Treatment Options: Radiation Therapy Flashcards

1
Q

for EBRT radiation is delivered from a ____inside/outside_____ source

A

outside

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2
Q

LINACs deliver ___ MV or higher

A

1 MV

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3
Q

cobalt-60, protons, orthovoltage are all types of ____ radiation

A

external
other types of EBRT –> photons/xrays, electrons, protons, gamma rays

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4
Q

overall radiation kills or damages _____ of cancer/tumor cells

A

DNA

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5
Q

overall radiation kills or damages DNA of cancer/tumor cells, which does what?

A

slows or stops their growth and ultimately stops the cell(s) from dividing

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6
Q

T/F: radiation therapy has BETTER cosmetic outcomes than other modalities, like surgery

A

TRUE

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7
Q

T/F: radiation therapy preserves the organ better than other modalities, like surgery

A

TRUE

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8
Q

define Therapeutic Ratio

A

it is the ratio between normal tissue tolerance over tumor lethal dose

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9
Q

Brachytherapy = ___short/long___ distance therapy

A

short

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10
Q

what is the modality called when the source is placed in or near tumor

A

brachytherapy

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11
Q

Brachytherapy can be in form of _____, _____, _____, or ____ to insert into patient

A

wires, seeds, molds, or rods

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12
Q

________ sustains surrounding normal healthy tissue because low energies are used w/ their rapid fall off

A

brachytherapy

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13
Q

T/F: Brachytherapy can be used with EBRT to provide better control

A

TRUE

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14
Q

if Brachytherapy is used with EBRT, what is considered the boost?

A

Brachytherapy

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15
Q

_____ = a way to deliver a higher dose of radiation to a more concentrated area

A

boost

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16
Q

the following are examples of _______:
– Cesium 137
– Iridium 192
– Palladium 103
– Iodine 125

A

brachytherapy

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17
Q

the following are methods of ______ application:
– external applicators
– intracavitary
– interstitial implants

A

brachytherapy

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18
Q

T/F: patients receiving brachy must be in a fully shielded room, w/ similar requirements as a trt room would have, including door interlocks, emergency buttons, and audio visual monitors

A

TRUE

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19
Q

for HDR or LDR, the patient is treated as an outpatient and can go home once the source is removed

A

HDR

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20
Q

for LDR or HDR, the source stays in the patient for longer periods

A

LDR

21
Q

for LDR or HDR, the source stays in patient for shorter periods of time

A

HDR

22
Q

for LDR or HDR, source stays in patient for 1-6 days (24-144 hrs)

A

LDR

23
Q

for LDR or HDR, source stays in patient for 10-20 minutes TOTAL and removed immediately after

A

HDR

24
Q

for __LDR/HDR__ the patient remains in hospital w/ proper shielding

A

LDR

25
Q

for __LDR/HDR__ it is delivered in fractionated schedules and can vary from twice a day for several days, to, once a week for several weeks

A

HDR

26
Q

with what implants do the sources remain in patient for life?

A

permanent implants

27
Q

T/F: the strength of permanent implants lessens daily

A

TRUE

28
Q

T/F: eventually it will be safe for permanent implant patients to be around people, however they should limit their time around kids and pregnant people

A

TRUE

29
Q

what allows for remote handling of radioactive sources, reduces dose to personnel, used for LDR and HDR treatments

A

a Remote Afterloader

30
Q

describe the sequence of events for using a Brachytherapy Afterloader -

A
  1. applicators w/o any radioactive sources are placed w/i patient
  2. position of applicators are tested w/ CT imaging everyday prior to treatment using dummy seeds or wires
  3. once position is confirmed, patient is then connected to the afterloader
  4. once safe, and all personnel has left the room the radioactive source will come out of the afterloader using a remote system and will enter into patient through seeds or wires
31
Q

T/F: the afterloader itself is shielded

A

TRUE

32
Q

the ___ is used in cases of HDR emergencies, if the source gets stuck in the patient

A

pig

33
Q

most common source used with Afterloaders is what?

A

Ir-192 (Iridium-192)

34
Q

helpful hint - you’ll know it’s a brachytherapy when the isodose lines are __around/far away___ from source

A

around
- close to source.. since brachytherapy is very short distance therapy

35
Q

the following is describing Curative, Palliative, Prophylactic, or Emergency Radiation Therapy –
*controls symptoms associated with cancer; typically delivered at 300 cGy x 10 fx

A

palliative

36
Q

the following is describing Curative, Palliative, Prophylactic, or Emergency Radiation Therapy –
*prevents spread of cancer for known patterns/high risk

A

prophylactic

37
Q

the following is describing Curative, Palliative, Prophylactic, or Emergency Radiation Therapy –
*shrinks tumor to reduce pain, bleeding, obstruction, or compression

A

emergency

38
Q

the following is describing Curative, Palliative, Prophylactic, or Emergency Radiation Therapy –
*tumor can be destroyed w/o harming healthy tissue

A

curative

39
Q

what is our perfect scenario for radiation therapy?
“___radioresistant/radiosensitive___ tumor surrounded by ___radioresistant/radiosensitive___ tissue”

A

Radiosensitive tumor surrounded by Radioresistant tissues

40
Q

what cancer typically spreads/metastasizes to the brain? And how do we treat it?

A

small cell lung cancer - PCI radiation to the brain to prevent or delay spread

41
Q

what does PCI stand for?

A

Prophylactic Brain Irradiation

42
Q

SVC stands for what?

A

Superior Vena Cava

43
Q

the following are examples of Curative, Palliative, Prophylactic, or Emergency Radiation Therapy?
-SVC, emergent GYN, spinal cord compressions

A

emergency radiation therapy

44
Q

the following describes what type of treatment - Definitive, Concurrent, Sequential, Neo-Adjuvant, Adjuvant, or Salvage
*2 trt modalities occur at SAME time; ex. chemo & RT

A

concurrent

45
Q

the following describes what type of treatment - Definitive, Concurrent, Sequential, Neo-Adjuvant, Adjuvant, or Salvage
*1 trt modality follows another

A

sequential

46
Q

the following describes what type of treatment - Definitive, Concurrent, Sequential, Neo-Adjuvant, Adjuvant, or Salvage
*radiation is primary trt modality

A

definitive

47
Q

the following describes what type of treatment - Definitive, Concurrent, Sequential, Neo-Adjuvant, Adjuvant, or Salvage
*radiation is delivered BEFORE another modality like surgery, typically to shrink tumor

A

neo-adjuvant
(neo = 1st in matrix)

48
Q

the following describes what type of treatment - Definitive, Concurrent, Sequential, Neo-Adjuvant, Adjuvant, or Salvage
*radiation delivered AFTER primary treatment modality; to treat microscopic diseases

A

adjuvant
(add in RT)

49
Q

the following describes what type of treatment - Definitive, Concurrent, Sequential, Neo-Adjuvant, Adjuvant, or Salvage
*radiation is delivered after primary treatment techniques have failed

A

salvage
(salvage what you can)