Selective β AR Sympatholytics Flashcards
What type of drug is propranolol?
Generalized/non-selective beta blocker
B AR antagonist
What receptors does propranolol block?
Blocks β1 and β2 receptors
What are the therapeutic uses of propranolol?
- HTN
- Migraines
- Stress-related HTN
What is a significant caution when using propranolol?
Contraindicated in asthma patients due to bronchoconstriction
What are common side effects of propranolol?
- Bradycardia
- Fatigue
- Bronchospasm
What should be monitored when a patient is on propranolol?
Heart rate and pulmonary status
What type of drug is metoprolol?
Selective B1 AR receptor antagonist
What receptors does metoprolol block?
Blocks β1 receptors
What are the therapeutic uses of metoprolol?
- HTN
- Cardiac arrhythmias
- Ischemic heart disease
What is a significant feature of metoprolol compared to propranolol?
Cardioselective
What are common side effects of metoprolol?
- Bradycardia
- Hypotension
- Fatigue
What should be used with caution in patients taking metoprolol?
Patients with conduction disturbances
What is the MoA of metoprolol?
Blocks β1 receptors to decrease heart rate and myocardial contractility
What is the Moa of propranolol?
Blocks β1 and β2 receptors, reducing heart rate and contractility
