Cestodes I and II Flashcards
What are the characteristics of class Cestoda?
Acoelomates
Dorsoventrally flat chain of segments
Monoecious
Where are adult cestodes usually found?
DH small intestine (there are some exceptions)
Are adult cestodes usually pathogenic?
No
What are cestode segments?
Proglottids
What is the cestode body?
Strobila
What is the anterior end of the cestode?
Scolex
Describe the scolex
Holdfast organ
May have specialized attachment organs (acetabula/suckers, bothria, bothridia)
What type of life cycle do cestodes use?
Indirect
Is the DH of cestodes a predator or prey?
Predator
Is the IH of cestodes a predator or prey?
Prey
What is the general indirect life cycle of cestodes?
Proglottids with eggs in feces Eggs in environment ingested IH with metacestode (larval stage) in tissues IH ingested DH with cestode in SI
What are the 2 important cestode orders?
Cyclophyllidea
Diphyllobothriidea
What are the cestodes that fall under Cyclophyllidea?
Taenia spp Echinococcus spp Diplyidium caninum Moniezia sp Anoplocephala spp Paranoplocephala mamillana Thysanosoma sp Mesocestoides corti
What are the cestodes that fall under Diphyllobothriidea?
Sprimetra spp
Diphyllobothrium latum
What order are the true cestodes?
Cyclophyllidea
What order are the primitive cestodes?
Diphyllobothriidea
Describe true cestodes
Terrestrial life cycle
Cestode larvae require 1 IH, which are various vertebrates and invertebrates
Describe primitive cestodes
Aquatic life cycle
Cestode larvae require 2 IHs, the first is a copepod and the second is a fish or non-fish vertebrate
Describe the scolex of Cyclophyllidea
Suckers +/- hooks
Describe the eggs of Cyclophyllidea
Shed in gravid proglottids; eggs without operculum
What is the genital pore location in Cyclophyllidea?
Lateral
How many IH(s) are there for Cyclophyllidea?
1
Describe the larval stage of Cyclophyllidea
6 types
Describe the scolex of Diphyllobothriidea
Bothria (grooves)
Describe the eggs of Diphyllobothriidea
Shed from pore in proglottids; eggs operculate
What is the genital pore location in Diphyllobothriidea?
Medial (with uterine pore)
How many IH(s) are there for Diphyllobothriidea?
2
Describe the larval stage of Diphyllobothriidea
2 stages
What is a larval cestode in IH?
Metacestode
Which are more often associated with disease, metacestodes or adult cestodes?
Metacestodes
What do the 6 types of Cyclophyllidean larval stages depend on?
Species
Describe the 6 types of Cyclophyllidean larval stages
Metacestodes that develop into 1 adult in DH:
Cysticercus
Strobliocercus
Cysticercoid
Metacestodes that develop into multiple adults in DH:
Coenurus
Uniocular hydatid cyst
Alveolar (multiocular) hydatid
What are the 2 stages for Diphyllobothriideans?
Procercoid develops in 1st IH
Plerocercoid develops in 2nd IH
—-Each plerocercoid develops into 1 adult cestode
Describe cysticercus
“bladderworm”
Small, fluid-filled; scolex inside
e.g. taenia pisiforms
Develops into 1 adult
Describe strobilocercus
Fluid-filled bladder, but scolex everted
Taenia taeniaformis
Develops into 1 adult
Describe cysticercoid
Solid (vs bladder); scolex inside
Cestodes with arthropod IH
Dipylidium caninum, Anoplocephalids
Develops into 1 adult
Describe coenurus
Multiple larvae attached in cyst
Taenia multiceps
Develops into multiple adults
Describe uniocular hydatid cyst
Cysts in cysts; internal budding
Thick-walled; slow growing
Echinococcous granulosis
Develops into multiple adults
Describe alveolar (multiocualr) hydatid
External budding
Thin-walled; invasive; faster growht
Echinococcous multilocularis
Develops into multiple adults
What budding does unilocular hydatid cyst have?
Endogenous budding (slow growing; thick-walled)
What budding does mutliocular have?
