SEX ANATOMY (Female) Flashcards
What happens on Day 10 of the preovulatory phase
One of the secondary follicles has outgrown all other follicles and becomes the dominate follicle
What layer do the spiral Arterioles supply blood to..
The stratum functionalis
How many mammary glands are in each breast
One
Where is the IUD inserted into
The internal Os of the uterus
Prevents sperm from entering the uterus
Which layer of the cervix contains lubricating glands
The endocervix
If not fertilized at time of uterus arrival, what happen to the oocyte
Begin to disintegrate
Menses
What are the two peritoneal pouches of formed around the uterus
The vesicouterine pouch and the retrocouterine pouch
The broad ligament is made of..
Double folds of the peritoneum
The dying of the stratum functionalis layer causes what..
The cells to slough off, Menses
Where does milk emerge from in the nipple
Lactiferous ducts
In relation to Menses, what does Inhibin do?
Secreted by granulosa cells and corpus luteum after ovulation
Inhibits secretion of FSH and LH
What is the function of the zona pellucida
Helps the corona radiata/ cumulus-granulosa cells attach to the oocyte.
What is the Ovum + the nuclei of a sperm called
A diploid zygote
What are the physical characteristics of the plateau phase of female sex response
- marked vasoconstriction
- sex flush
- engorgment of lower 1/3 of vagina
- narrowing of diameter
- dilation of upper 2/3 of vagina
What arteries supply the stratum basalis of the myometrium
The straight arterieoles of the radial arteries
What happens to the expelled oocytes if fertilization does not occur
All cells degenerate
What are the structures of the female reproductive system
Ovaries Fallopian Tubes Uterus Vagina Vulva/ Pudendum *mammary glands
What is the union of a secondary oocyte and a sperm cell called
Fertilization
A zygote
What are the 4 phases of the female reproductive cycle
Menstrual
Perovulatory
Ovulation
Postovulatory
What is the current that moves the oocyte for the peritoneal cavity to the Fallopian tube?
Currents produces by fimbriae that surround the mature follice just released from the ovary
Peristaltic movements of the tubal layers move the secondary oocyte tot he uterus
What is coopers ligaments
A ligament that run between breast and skin fascia, become looser with excess age or strain
(Jogging)
Perky breasts
Which two hormones prepare and maintain the endometrium
Estrogen and progesterone
What is the normal position for the uterus
Ante flexion
Body of the uterus protects anteriorly over the bladder
What is the transformation zone of the cervix
The space between the original and the new squamocolumonar junction
What is it called when the uterus is facing the opposite of normal
Retro flexion
How much blood is lost in the menstrual phase
50-150 ml of blood, tissue, mucus, and epithelial cells shed from the endometrium
Approx how many follicles with a female have a puberty
~300,000
What are the two layers of the theca folliculi of the secondary follicle
Theca Interna
(High vascularized cells, secretes precursor androgen that gets converted to estrogen)
Theca externa (Outer later of stromal cells and collagen fibers)
GnRH promotes increased release of…
FSH and LH
Milk ejection is stimulated by
Oxytocin
In relation to menses what does FSH do
Initiates follicular growth
The androgens made by LH are taken up by granulosa cells and turned into estrogen under the influence of FSH
What is the corpus luteum
aka yellow body
Contains remnant of mature follicle after ovulation
What days does the postovulartory phases of the reproductive cycle
15-28
Declining levels of progesterone and estrogen caused the reales of…
Prostaglandins
Which haploid (small/larger) is released for ovulation
The secondary (larger) oocyte
What is an irreversible procedure as as an alternative to tubal ligation
Enssure
Coil is inserted into the tubes which causes scar tissue to form
What structures does the broad ligament support
The ovaries, Fallopian tubes and the uterus
What phase is also known as the secretory phase
The post ovulatory phase
What S/s of Benign prostatic hyperplasia
Frequent urination
Bed wetting
Decreased force of stream
Postvoiding dribbling
What is the source of mental flow
Uterus if implantation does not occur
Which haploid cell undergoes meiosis II
The larger haploid cell ( secondary oocyte)
What two cells breaking down become the corpus luteum
The basement membranes between the theca interna and the granulosa cells mix under the presence of LH and become the corpus luteum
What is the fornix of the vagina
Recess area that surround the vaginal attachment to the cervix
what phase is also known as the proliferative phase
The preovulatory phase
What are the two parts of the broad ligament
The mesometrium part
The mesovarian part
Why is the postovulatory phase known as the secretory phase
Because of the secretion of glycogen by the secretory glands of the endometrium
How many primordial follicles are lost per month.. .due to what?
