Parasites Review Lecture Notes Flashcards
What is the Taxonomy name for a Tape Worm
Cestode
What is the head of the tapeworm called
A scolex
What are the individual segments of an tape worm called
proglottids
What is a chain of proglottids called
A strobilli
Was is the sex of a cestodes
Hermaphrodites
What is the digestive system of cestodes
They dont have one
Can humans serve as the intermediate host of cestodes
Yes
When humans are the host for cestodes what happens
We get the “baby” tape worm
When humans are the Intermediate host for tapeworms ( cestodes) what happens
Cysiticercosis
Echinococcosis
Sparganosis
In cestodes, is it worse to be the initial host or the intermediate host
Intermediate host
What is the difference between Taenia solium and Cysticerosis
They are the same parasite and the same egg.
If egg is ingested: you’ll be the intermediate host. S/s cysts
If larva is ingested: you’ll grow an adult tapeworm that will release eggs.
How does someone get cysticerosis
Contact with human feces
Eating the T. Solium eggs
How is Taenia Solium ingested
By eating undercooked pork
What are the S/s of Taenia Solium
Indigestion and Diarrhea
What is the sign of someone with cysticercosis
Development of cyst following ingestion of T. Solium
How do you prevent ingestion of T. Solium
Cooking pork
How do you prevent Cystercosis
Proper Saniation
Avoiding feces
What is the name for the Cow Tape worm
Taenia Saginata
Are humans the intermediate host for Taenia saginata
No, the cow is
How is Taenia saginata ingested
By eating undercooked beef or contact with human feces
S/s of ingesting Taenia saginata Aka Cow tapeworm
Can be asymptomatic
Vagua abdominal pains
Chronic indigestion
Hunger pains
How can you prevent ingesting Taenia saginata
Cook meat properly and sanitation
What is the definitive host for Cow Tape worm
Aka Taenia saginata
Definitive host humans
What is the name for the Fish Tape worm
Diphyllobothrium Latum
What is the structure of proglottids for the fish tape worm
Aka diphyllobothrium latum
Structure: wide flat and thin
What are the two intermediate hosts for diphyllobothrium latum
The crustacean and freshwater fish
How is Diphyllobotrium latum ingested
Eating fish carrying the tapeworm
How are humans infected by Diphlyllobothrium latum
Eating raw or undercooked fish
Where is Diphyllobothrium latum most prevalent
In cool lake regions
Where raw or pickled fish is popular
What are the most common causes of Diphyllobothrium latum ingestion
Cooking fish over campfires or geflite fish
What are the s/s of diphyllobothrium latum infection
Usually asymptomatic
Occasionally Epigastric pain, abdominal cramps, N/V, and weight loss
40 percent of patients who ingest Diphyllobothrium latum present with what finding
Low b12
What is the larva form of D. Latum
Sparganosis
How is sparganosis ingested
(Larva form of D. Latum)
Drinking pond or ditch water that contains crustaceans (copepods)
Eating tadpoles, frogs, or snakes
What are the S/s of sparganosis ingestion
Painful inflammatory tissue reactions in subQ tissue
In the eye: painful, periorbital edema, corneal ulcers and ocular involvement
If there are hydatid cycst… think…
Echinococcos granulosas
Where is echinococcus most prevalent
In sheep farmers
How is Echinococcus ingested
Contaminated water or vegetation from sheep or canines
Hand to mouth transmission of canine feces
What are teh S/s of Echinococcus granulosus
Cysts!
When diagnosing Echinococcus granulosus what must you be cautious of..
Aspiration might confirm the diagonis but has a HIGH risk of anaphylaxis reaction.
If you are going to aspirate a Echinococcus granulosus cyst what should you add…
Formalin
Where does the Adult Echinococcus Granulosus reside in its definitive host?
In the bowel
Are humans the intermediate or definitive host for E. Granulosus
No
What are the hosts for Echinococcus multilocularis
Rodents, foxes, wolves, dogs, cats
What is the intermediate host for E. Multilocularis
Rodents
How are humans infected with cyst stage E. Multilocularis
Contact with foxes, dogs, or cat feces contaminated with eggs
What occupation is most associated with E. Multilocularis
Trappers
Handle fur pelts and inhale fecal dust with the eggs
What causes hydatid cycst in the liver and lungs
E. Multilocularis
What egg tapeworm mimics the appearance of carcinoma
E. Multilocularis
Because there are no protoscolices
What tapeworm causes obstruction of the biliary and portal pathways in the liver
E. Multilocularis
What tapeworm mimics hepatic cirrhosis
E. multilocularis
-malnutrition, ascites, and portal hypertension
If left untreated what is the mortality rate of E. multilocularis
70 percent
How do you prevent E. Multilocularis
Deworming farm dogs and cats
What is the size of hymenolepis nana
Dwarf tapeworm 2-4cm
Does hymenolepis nana require and intermediate host
No
Do hymenolepis nana need to leave there host at any point?