Exogenous budding (fast growing; thin-walled)
What are the 2 genera of importance in the Cyclophyllidea family Taeniidae?
Taenia
Echinoccocus
What are the DH and IH of Taeniidae?
Mammals
Is the family Taeniidae zoonotic?
Yes, humans may be DH or dead-end IH
What is used to treat cestodes?
Praziquantel
Epsiprantel
Fenbendazole
NOT avermectins/milbemycins
What is the DH of Taenia pisiformis?
Canids
What is the IH of Taenia pisiformis?
Rabbit
What is the life cycle of Taenia pisiformis?
Cysticercus is digested by DH –> scolex embeds in SI mucose –> develops in adult
Proglottids shed in feces
Egg ingested by IH, hatches –> hexacanth embryo migrates to organ –> develops into cysticercus
What is the DH of Taenia hydatigena?
Canids
What is the IH of Taenia hydatigena?
Ruminants, swine
What is the life cylce of Taenia hydatigena?
Cysticercus is digested by DH –> scolex embeds in SI mucose –> develops in adult
Proglottids shed in feces
Cysticercus in peritoneal membranes of IH
Which Taenia is more common in common dogs?
T. pisiformis
What is the DH of Taenia taeniaeformis?
Felids
What is the IH of Taenia taeniaformis?
Rodents
What is the life cycle of Taenia Taniaeformis
Strobilocercus is digested by DH –> scolex embeds in SI mucosa –> develops into adult
Proglottids shed in feces
Strobilocercus in liver, peritoneum of IH
What is the PPP of Taenia pisiformia?
2 months
What is the PPP of Taenia hydatigena?
1.5 months
What is the PPP of Taenia taeniaformia?
1.5 months
Which Taenia spp are of public health importance? What are they found in?
Taenia solium: pork tapeworm
Taenia sagniata: beef tapeworm
What is the DH of Taenia solium?
Humans
What is the IH of Taenia solium?
Swine
Humans can become accidental IH
What is the life cycle of Taenia solium?
DH is humans
Proglottids shed in feces
Custicercus in muscle of IH
What is the DH of Taenia saginata?
Humans
What is the IH of Taenia sagniata?
Cattle
What is the life cycle of Taenia saginata?
DH is humans
Proglottids shed in feces
Cysticercus in muscle of IH
How can humans be an accidental IH for T. solium?
Self infection with eggs
Cysticerci in various locations
Neurocysticerosis
What are the adult stages of Echinococcus spp like?
Very small
What are the metacestodes of Echinococcous spp like?
Very large
What is the zoonosis of Echinoccous spp metacestodes?
They are zoonotic
What is the DH of Echinococcus granulosus?
Canids
What is the IH of Echinococcus granulosus?
Primarily ungulates
What is the life cycle of Echinococcus granulosus?
Hydatid is digested by DH –> scolices embeded in SI mucosa –> develop into adults
Taeniid eggs in feces
Unilocular hydatid cyst in liver, lung, and other organs of IH
What is the sylvatic cycle of Echinococcus granulosus?
Wolf (DH) –> caribou (IH)
Dingo (DH) –> kangaroo (IH)
What is the domestic cycle of Echinococucs granulosus?
Dogs (DH) –> sheep (IH)
What is the zoonotic risk with Echinococcus granulosus?
Humans are accidental IH
Primaruly by ingesting eggs while handling dogs
Benign neoplasia; cystic echinococcosis
Endemic areas in Australia, Africa, South America
What is the DH of Echinococcous multiocularis?
Foxes, other canids; rarely cats
What is the IH of Echinococcous multiocularis?
Rodents
What is the life cycle of Echinococcous multiocularis?
Hydatid is digested by DH –> scolices embeded in SI mucosa –> develop into adults
Taeniid eggs in feces
Multiocular hydatid cyst in abdominal cavity of IH
What is the most common cycle of Echinococcous multiocularis that we see?
Sylvatic cycle: artic fox (DH) –> vole (IH)
Is there a zoonotic risk with Echinococcous multiocularis?
Humans are rarely an accidental IH
What are other names for Diplydium caninum?
Cucumber tapeworm
Flea tapeworm
Double-pored tapeworm
What is the DH of Diplydium caninum?
