Biochem Block 2 Flashcards
Glycosidic bond in Maltose
Alpha 1-4
PGF
Hydroxyl @ 9 carbon of a prostaglandin
Polar Neutral Amino Acids
Have -OH, -SH, or Amides
Menaquinone
K
Linkage Enzyme Reaction
1 RXN for a specific bond type
Ezymes are what kind of protein
Globular proteins with 3- dimensional shape
Folic Acid
B9
Active enzymes end in…
- sins
- ase
Group Enzyme RXN
1 RXN for a type of substrates
Cholecalciferol
D
Thiamine
B1
The active site can from what kind of bonds
H-
Salt bridges
And hydrophobic RXNs
Asorbic Acid
C
2 composition of Lipids
Fatty Acids
Steroids
Polar Basic Groups
Contain NH3+ groups
Ammonium
Saturated fatty acids contain
C-C
Single carbon bonds
Non polar amino acids
Have -H, alkyl groups, or aromatic groups
BIOTIN
H/B7
Amylopectin glycosidic bonds
Alpha 1-4 and Alpha 1-6
After hydrolization form Dextrins, after hydrolization from Maltose to Glucose
3 things that affect enzyme action
Temp
PH
Concentration
Significant info on Cellulose
Cannot be digested by human body
Beta 1-4 bonds
Monounsaturated Fatty Acids Contain
Only one C=C
Aldose
A sugar with a aldehyde as its terminal group
Vmax is the
maximum rate achieved by the system
Most common form of glucose
D- glucose
AKA dextrose
Building block of cellulose and glycogen
Waxes have what functional group
esters
Arachiodonic Acid convert to make…
Prostaglandins
Aka eicasonoids
Carbon Naming for 4, 5, and 6 carbon sugars
4- tetrose
5- pentose
6-hexose
3 carbon sugar is a….
TRIOSE
Saponification
Soap
Unsaturated fatty acids contain
C=C
Carbon Double bonds
Hydrolysis RXNs
Strong acids break apart triacylgycerols
Niacin
B3
L- versus D-
L- has a -OH group on the left side furthers from the functional group
D- has a -OH on the right side furthest from the functional group
If an inhibitor covalentes bonds then the inhibition is…
Irreversible
I.e nerve agents, cyanide
Glycosidic Bond in Sucrose
Alpha, Beta 1-2
Cannot form an open chain or be oxidized
Amylose Glycosidic Bonds
Alpha 1–4
Form Helixes
3 essential Fatty acids
Linoleic Acid
Linolenic Acid
Arachodonic Acid
How do enzymes effect RXNs
Increase the rate of RXN
Are unchanged in the RXN
And Decrease the Ae of the RXN
Medical Significance of Lecithin and Cephalin
Gylcerophospholipds found in the Brian
Have polar and non polar heads
Pyridamines end is
-idine
Purines end in…
-osine
Triaclyglycerols are made up of…
A glycerol back bone and 3 fatty acids
What glycosidic bonds compose polysaccharides
Beta 1-4
Polymers of D-Glucose
Steroids molecular structure
3-6 carbon rings and 1- five carbon Ring with groups at the 18 and 19th carbon
Glycogen is also know as…
Animal Starch
(Similar to amylopectin)
Alpha 1-4 and alpha 1-6 bonds
Km is
1/2 Vmax
2 kinds of Phospholipids
Gylcerophopholipds and Sphingomylein
Pentothenic Acid
B5
Starches are digested by,…
Enzymes
Amylase: Saliva
Amylopectin/ Maltase: intestines
Comprise 50 percent of calories
PGE
Ketone @ 9 carbon in a prostaglandin
Allosteric Enzymes
Bind at the allosteric not the active site of an enzyme,
Can change the shape of the enzyme or
Can turn of the active site of the enzyme
Can block the Activtion Site
Can be a positive or negative Regulator
Fat Soluble Vitamins
ADEK
Amylose and Amlyopectin are…
Starches
Ketoses
A sugar with a ketone in is carbon chain
Poly unsaturated fatty acids contain
Multiple C=C
Most abundant steroid in the human body
Cholesterol
Antimetabolites are
Competitive Inhibitor Enzymes used in medicine
Fructose
A 6 carbon sugar with a ketone group
9 Essential Amino Acids
Histidine Isoluecine Luecine Methanione Phynelalanine Threonine Tryptophan Valine Lysine
Non competitive Inhibition effect on Km/Vmax
Km unchanged, Vmax decreases
What is Chirality
A molecule that can not be superimposed on itself
I,.e a chiral carbon bound to 4 different groups
Almost ALL naturally occurring fatty acids contain one or more….
Cis double bonds
Proteins are Denatured at what temp
50 degrees Celsius
Inactive Enzymes end in….
-ogins
Importance of D- Galactose
Cellular membranes and Nervous System
Glycosidic Bond in Lactose
Beta 1-4
Glycerophospholipids contain
two fatty acids that form ester bonds with the first and second hydroxyl groups of glycerol.
Made of amino alcohols
Pyradoxine
B6
3 kinds of Amino Alcohols
Choline, Sereing, Ethanoline
Sphingomyelin
contains sphingosine instead of glycerol.
A fatty acid, phosphate, and an amino alcohol.
Enzyme bonding can be two types
Lock and Key
Induced Fit
Sphingolipds are made of….
A sphingosine, a fatty acid, and a phosphate-amino alcohol
Fructose aka
Ketohexose
Made from the hydrolysis of sucrose
Absolute Enzyme RXN
1 RXN for only 1 Substrate
Aldopentose
A 5 carbon sugar with an aldehyde terminal group
Competitive Inhibition actions of Km/Vmax
Km increases V max unchanged
Peptide bonds are what type of bond
Amide
Glucose+ Glucose
Maltose + H20
Cholesterol is needed for…
Lipid bi-layer
Nerve tissue
Brian tissue
Vitamin D
Retinol
A
Glucose + Galactose
Lactose + H20
Cobalamin
B12
Stereoisomers
Molecules with the same empirical formula, but different molecular formulas
Covalent Modification
Enzyme activity is modified by covalent bonds to a group on the polypeptide chain that are formed or broken.
3 types of RXN types
Absolute
Group
Linkage
Tocopherol
E
Glucose+ Fructose
Sucrose + H20
Polar Acid A.A.
Have -COO- groups
Hydrogenation RXNs
Unsaturated fatty acids react with H+ and become Saturated Fatty Acids
RIBOFLAVIN
B2