinephrine nonselective a1,2 and b1,2 AR agonist
dopamine nonselective Catecholamine agonist
norepinephrine nonselective Catecholamine agonist
Name 3 Selective α AR Sympatho- mimetics
phenylephrine selective A1 agonist
tetrahydrozoline selective A1 AR agonist
clonidine selective a2 AR agonist
Name 5 Selective β AR Sympatho- mimetics
isoproterenol “B1 and 2 agonist; Non-selective β agonist”
dobutamine Selective B1 AR agonist
albuterol selective B2 agonist
terbutaline selective B2 agonist
mirabegron selective B3 AR agonist
Name 5 Indirect and Mixed-Acting Sympatho- mimetics
Amphetamine (Adderall) Indirect sympathomimetic/ stimulant
Dextroamphetamine (Dexedrine) Indirect sympathomimetic/ stimulant
Methylphenidate (Ritalin) “Indirect sympathomimetic/ stimulant”
Atomoxetine (Strattera®) NE reuptake inhibitor (NRI/NERI)
Ephedrine indirect acting sympathomimetic and weak a1 and b2 AR agonist (mixed actions)
Name 3 Selective α AR Sympatholytics
Phentolamine Non-selective α antagonist
Prazosin α1 antagonist
Tamsulosin α1A antagonist
Name 2 Selective β AR Sympatholytics
propranolol generalized/ Non-selective beta blocker B AR antagonist
metoprolol selective B1 AR receptor antagonist
Name 1 Combined/Generalized Sympatholytic
labetalol both A and B antagonist
Name 2 Cardiac Natriuretic Peptides
ANP Natriuretic peptide
BNP Natriuretic peptide
Name 2 Endothelial Factors
Endothelin Peptide vasoconstrictor
Nitric Oxide (NO) Gaseous signaling molecule
Name 6 players in Renin-Angiotensin-Aldosterone System (RAAS)
Renin Proteolytic enzyme hormone
Angiotensinogen Precursor protein hormone
Angiotensin I Inactive peptide precursor
Angiotensin II Active vasoconstrictor peptide
Angiotensin Converting Enzyme (ACE) Enzyme (peptidase)
Aldosterone Mineralocorticoid hormone
Name 2 Hypothalamic-Pituitary Hormones & Others that are important to RAAS
Anti-diuretic Hormone (ADH)- Peptide hormone
Bradykinin- Peptide mediator
Name 5 Adrenergic Anti- hypertensives
Propranolol Non-selective β blocker
Metoprolol Selective β₁ blocker
Prazosin α₁ blocker
Clonidine Central α₂ agonist
Methyl-DOPA “False neurotransmitter agent/methylated-structural analog of Dopa/sympatholytic by eventually stim α₂ agonist
Name 6 Diuretic Anti- hypertensives
hydrochlorothiazide thiazide diuretic
furosemide loop diuretic
amiloride Potassium-sparing diuretics
Eplerenone aldosterone antagonist (K+ sparing)
acetazolamide Carbonic anhydrase inhibitors
mannitol Osmotic diuretics
Name 6 Direct acting vasodilators
prazosin selective a1 AR antagonist
verapamil calcium channel blockers
hydralazine K+ channel and myosin light chain phosphatase (myosin LC Ptase) activator
Nitric Oxide guanylyl cyclase, myosin LC Ptase activator
Nitroprusside Guanylate cyclase activator
Minoxidil K+ channel activator
Name 3 ACE System Inhibitors (RAAS inhibitors)
Aliskiren Renin inhibitor
Captopril ACE inhibitor
Losartan Angiotensin II receptor blocker (ARB)
Name 2 Novel Antihypertensive Agents
Nesiritide BNP analog
Bosentan Endothelin receptor antagonist
Name 2 Drug Treatment of Angina Pectoris
Propranolol Non-selective β antagonist
Nitroglycerin “Nitrate (NO donor) arterial and venous vasodilator”
Name 2 drugs to stim SNS activity during arrest/peri-arrest
Epinephrine Non-selective adrenergic agonist
Isoproterenol Non-selective β agonist
Name 4 drugs to txt or decrease necrosis in MI
Propranolol Non-selective β blocker
tPA (Tissue Plasminogen Activator) Fibrinolytic agent
Urokinase Fibrinolytic agent
Streptokinase Fibrinolytic agent
Name 1 dysrhythmic
Amiodarone Class III antiarrhythmic (K⁺ channel blocker)
For Heart Failure, name 10 drugs that are useful
Captopril ACE inhibitor
Losartan Angiotensin Receptor Blocker (ARB)
Hydrochlorothiazide (HCTZ) Thiazide diuretic
Furosemide Loop diuretic
Eplerenone Aldosterone antagonist (K⁺ sparing)
Tolvaptan Vasopressin (V2) receptor antagonist
Metoprolol Selective β₁ blocker
Ivabradine (Corlanor) “If channel inhibitor
Na+/K+ channel blocker”
Digoxin Cardiac glycoside
Entresto (Sacubitril/Valsartan) Neprilysin inhibitor/ARB combination
Name 4 Antiplatelet drugs
Aspirin COX inhibitor
Clopidogrel (Plavix) ADP receptor antagonist
Tirofiban (Aggrastat) GPIIb/IIIa antagonist
Vorapaxar (Zontivity) PAR-1 receptor inhibitor
Name 3 Anticoagulants
Heparin Antithrombin activator (Indirect thrombin inhibitor)
Warfarin Vitamin K antagonist
Dabigatran (Pradaxa) Direct thrombin inhibitor
Name 7 drugs that treat hypercholesterolemia/HLD
Lovastatin HMG-CoA reductase inhibitor
Gemfibrozil Hepatic triglyceride inhibitor (Fibrate)
Niacin triglyceride lipase inhibitor
Cholestyramine “Bile acid sequestrant/
ion exchange resin”
Ezetimibe Cholesterol transport inhibitor
Vytorin (Ezetimibe + Simvastatin) Combination of cholesterol absorption inhibitor and statin
Evolocumab (Repatha) PCSK9 inhibitor (monoclonal antibody)