5,000 -15,000
Atresia (degeneration) or Apoptosis
What is the preovulatory phase
Lasts from day 6-13 of reproductive cycle
What is the pudendum
The vulva
Refers to the external genitalia of the female
How does progestin work in oral contraceptives
It’s a hormone with actions similar to progesterone
- thicken Cervical mucous to block sperm
- also block implantation in the uterus
When does cell division of the zygote begins
While moving towards the uterus
Posteriorly the perimetrium covers what and forms what pouch ?
Covers the rectum
And forms the retrocouterine pouch
What ligaments are inferior to the base of the broad ligaments and extend from the pelvic wall to the crevix and vagina
Cardinal (lateral) ligaments
When is the zona pellucida and the cumulus granulosa attaching ?
Begins in primary follicle development and completes as secondary follicles
Estrogen is synergistic with what other hormones
HGH
What is the tx for Bartholin Gland Cysts
I&D, placement of a word catheter ballot for days-weeks to allowing for healing of duct
What hormones are produced by the female gonads
Progesterone
Estrogen
Inhibin
Relaxin
Where does the sperm cell usually encounter the secondary oocyte
In the Fallopian tubes
Fertilization
What are the cells that surround a follicle called…
What do they do..
Granulosa cells
Begin with cells in single layer awaiting oogenesis (primordial follicle)
Under the influence of FSH cells multiply into layers
(Primary/ secondary follicles)
How many primordial follicles with become mature and ovulated in a females lifetime
~400
What area of the cervix is vulnerable to the HPV virus
The transformation zone
-area for cervical cancers
What is the thickness of the endometrium in the postovulatory phase
12-18 mm
What ligament connects the cervix to the sacrum
The uteroesacral ligament
What changes oogonia into primary oocytes
At 20 weeks gestation
Oogonia are stimulated to begin meiosis 1 which changes tier classification to primary oocytes
In relation to the menses what does GnRH do
Controls both the ovarian and uterine cycles
Stimulates the release of LH and FSH
Stimulates ovarian follicles to produce estrogen
At what week of fetal development is “mid-gestation peroid” of oogensis
20 weeks
Describe the perineum in both men and women
Diamond shaped area medial to thigh and buttocks
Contains the external genitalia and anus
What is the role of granulosa cells in the secondary follicle
Continues to secrete estrogen Luis that builds up in a cavity called the antrum
High estrogen causes what to be released from the Hypothalmus and what from the ant. Pituitary
Hypothalamus: GnRH
Ant. Pituitary: LH
What is the most distal portion of the glans clitoris
The corpus cavernosum of the clitoris
What is the central portion of the uterus called
The body of the uterus
What are the physical characteristics of the resolution phase
Return to pre-excitement phase
The estrogen and the Inhibin secreted by the dominant follicles decrease the release of…
FSH which causes the other less developed follicles to stop growing and undergo atrisia
What is the corpus cavernosum of the clitoris
Erectile and very sensitive tissue that fills with blood during sexual arousal
Engorges the glans clitoris
What is the exposed portion of the clitoris called.?
The glans clitoris
What are the two phases that make up the follicular phase of the reproductive cycle
Menstrual and preovulatory phases
If the oocyte is not fertilized the corpus luteum becomes the…
Corpus albicans
What covers the surface of the ovaries
The germinal epithelium
What are the sections of the Fallopian tube
From the cervix to the body of the uterus Entrance is the intramural To the isthmus To the ampulla To the infundibullum Ends in the ovary
At what age does the prostate double in size
What is this called
Around age 60.
Benign Prostatic Hyerplasia
BPH
What hormone stimulates the ovarian follicles to produce estrogen
GnRH
What arteries supply the stratum functionalis
The spiral Arterioles of the radial arteries
What is the difference between the ovarian cycle and the uterine cycle
Ovarian: includes changes that occur during and afternoon maturation of the locate
Uterine: involves changes in the endometrium that prepare it for implantation of the developing embryo,
Once sperm penetrates the zona pellucida, it signals the secondary oocyte to do what…
To complete meiosis II
Producing an ovum and a secondary body.
What is the inferior extension of the uterus into the vaginal canal called
The cervix
What are Bartholins glands
Greater Vestibular Glands
Lateral to the vaginal orifice
Produce mucous during sexual arousal to provide lubrication
Describe the uterosacral ligaments
Lie on either side of the rectum,
Connect the uterus to the sacrum
Approx how many oogonia will a female have a mid gestation
~7 million
What causes ovulation
High levels of estrogen in the preovulatory phase exert a postive feedback for LH and GnRH and cause ovulation
In the post ovulatory phase, LH stimulates the corpus luteum to secrete.