No
Eggs are able to hatch into larva, then grow into adults, without leaving the host
Can lead to hyper infection and several clinical symptoms
Other than humans what two vectors are associated with hymenolepis nana
Beetles and mice
What is the most common tape worm in N. America
Hymenolepis nana
What are the places you can ingest Hymenolepis nana from
Contaminated grain and flour
Day Care centers for children are hot spots
What are the S/s of Hymenolepis nana
Heavy infection:
Diarrhea, abdominal pain, headache, anorexia.
Because Hymenolepis nana doesn’t need to leave its host, this can cause
Auto reinfection and severe symptoms
What does H. Nana egg look like
Six hooked embryo and polar filaments
What is a tapeworm that is closely related to H. Nana and primarily found in rats and mice
Hymenolepis diminuta
What is the physical difference between H. Nana and H. Diminuta
The scolex of H. Diminuta lacks booklets, and the egg is larger and has no polar filaments and is bile stained
What does the lifecycle for Hymenolepis diminuta require
Requires insect for development
How do humans ingest Hymenolepis diminuta
Larval insects feed on infected rat feces and humans eat the larva in contaminated grains
What is the cause of H. Diminuta ingestion
Rodent contamination/ worms in uncooked grains
What are the S/ s of H. Diminuta infection
Can be asymptomatic
Or cause N/D abdominal discomfort, anorexia
What is the physical characteristics of H. Diminuta
Bile stained egg that lacks polar filaments
How do you prevent H. Diminuta
Rodent control where grain is stored
Dipylidium caninum is primarily a worm associated with what animal
Dogs and Cats
What is the life cycle for dipylidium caninum
Development off larva worms in dos and cat fleas
What do the eggs of dipylidium caninum look/ present
Free eggs are rarely seen
Egg packets that contain 8-15 six hooked on o sphere in a thin membrane are most commonly found in fecal specimens
What is the cause of Dipylidium caninum infection
Pet chews/ crushed fleas, licks a child mouth or direct swallowing infected fleas leads to intestinal infection
Who is most at risk of dipylidium caninum
Children near dogs and cats
What are the S/s of Dipylidium Caninum
Light- asymptomatic
Heavier- abdominal discomfort, anal pruritus, and diarrhea
What causes the anal pruritus associated with D. Caninum
Motile proglottids
How do you diagnose D. Caninum
Microscopic eggs in feces
Or Visible proglottids in feces
(Stool sample)
What is the name from Flukes
Trematodes
What is the shape of trematodes
Flat, fleshy, leaf shaped worms
What is the digestive system of trematodes
Aka flukes
Lateral tubes that do not join to form an excretory opening
What is the sex of most flukes and what is the exception
Hermaphroditism except for schistosomes
What do flukes require as their first intermediate host
Mollusks (snails and clams)
All flukes have an operculum except for the
Schistosomes
What is the largest, most prevalent, and most important intestinal fluke
Fasciolopsis buski
What is another name for Fasciolopsis buski
The giant intestinal fluke
How do humans ingest Fasciolopsis buski
Ingesting the metacercaria (encestes larva) on water chestnuts or water plants
Where do the metacercaria of fasciolopsis buski develop into immature flukes
In the Duodenum
Where does the adult fluke of Fasciolopsis buski attach to and what does it do there
In the mucosa of the small intestine and undergoes self fertilization
How long does it take F. Buski to go from ingestion to eggs
3 months
What is the free swimming larva of F buski called
Miracidium
What is the reservoir for F. Buski
Needs snail host
And in china, Vietnam, indonesia, maylasia, and India pigs, dogs and rabbits serve as reservoir host
What are the S/s of F. Buski infection
Inflamation, ulceration, and hemorrhage.