Felids and canids
How is the DH infected with Diplydium caninum?
Ingestion of infected IH
What is the IH is Dipylidium caninum?
Ctenocephalides felis
Can people get Diplydium caninum?
Yes, by eating the infected flea (especially kids)
What is the life cycle of Diplydium caninum?
Egg "packets" Flea larva ingests eggs Cysticercoid in IH DH ingests flea Proglottids shed in feces
What is the PPP of Diplydium caninum?
2-3 weeks
What is the DH of Anop;pcephala perfoliata?
Equids
Where is Anoplocephala perfoliata found in equids?
Ileum, cecum, ileocecal junction
What is the IH of Anoplocephala perfoliata?
Oribatid (free-living) mites
What can Anoplocephala perfoliata cause pathology in?
DH: may be associated with certain types of colic
What is the larval stage with Anoplcephala perfoliata?
Cysticercoid
Describe Anoplocephala magna
Life cycle similar to A. perfoliata
Posterior small intestine
Larger than A. perfoliata; no lappets
Relatively harmless
Describe Paranoplocephala mamillana
Life cycle similar to A. perfoliata
Anterior small intestine
Smaller than A. perfoliata; no lappets
Relatively harmless
What is the DH of Moniezia spp?
Ruminants
What is the IH of Moniezia spp?
Oribatid mites
What is the larval stage of Moniezia spp?
Cysticercoid
Are Moniezia spp considered pathogenic?
No
What is found in the egg of Anoplocephala spp, Paranoplocephala and Moniezia spp?
Pyriform apparatus
What is Thysanosoma sp?
Fringed tapeworm
What is the DH of Thysanosoma sp?
Small ruminants; rarely cattle and deer
What is the IH of Thysanosoma sp?
Booklice or bark lice
Where are adult Thysanoma sp found?
In bile duct and duodenum
What is the larval stage of Thysanomsoma sp?
Cysticercoid
What is the DH of Spirometra spp?
Felids (bobcat)
Canids
Raccoons
What is the 1st IH for Spirometra spp?
Copepod (procercoid)
What is the 2nd IH for Spirometra spp?
Lots… non-fish vertebrates (plerocercoid)
What is the PH of Spirometra spp?
Non-fish vertebrates
Where are Spirometra spp common?
Southeastern US
What are adult Spirometra spp associated with?
GI signs in dogs and cats (vomiting, diarrhea, weight loss)
What is sparganosis?
When the plerocercoid of Spriometra spp causes disease in humans
What can humans become with Spirometra spp?
2nd IH- ingestion of copepod with procercoid
or PH- ingestion or transfer or plerocercoid
What happens if a cat ingests copepods with the procercoid?
It gets sparganosis and becomes a 2nd IH
What is the DH of Diphyllobothrium latum?
Canids, felids, humans
What is the 1st IH of Diphyllobothrium latum?
Copepods (procercoid)
What is the 2nd IH of Diphyllobothrium latum?
Small freshwater fish (plerocercoid)
What is the PH of Diphyllobothrium latum?
Large freshwater fish
Describe human infections with Diphyllobothrium latum
No or mild clinical disease
Acute: GI symptoms
Chronic: Vit B12 deficiency –> deficiency; nerve degeneration
What is the pathogenesis of adult Cyclophyllidean cestodes in the DH?
Generally do not cause disease
What is the pathogenesis of Diphyllobothriidean cestodes in the DH?
They are more likely to cause disease
What does the pathogenesis of metacestodes in IH depend on?
Location
Size
Invasiveness
What is the pathogenesis of Diphyllobothriidean metacestodes in 2nd IH?
Spirometra causes sparaganosis
What is important in controlling cestodes?
Prevention of infection and reinfection (flea control, prevent carnivory)
What are the zoonotic cestodes with humans as accidental IH?
Echinococcus granulosus
E. multiocularis
Spirometra spp (2nd IH or PH)
Taenia solium
What are the zoonotic cestodes with humans as accidental or normal DH?
Diplyidium caninum (accidental)
Taenia solium
Taenia saginata
Diphyllobothrium latum