Progesterone
Estrogen
Inhibin
Relaxin
What are the risks of birth control
May not be advised for women with history of:
- blood clots
- cerebral blood vessel damage
- migraine headaches
- hypertension
- liver malfunction
- heart disease
- SMOKING= NO
What causes hot flashed as heavy sweating
GnRH
What is the order of ligaments of the uterus from superior to inferior
Round
Cardinal
Uterosacral
(Broad covers all three)
What is a Grafiaan follicle
aka vesicular follicle
Large, fluid filled follicle that is ready to rupture
-expels the secondary oocyte (ovulation)
What are the borders of the perineum
Anterior portion is the pubic symphysis
Lateral portions are the ischial tuberosities
Coccyx is the posterior portion
High levels of progesterone inhibit…
GnRH
When the granulosa cells thicken around the primary follicle, what do they secrete
Estrogen, that starts to file the inside of the follicle
What hormone secretion increases as the size of the dominant follicle increases
Estrogen
What happens to bone density as estrogen decreases
Mineral density of bones decreases
Where does blood leaving the uterus drain into
Uterine veins, draining into the internal iliac veins
What part of the uterus wall is part of the visceral peritoneum
The perimetrium
When fragile columnar cells get exposed to the acidic vaginal environment what happens
Metaplasia occurs, forming a new squamocolomanr junction
What does teh corpus luteum degenerate into
Scar tissue called the corpus albicans
After ovulation, what happens to the Graafian follicle
It collapses
Basements membrane between the theca interna and granulosa cells break down, becomes the corpus luteum
In relation to Menses, what does estrogen do
Promotes development and maintenance of: Reproductive structures Breasts 2* sex characteristics Voice pitch Weight distribution Broad Pelvis Pattern of hair growth Increases protein anabolism Lowers blood cholesterol Moderate levels of estrogen inhibit release of GnRH and FSH/LH
When the sperm penetrates the cytoplasm of the ovum, what happens?
This causes tow pronuclie to from and fuse, restoring the diploide chromosome number and forms the ZYGOTE
When do the predatory changes of the post ovulatory phase peak..
1 week after ovulation
To prepare the arrival of the zygote or secondary oocyte
What are the two cell types of the cervix
Ectocervix- stratified squamous epithelium
Endocervix- tall columnar epithelium
At what point will a female have generated all the primordial follicles she will ever have
At mid gestation
What is the larger haploid cell called
Secondary oocyte.
During the preovulatory phase, what happens to the endometrium
Estrogen stimulates the repair of the endometrium , thickening it in size to about 4-10 mm.
Cells of the stratum básalis undergo mitosis and produce the stratum functionalis
What does the corona radiata do
Convert into cumulus-granulosa cells that attach tot he oocyte
Secrete progesterone, thought to attract spree to the oocyte
Primordial follicles become what after stimulation of FSH/ LH
Primary Follicles
What layer of the uterus is shed each month during menstration
The stratum functional is later of the endometrium
How many chromosomes are in Oogonia ?
2n (46 chromosomes)
Under the influence of FSH, granulosa cells….
Multiply into layers, forming primary and secondary follicles
What all does the vulva include
The Mons pubis
Labia Majora and Minora
What is the squamocolumnar junction
Where the stratified squamous and columnar epithelium of the cervix meet
What are the skenes glands
Paraurethral Glands
Lateral to the urethral orifice
Secrete mucous
Embedded in the wall of the urethra
In relation to menses, what does relaxin do. ?
Produced by the corpus luteum each month
Relaxes the uterus by inhibiting contractions
Helps increase flexibility of pubic symphysis and help dilate cervix during labor
In the role of menses, what does progesterone do’?
Secreted mainly by the cells of the corpus luteum And a small portion by the corona radiata
(surrounds the ovulated oocyte)
Just before ovulation of the mature follicle, the diploid primary oocyte completes…
Meiosis I, producing two haploid cells of UNEQUAL size
Each has 23 chromosomes
What events happen in the preovulatory phase
The primary follicles have matures in to secondary follicles and start to secrete Inhibin and estrogen
What is the theca folliculi of the primary follicle
Stromal cells surrounding the basement membrane
What starts the progression of primordial follicles into primary follicles
Increased FSH
Anteriorly the perimetrium covers what structure and forms what pouch?
