Trematodes And Schistosomes Flashcards

1
Q

Trematodes

A
  • members of platyhelminthes
  • flat, fleshy, leaf shaped worms
  • have two muscular suckers
  • have partial alimentary tracts,

-are hermaprodites except for schistosomes.
(they have cylindric bodies and separate male and female worms exist. Shistosomes also don’t have an operculum).

  • Flukes require mollusks (snails and clams) as the first intermediate host.
  • Flukes have an an operculum.
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2
Q

Fasciolopsis buski

A

Trematode
(giant intestinal fluke)
- largest, most prevalent, and most important intestinal fluke.

  • Humans ingest vegetatin contaminated with the metacercaria (encysted larva) which develop into immature flukes in the duodenum.
  • The adult fluke attaches to the mucosa of the small intestine and undergoes self-fertilization, 3 months later eggs are passed and free swimming larva (miracidium) emerges and infects snails.
  • Pigs, dogs, and rabbits serve as reservoir hosts.
  • Inflammation, ulceration, and hemorrhage.
  • Severe infections feels like a duodenal ulcer, as well as diarrhea.
  • Stools may be profuse, a malabsorption syndrome similar to giardiasis is common, and intestinal obstruction can occur.
  • Eggs look like Large, golden, bile-stained eggs with an operculum on the top.
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3
Q

Fasciola hepatica

A

Trematode
(sheep liver fluke)
- A parasite of herbivores (particularly sheep and cattle)

  • migrate through the liver parenchyma, and enter the bile ducts to become adult worms.
  • Approximately 3 to 4 months after the initial infection, the adult flukes start producing operculated eggs.
  • Sheep to Snailss.
  • snail as an intermediate host.
  • consumption of contaminated watercress.
  • tenderness, and hepatomegaly.
  • Pain in the right upper quadrant, chills, fever.
  • in the bile ducts cause mechanical irritation and toxic secretions leading to hepatitis, hyperplasia of the epithelium, and biliary obstruction.
  • Can cause liver rot.
  • eggs indistinguishable from the eggs of F. buski.
  • Eggs in bile are diagnostic..
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4
Q

Clonorchis sinensis

A

Trematode
(Chinese liver fluke)
-two intermediate hosts.
-snail and fish

  • the eggs are eaten by the snail, where reproduction begins, fresh water fish then take up the cyst where it develop into infective metacercariae
  • flukes develop first in the duodenum and then migrate to the bile ducts, in which they become adults.
  • Can survive for 50 years.
  • Eggs pass in feces.
  • Common infections seen among Asian refugees.
  • chronic infection can result in adenocarcinoma of the bile ducts..
  • gallbladder may produce cholecystitis, cholelithiasis.
  • Liver dysfunction.
  • Repeat stool necessary.
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5
Q

Paragonimus westermani

A

Trematode
(Lung fluke)
- infective stage occurs in a second intermediate host: the muscles and gills of freshwater crabs and crayfish.

  • Humans ingest infected meat, larva ultimately ending up in the pleural cavity.
  • Eggs appear in sputum, or in feces.
  • consumption of uncooked freshwater crabs and crayfish.
  • Fever, chills, inflammatory reaction in the lungs, sputum, severe chest pain, RUSTY SPUTUM, Dyspnea, chronic bronchitis,
  • Fibrosis in the lung tissue
  • can make it to the spinal cord.
  • Sputum and feces reveals golden brown, operculated eggs.
  • radiographs often show infiltrates, cysts, and pleural effusion.
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6
Q

What is the most prevalent intestinal fluke

A

F. Buski

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7
Q

Schistosomes

A

-Cause schistosomiasis, also known as bilharziasis or snail fever.

  • Male/female.
  • No operculum,
  • Obligate intravascular parasite (not found in cavities, ducts, and other tissues)
  • Skin penetrating free-swimming cercariae (not ingested).
  • coat themselves with substances that the host recognizes as itself.
  • develop in the portal vein.
  • eggs elicit an intense inflammatory.
  • the larvae inside the eggs produce enzymes that aid in tissue destruction.
  • earliest signs and symptoms are caused by the penetration of the cercariae through the skin.
  • Immediate and delayed hypersensitivity to parasite antigens result in an intensely pruritic papular skin rash.
  • Katayama syndrome.
  • fever, chills, cough, urticaria, arthralgias, lymphadenopathy, splenomegaly, and abdominal pain.
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8
Q

S. Mansoni

A

Schistosome

  • most widespread
  • resides in the small branches of the inferior mesenteric vein near the lower colon
  • eggs of S. mansoni are oval, possess a sharp lateral spine
  • primates, marsupials, and rodents.
  • disease of economic progress;.
  • Needs a suitable snail host.
  • Itch>rash> cough>hepatitis.
  • Can be chronic or fatal.
  • Chronic: hepatosplenomegaly, ascites, white pseudotubercles on liver.
  • fatal schistosomiasis, fibrous tissue, reacting to the eggs in the liver, surrounds the portal vein in a thick, grossly visible layer (“clay pipestem fibrosis”)
  • Anthelmintic therapy does not affect lesions caused by eggs already deposited in tissue.
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9
Q

S. Japonicum

A

Schistosome
(oriental blood fluke)

  • resides in branches of the superior mesenteric vein around the small intestine and in the inferior mesenteric vessels
  • eggs are smaller, are almost spheric, and possess a tiny spine.
  • are carried to more sites in the body (liver, lungs, brain).
  • frequently involves cerebral structures. lethargy, speech impairment, visual defects, and seizures.
  • Needs a suitable snail host.
  • Found in stool.
  • At risk occupation: workers in rice paddies/ irrigation projects.
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10
Q

S. Haematobium

A

Schistosome

  • develops in the liver and migrates to the vesical, prostatic, and uterine plexuses of the venous circulation,.
  • Large eggs with a sharp terminal spine.
  • in the uterine and prostatic tissues.
  • can break free and are found in urine.
  • Reservoir hosts include monkeys, baboons, and chimpanzees.
  • Leading cause of cancer of the bladder in Egypt.
  • hematuria, dysuria, and urinary frequency.
  • Attacks bladder and lungs. dyspnea, cough, and hemoptysis.
  • large, terminally spined eggs.
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11
Q

Cercarial dermatitis

A

Schistosome
(“swimmer’s itch”).

  • cannot develop into adult worms.
  • hosts are birds and other shore-feeding animals from freshwater lakes.
  • intense pruritus and urticaria.
  • lead to secondary bacterial infection from scratching.
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