Multiple Myeloma Flashcards
Multiple Myeloma starts where?
plasma cells
plasma cells are typically found where?
in bone marrow
___ cells change and mature into plasma cells
B cells!!
multiple myeloma is the cancerous overgrowth of ____ cells
B; cause B cells mature into plasma cells
when there is an infection, ____ cells mature and change into ___ cells. As the ___ cells help fight the infection
B cells, mature into plasma cells when there is an infection
how do plasma cells help fight infection?
they make antibodies or immunoglobulins
when plasma cells grow out of control and become cancerous, this is called _________
multiple myeloma
when plasma cells are abnormal and growing out of control they make what?
M protein/M spike/monoclonal proteins/para-proteins, monoclonal and or immunoglobulins
what are certain characteristics of Multiple Myeloma? (3 main)
low blood counts, weak bones, and infections
an abundance of ____ make weak bones
osteoclasts
not enough _____ lead to infections
antibodies
anemia, thrombocytopenia, and leukopenia are all forms of ___high/low___ blood counts
LOW
____ cells make osteoclasts, which break down bones faster than osteoblast can replace it
myeloma
T/F: abnormal plasma cells don’t actually protect the body from infections, instead they crowd the area where antibodies are made… so there is a reduced supply
true
when is Multiple Myeloma diagnosed? ie. when do we know it is Multiple Myeloma?
when there is 10% or more of plasma cells are in the bone marrow