The bladder
And formes the vesicouterine pouch
What is the name for the anatomical top of the uterus
The fungus
What happens to primary oocytes in meisosis I
Become “arrested” until puberty
What is the white capsule of dense irregular CT deep to the germinal layer of the ovaries
The tunica albuginea
What size will the dominant follicle grow to before ovulation
Becomes the mature (Graafian) follicle
Develops to 20mm before ovulation
What days is the ovulation phase of the reproductive cycle
Occurs on days 14 or 15
Describe bartholin gland cysts
Infection, inflammation, or irritation of one or both bartholin glands
Can be painful or painless
What is the inferior most location in the female abdominal cavity
Rectocouterine pouch
-fluid tends to collect here
What are the four phases of the female sexual response
Excitement phase
Plateau Phase
Orgasm Phase
Resolution phase
Which arteries supply blood to the myometrium
The arcuate arteries and the radial (deep) arteries
Where does the development of teh fetus during pregnancy and labor occur
The uterus
What does nulliparous mean
Never had a fetus pass through the cervix
COULD STILL HAVE C- Section
How long does it take the zygote to travel and implant into the uterine wall?
6-7 days after ovulation
What structures does the broad ligament of the uterus support
The ovaries, Fallopian tubes, and uterus
What defines at primordial follicle
An arrested (meiosis I) oocyte surrounded by granulosa cells
What are the physical signs of the female excitement phase of sex
- increased desire
- deep breathing
- increased HR
- increased BP
- skin flush
- vaginal engorgment or labia and clitoris
- vagina sweating (transudative lubrication)
- secretions from bartholin glands
What fluid makes up female ejaculate
Some urine, prostate antigen from skenes glands
Some bartholin secretion
How is a vasectomy performed
Portion of each ductus defernes in removed
Tired, sutures, and the middle cut out
When does oogenesis occur
In females before birth
What are the structures that are the vestibule of the vagina
The hymen
Vagando orifice
External urethral orifice
What are the three layers of the Uterine wall
Perimetrium
Myometrium
Endometrium
What are the 4 ligaments of the uterus
Broad Ligament
Utosacral Ligament
Cardinal Ligament
Round Ligament
What are the benefits of birth control
Regulation of length of menestral cycle
Decreased mental flow
Provided protection against endometrial and ovarian cancers
Reduces risk of endometriosis
What comprised the myometrium
3 layers of smooth muscle
What are the arteries of the uterus
Uterine Arteries (branches of the internal iliac artery) Arcuate arteries (branches from the uterine arteries) Radial Arteries (branches of the arcuate arteries)
At what age do men begin to decrease testosterone synthesis
Age 50-55
Leads to reduced muscle strength, fewer viable sperm, and reduced libido.
What is the reason women under 50 have a lower risk of coronary heart disease
The cholesterol lowering effect of estrogen
Rupture of the mature (graafian) follicle and the release of the secondary oocyte into the pelvic cavity usually occurs on day….
14 of a 28 day cycle.
What is a nabothian cyst
A benign mucous cyst of the transformation zone of the cervix
-as columnar cells are transitioning to the mulitlayer, come cells are trapped still secreting mucus
In relation to Menses what does LH do
Stimulates development of ovarian follicles
Stimulates theca cells to produce androgens
LH triggers ovulation (mid cycle) Forms the corpus luteum Which then secretes -estrogen -progesterone -Relaxin -Inhibin
What is the innermost layer of granulosa cells
The corona radiata
When the oocyte is not fertilized, what hormones decrease..
what hormones increase …
Decrease: progesterone, estrogen, Inhibin
Increase: GnRH, FSH, LH
Negative feedback
Where are the alveoli of the mammary glands located
Found within the lobules of the lobes
Secrete milk
What hormone is thought to “quiet” the uterus to make it a better environment for implantation
Relaxin
What is the menstrual phase of the reproductive cycle
Lasts roughly first 5 days of the cycle
What is the prepuce
Layer of skin formed at the point wher the labia minor unite, covers the body of the clitoris
(Clitoral Hood)
At what week of fetal development for primordial germ cells migrate from the yolk sac to the gonadal ridge in females?
4th week of fetal development
What two phases make up the luteal phase of the female reproductive cycle
Ovulation and postovulatory phases
Describe the ovarian cortex
Deep to the tunica albuginea, consists of ovarian follicles surrounded by stromal cells
What is the definition of abortion
Premature expulsion of conception products from the uterus
(Usually before 20th week of pregnancy)
Can be spontaneous or induced
What are the bulbs of the vestibule
Two masses of erectile tissue that engorge during sexual arousal to narrow the vaginal orifice applying pressure during intercourse
What does parous mean
Has had a child pass through the cervix
How many lobes are in each mammary gland
Each gland contains 15-20 lobes
Where is the antrum in a secondary follice, what does it contain
In the center of the secondary follicle
Contains estrogen fluid from the granulosa cells
What does the medication mifepristone do
Induces abortion
What is the smaller haploid cell called
The first polar body,
Usually degenerates
What layer of the endometrium is permanent through mensuration
The stratum básalis
What are primordial germ cells called when the are at the gonadal ridge?
