Nematodes VI: Strongyloides Flashcards
What do the Strongyloides free living stages (L1 and L2) have?
Rhabditiform esophagus
What makes up the rhabditiform esophagus?
Bulb
Isthmus
Corpus
Describe the heterogonic life cycle
Free living life cycle L1 in eggs passed in feces L1 and L2 in feces Filariform larvae (L3) in contaminated soil Free-living male and female adults
Describe the homogonic life cycle
Filariform larvae (L3) are in contaminated soil and penetrate skin
—Infective L3 larvae
Parthogenesis
—parasitic females only (parasitic males do not exist)
—Clones of eggs
What is the percutaneous transmission route?
L3s penetrate skin –> circulatory –> lymphatic systems –> lungs –> alveoli –> migrate or coughed up and swallowed –> mature in SI
What is the peroral transmission route?
Penetrate oral mucosa and migrate as they do in percutaneous OR
Ingest infective L3; go directly to SI
What is the host of ransomi?
Swine
What is the route of infection for ransomi? What is the PPP for each?
Percutaneous* (7-10)
Peroral (7-10)
Transmammary** (4)
Transplacental (4)
Describe the percutaneous or peroral Strongyloides ransomi transmission route
Filariform larvae
Tracheal migration to maturation
Describe somatic migration of Strongyloides ransomi
Accumulate as arrested larvae
—Adipose tissues, especially mammary tissues
Where do mature gilts store Strongyloides ransomi larvae?
Adipose tissues
Where do mature gilts shed Strongyloides ransomi larvae?
Colostrum and milk
What is the key to epidemiology in swine with Strogyloides ransomi?
Transmammary
What is necessary to diminish larval development as well as multiplication of free-living generations of Strongyloide ransomi?
A high level of hygiene
What is the host of Strongyloides westeri?
Equids
What is the route of infection for Strongyloides weteri? What is the PPP of each?
Percutaneous (7-10)
Peroral (7-10)
Transmammary** (4)
What is the most important route of transmission for Strongyloides westeri?
Transmammary
When do foals shed Strongyloides westeri eggs?
10 to 14 days after birth
What are clinical signs of Strongyloides westeri?
Diarrhea (foal-heat)
What is the zoonotic potential of Strongyloides westeri?
Creeping eruption
—Allergic response to free-living L3 in humans
What is the host of Strogyloides papillosus?
Ruminants
What is the route of infection for Strongyloides papillosus? What is the PPP for each?
Percutaneous: primary route for sheep/goats (7-10)
Transmammary: primary route for cattle (6)
What is the technique of choice for diagnosing Strongyloides ransomi, westeri, and papillosus?
Fecal flotation
What are the adults of Strongyloides ransomi, westeri, and papillosus like?
Small (3-10 mm)
Embedded in SI mucosa
Generally need skin scraping of mucosa
How can you control Strongyloides ransomi, westeri, and papillosus?
Maintain clean, dry envrionment
What is the host of Strongyloides stercoralis?
Canids
What is the route of infection for Strongyloide stercoralis? What is the PPP?
Percutaneous (7-10)
Describe autoinfection with Strongyloides stercoralis
Rare
Tends to happen only if bitch is infected while lactating
Hyperinfection, or uncontrolled autoinfection is also rare
What are the different Strongyloides stercoralis third stage larvae?
Auto-infective third stage larvae (L3a)
Infective third stage larvae (L3i)
Describe L3a
Develop within intestine of dog
Invade dog through wall of large intestine
Describe L3i
Develop in environment
Invade dog through skin
How can you diagnose Strongyloide stercoralis?
L3a in lung of host
Blood filling alveolar space
L1 in feces of infected host
Technique of choice: Baermann
How can you diagnose Strongyloides sterocoralis adults?
Mucosal scraping Parasitic female (long esophagus)
What king of problem does strongyloides stercoralis tend to be?
Kennel problem
—Summer with hot/humid weather
What is the zoonotic potential of Stronglyoides stercoralis?
Cutaneous larva migrans
How can you control Strongyloides stercoralis?
Maintain clean, dry environment
What is the host of Strongyloides tumefaciens?
Felids
What is the route of infections for Strongyloides tumefaciens?
Percutaneous and Peroral
Life cycle is unknown
What is the clinical sign for Strongyloides tumefaciens?
Grossly visible tumor-like nodules in large intestine