Trematodes II Flashcards
What are the DH of Paragonimus kellicotti?
Dogs Cats Pigs Muskrats Mink Wild/domestic carnivores Occasionally humans
What is the 1st IH of Paragonimus kellicotti?
Aquatic snails
What is the 2nd IH of Paragonimus kellicotti?
Crayfish
What is the PH of Paragonimus kellicotti?
Rodents
What is the DH site of Paragonimus kellicotti?
Lung parenchyma (encysted)
What is the life cycle of Paragonimus kellicotti?
DH ingests crayfish with mature metacercariae or PH
Excyst in SI, penetrates gut to peritoneal cavity to diaphragm to lungs
Form cysts in lung parenchyma; mature to adults
Egg pass from cyst to bronchi
Eggs coughed up and swallowed
Unembryonated eggs in feces
Miracidia hatch; penetrate aquatic snail
Cercariae emerge; enter crayfish
Metacercariae form
What causes pathology with Paragonimus kellicotti?
Migrating flukes
How can Paragonimus kellicotti eggs be diagnosed?
Fecal sedimentation (preferred) or flotation
How can Paragonimus kellicotti adults be diagnosed?
Radiographs (pulmonary cysts)
Necropsy
Can Paragonimus kellicotti infect humans?
Yes, by eating undercooked/raw crayfish
What is Paragonimus westermani in humans?
Oriental lung fluke
What is the DH of Nanophyetus salmincola?
Raccoon Mink Fox Coyote Dog Cat Piscivorous birds Piscivorous mammals Humans (rare)
What is the 1st IH of Nanophyetus salmincola?
Aquatic snails
What is the 2nd IH of Nanophyetus salmincola?
Fish
Salmon
What is the DH site of Nanophyetus salmincola?
Small intestine
What is the 2nd iH site of Nanophyetus salmincola?
Kidneys, muscle, fins, other organs
What is the life cycle of Nanophyetus salmincola?
DH ingests fish with metacercariae
Develop to adults in SI; NO extra-intestinal migration
Unembryonated eggs passed in feces
Miracidia hatch; infect awautic snail
Cercariae emerge from snail
Cercariae penetrate young fish
Metacercariae form in kidneys, muscle, fins
What causes pathology in the fish IH with Nanophyetus salmincola?
Metacercariae
What causes pathology in the canine DH with Nanophyetus salmincola?
Adults
What is the pathology in canine DH with Nanophyetus salmincola?
Neorickettsia helminthoeca: “salmon-poisoning disease”
How can Nanophyetus salmincola eggs be diagnosed?
Sedimentation/fecal flotation
Do Nanophyetus spp cause human infections?
Yes, but it is rare
Cause “fish flu”
What is the DH of Alaria spp?
Cats
Dogs
Wide range of carnivores
What is the 1st IH of Alaria spp?
Aquatic snails
What is the 2nd IH of Alaria spp?
Tadpoles
What is the PH of Alaria spp?
Frogs
Snakes
Mice
Mammals
What is the site of Alaria spp in DH?
Small intestine or mammary glands in lactating cat
What is the Alaria spp life cycle? *indicate bolded in lecture
DH ingests infected tadpole or PH with mesocercariae
Migration to diaphragm to lungsl develop into metacercariae; coughed up trachea, down esophagus to SI or in lactating cat: mesocercariae migrate to mammary gland
Developes to adults in SI or remain mesocercariae- transmammary (nursing kitten)
Unembryonate eggs in feces
Miracidia hatch; infect aquatic snail
Cercariae emerge in water
Cercariae penetrate tadpole; develop into mesocercariae
What happens with transmammary transmission of Alaria spp in the lactating cat?
Mesocercariae migrate to mammary glands
What is the pathology of Alaria spp in cat DH?
Attached to mucous membrane of SI
Usually little harm
Migratory tracts through lung
How can you diagnose Alaria spp eggs?
Fecal sedimentation
What Alaria species causes human infections?
Alaria americana
What is Potomac Horse Fever?
Equine Neorickettsiosis
What serves as a reservoir for Potomac Hose Fever?
Digenetic trematodes (Acanthatrium oregonense)
What is the infectious agent for Potomac Horse Fever?
Neorickettsia risticii
What is the DH of Acanthatrium oregonense?
Bats
What is the aaberrant hosts of Acanthatrium oregonense?
Equine
How do horses get Potomac Horse Fever?
Ingest mayfly with metacercariae harboring Neorickettsia risticii
What is the DH of Heterobilharzia americana?
Raccoons (natural DH) Dogs** Bobcats Nutria Opossum Florida panther Beaver Horses Llama Other mammals
What is the IH of Heterobilharzia americana?
Lymnaeid snails
What is the DH site of Heterobilharzia americana?
Hepatic portal and mesenteric veins
What is Heterobilharzia americana the causative agent of?
Canine schistosomiasis
What is the life cycle of Heterobilharzia americana?
Embryonated eggs shed in feces
Miracidia hatch in waterl infect a lymnaeid snail
Cercariae emerge and penetrate the skin of DH
Migration through lungs to the liver
Mature to adults
Adults migrate through portal veins to mesenteric veins
Eggs migrate through mesenteric veins and intestinal wall to lumen of intestine
What is the pathology in the canine Dh with Heterobilharzia americana?
Severe granulomatous inflammation in SI, liver, LI, pancreas
Fibrosis
Mineralization
Death
What is the pathology with Heterobilharzia americana induced by?
Eggs
How are Heterobilharzia americana eggs diagnosed?
Fecal sedimentation (saline)
What is the human infection caused by Heterobilharzia americana?
“Swimmer’s itch”
Cercarial dermatitis