Oogonia (immature germ cells)
In the uterine cycle if implantation does not occur, what happens
The ovarian hormones recede and cause sloughing of the stratum functionalis
(Menses)
Prostroglandins causes constriction of what Arterioles
The spiral Arterioles
What is the process of oogenesis
Mitosis to meiosis producing germ cells that undergo maturation
How is tubal ligation performed
Uterine tubes are tied cute, cauterized, or clamped to prevent secondary oocyte from passing through the tubes or from sperm getting to the oocyte.
What causes the corpus luteum to persist past its 2 week life span in successful fertilization
Human chorionic gonadatropic
HCG
Approx how many primordial follicles will a female be born with at birth
~1 million
When is the onset of menopause for women
Between 40-50 years
What are the two cycles of the female reproductive cycle
Ovarian cycle and Uterine cycle
A home test kit for ovulation detects what..
The Surge of LH in the ovulation phase
What is the site of implantation for a fertilized ovum
The uterus
What happens to the oocyte if sperm is present AND penetrates
Meiosis II resumes,
Secondary oocyte splits into two haploid cells. And OVUM and a second polar body.
What are the 3 ligaments that hold the ovaries in place
The Broad ligament
The ovarian ligament
And the suspensory ligament
Why do the areola appear rough?
Modified sebaceous glands
What part of the nervous system contributes to the organs and resolution phases of the female sex response
The sympathetic
What is the life span of the corpus luteum if the oocyte is not fertilized
2 weeks
What are the two canals of the cervix
The internal and external os
Internal- from cervix to uterus
External-from cervix to vagina
How does estrogen and progestin in combination in birth control work
Combined forms inhibit ovulation by suppressing the FSH/LH
Low levels of FFSH/LH prevent development of dominate follicle in ovary
LH causes…
The mature follicle to rupture and expulsion of the secondary oocyte during the deal of the LH surge
What are the layers of the vagina
External to internal
Adventitia- anchors vagina
Muscularis- composed of outer circular layer and inner longitudinal muscle
(SMOOTH)
Mucosa- continuous with that of the uterus
Laterally the perimetrium becomes the..
Broad ligament
What is the gel-like matrix that coats the oocyte
Zona pellucida
What is the gamete function of the female gonads
Produce secondary oocytes that develop into mature ova after fertilization
What hormones does the corpus luteum produce
Progesterone
Estrogens
Relaxin
And inhibin
(Until it degenerates)
Which hormones triggers ovulation mid cycle
LH
What is the chromosome number of a zygote
2n
46 chromosomes
How long does a female reproductive cycle take
24-36 days
28*
What part of the female reproductive system is consider both part of reproductive system and the integumentary system
The mammary glands
Describe the ovarian medulla
Consists of loosely arranged CT, contains blood vessels, lymph vessels and nerves
What are the physical characteristics of the orgasm phase
Release of tension
Rhythmic myotonic contractions
Contractions of peri-vaginal muscles and anal sphincter
Uterine contractions
Milk protection is stimulated by
Prolactin
Primary follicles become…
Secondary follicles
How many primordial follicles are stimulated by FSH/LH during development cycle
10-30 stimulated by FSH/LH
What structures does the suspensory ligament support
Attached the ovaries to the pelvic wall
What are stromal cells
Fibroblast like cells in the ovarian cortex
What part of the nervous system is responsible for the female excitement phase of sex and the plateau phase of sex
The parasympathetic
Regardless of how much FSH/LH is released from the ant. Pituitary, with age what happens to estrogen
Decreases with age, regardless of FSH/LH secretion
What are the round ligaments of the uterus
Fibrous connective tissue between the broad ligaments
What are the two divisions of the perineum diamond
The urogenital triangle
and the Anal Triangle
Separated by a transverse line drawn from on tuberosity to the other
What is the region between the body and the cervix called
The isthmus of the uterus
Note the diffencene between the isthmus of the uterus and the isthmus of the Fallopian tube
Describe ovarian follicles
Lie in the ovarian cortex, consist of oocytes in various stages of development plus the cells surrounding them
What structures does the ovarian ligament support
Anchors the ovaries to the uterus