Feels like a duodenal ulcer,
Diarrhea Malabsorption syndrome similar to giardiasis Intestinal obstruction Marked eosinophilia (RARELY CAUSES DEATH)
What does F. buski look like
Large, golden, bile stained egg with operculum on the top
What is the name of the sheep liver fluke
Fasciola hepatica
What organ does Fasciola hepatica migrate through
Migrates through the liver parenchyma and enter the bile ducts to become adult worms
At approx 3-4 months after F. Hepatica infection what do the adult flukes start to do..
Starts producing operculated eggs that are identical to F. Buski
What are the S/s of F. Hepatica
Liver irritation, tenderness, and hepatomegaly.
Pain in the RUQ, chills, fever, and marked eosinophilia
Worms in bile ducts cause irritation and toxic secretion leading to hepatitis, hyperplasia, and biliary obstruction
Can cause LIVER ROT
Portal cirrhosis is common
How do you diagnose F. Hepatica
Eggs are indistinguishable from F. Buski
Eggs in bile is diagnostic
What is the name for the Chinese liver fluke
Clonorchis sinensis
How many intermediate host does C. Sinensis require
2 intermediate hosts
What is unique about C. Sinensis (fluke)
Differs from other flukes in that the eggs are eaten by the snail where reproduction begins
What are the two intermediate hosts for C. Sinensis
- Snail
2. Fresh water fish
After ingestion by its secondary host (fresh water fish ) C. Sinensis does what…
Fresh water dish ingest the cercaríae cyst where it develops into infect metacercariae
What is the way in which humans ingest C. Sinensis
Uncooked freshwater fish are eaten
Flukes develop in the duodenum and then migrate to the bile ducts to become adults
How long can C. Sinensis survive in the biliary tract
50 years producing 200 eggs a day
What population has common C. Sinensis
Asian refugees
What are the reservoirs and hosts for C. Sinensis
Raw, pickled, smoked, or dried freshwater fish that harbor the metacercariae
Dogs, cats, and fish eating mammals can serve as reservoirs as well
What are the S/s of C. Sinensis
Usually asymptomatic
Severe infections occur with many flukes in the biliary ducts
-Fever, diarrhea, Epi gastric pain, hepatomegaly, anorexia, jaundice
Can cause biliary obstruction
Can Cause adenocarcinoma of the biliary duct
Invasion of the gall bladder can cause cholecystitis, cholethiasis, and impaired liver function
How do you diagnose C. Sinensis
Eggs in stool
Repeat stool cultures may be necessary
In acute symptomatic infection: ther are usually eosinophilia and an elevation of serum alkaline phosphate levels.
Radiographs may detect abnomalities in biliary tract
What is the name for the Lung Fluke
Paragonimus westermani
When does the infectious stage for P. Westermani occurs
In a secondary intermediate host: the muscles and gills of freshwater crabs and crayfish
How do humans ingest P. Westermani
Ingest infected meat, larval worm hatches in the stomach and ends up eventual in the plural cavity
Where does the adult worm for P. Westermani reside
In the lungs where it produces eggs that are liberated from ruptured bronchioles and appear in the sputum or when ingested in the feces
What are the two intermediate hosts for P. Westermani
Snails
Crayfish/ Crab
What is the cause of P. Westermani ingestion
Consumption of uncooked freshwater crabs and crayfish
What are the S/s of P. Westermani ingestion/ infection
Fever, chills, high eosinophilia
In the lungs, adult flukes produce, Inflamation, with fever, cough, and increased sputum
Blood sputum with eggs (rusty sputum)
And severe chest pain
Can cause dyspnea , chronic bronchitis, bronchiectasis, and pleural effusion
As well as fibrosis in the lungs
If larva migrate to the spinal cord or brain then there may be severe neurological disease
How do you diagnose P. Westermani
Sputum and Feces reveal golden brown, operculated eggs.
Chest Radiographs show infiltrates, nodular cysts, and pleural effusions.
Where is Schistosomes a major parasitic infection
Tropical Areas
230 million infections worldwide
What do schistosomes cause
Schistosomiasis, aka bilharziasis or snail fever
Snail fever aka
Schistosomiasis
How are schistosomes different than flukes
Obligate intravascular parasites
Skin penetrating not ingested
Have no operculum
And are Male/ Female not hermaphroditism
Where do schistosomes develop in humans
In the intrahepatic portal circulation
Or in the visceral, prostatic, rectal, or uterine plexuses/ veins
What is the vector for schistosomes
Snails