Ectoparasites III- Other Tick-Borne Pathogens Flashcards
How long do most hard ticks attach and feed?
Days
Why do immature and adult female ticks take day to complete feeding/engorge?
They have an incomplete scutum
What is feeding like for soft ticks?
Feed quickly and often
Usually go back to same host repeatedly
What are methods of direct disease?
Tick bites
Paralysis (toxicosis)
…red meat allergy
What are methods of indirect disease?
Transmission of pathogens
- -viruses
- -bacteria
- -protozoa
What is the clinical presentation of direct disease from tick bites?
Pain and inflammation at site Possible complications (anemia, secondary infections, "tick worry")
What are methods of treatment and prevention for direct disease from tick bites?
Manual removal vs. acaricide
Year-round control
What is an example of a severe direct disease due to bites?
Dermacentor albipictus (Winter Tick) is a 1-host tick known for causing hair and blood loss primarily in moose
What is tick paralysis (direct disease) caused by?
Toxin in tick saliva
Often female hard ticks
Why do female ticks often cause tick paralysis?
They stay on longer
What are the tick species that can cause tick paralysis?
Argasid: Argas persicus
Ixodid: Dermacentor* variabilis, Ambylomma maculatum, A. americanum
What is the clinical presentation of tick paralysis?
Acute ascending flaccid paralysis
What is Red Meat Allergy?
Direct disease
Allergic reaction to pork, beef, lamb
Described in humans
IgE antibodies to galactose-α-1,3-galactose (α-gal)
What is galactose-α-1,3-galactose (α-gal)?
Oligosaccharide blood group component found in non-primate species
What are the 2 processes that that transmission via vectors can occur with indirect disease?
Biological transmission (most vector-borne diseases) with reproduction or developmental changes in pathogen Mechanical transmission without reproduction or developmental changes in pathogen
What makes a tick a good vector?
Persistent blood-feeder Wide host range Few natural enemies High reproductive potential Pathogen can be maintained in tick populations
What makes up the tick-host-pathogen system?
Vector competency
Reservoir host
What is vector competency?
Capable of acquiring, maintaining, and transmitting an infectious agent
What is a reservoir host?
Capable of acquiring, maintaining, and transmitting infectious agents
May be the vertebrate host or arthropod vector
What was the first described vector-borne disease?
Texas cattle fever (1893), Babesia/Rhipicephalus
What is the time line for the first VBD described?
1893: Texas cattle fever, Babesia/Rhipicephalus
1905: relapsing fever (Africa), Borrelia/Ornithodoros)
1906: Rocky mountain spotted fecer, Rickettsia/Dermacentor
Describe tick-borne encephalitis
Powassan Encephalitis:
Vector(s)- Ixodes spp.
Clinically affected: humans
Mainly midwestern, northeastern US; Canada
Describe tick-borne hemorrhagic disease
Nairobi sheep disease
Vector(s)- various hard tick species
Hemorrhagic gastroenteritis- small ruminants
Africa; Asia
Describe tick-borne systemic disease
African Swine Fever: Vector(s)- Ornithodoros Systemic hemorrhagic disease Domestic swine; warthogs- asymptomatic reservoirs Africa Colorado Tick Fever: Human cases
What are vectors of Lyme disease?
Ixodes scapularis (eastern US) Ixodes pacificus (western US)
What is the agent of Lyme disease?
Borrelia burgdorferi
What are the reservoir hosts for Lyme disease?
Rodents (white-footed mouse; reservoir for bacteria)
White-tailed deer (required host for tick only)
Where is Lyme disease commonly found?
Northeastern and north-central US
How do the most exposed dogs to Lyme disease appear?
Clinically normal