Leukemia Flashcards
Leukemia is the cancer in/of _____________
blood forming tissues and cells; ie. stem cells
T/F: leukemia is cancer of stem cells
true
leukemia often occurs in what blood cell?
white blood cell - but can still occur in other blood cells like red or platelets
WBCs are considered ___ cells
stem
blood cells become ___ or ____
lymphocytes or myeloid cells
what staging system does Leukemia use?
FAB –> FABulous song from Phineas and Ferb and guy has WHITE HAIR like WBCs
lymphocytes are a type of _____ blood cell. And include __ or __ lymphocytes
white blood cell; and include B or T lymphocytes
myeloid cells can develop into what?
RBCs, granulocytes, or other WBCs (that are not lymphocytes)
how is Leukemia named? –> based on _____
based on which bone marrow cells the cancer starts in; so either lymphocytes or myeloid cells!
what is difference between “lymphocytic leukemias” and “lymphomas”
lymphomas start in lymph nodes and lymph tissues - and lymphocytic leukemias start in the bone marrow and blood
what does FAB stand for?
French American and British
label A, B, and C
-either Lymphoid, White, Myeloid
A = Myeloid stem cell
B = Lymphoid stem cell
C = White blood cell
how many types of Leukemia are there?
4
name the 4 types of Leukemia -
ALL (acute lymphocytic leukemia), AML (acute myeloid leukemia), CLL (chronic lymphocytic leukemia), CML (chronic myeloid leukemia)
leukemias are classified by their rate of _______ - so going into either _____ or _____
progression; acute or chronic
Acute or Chronic Leukemia is being described - fast growing and progress quickly
ACUTE
Acute or Chronic Leukemia is being described - slow growing and progress slowly
CHRONIC
which leukemia, chronic or acute, is harder to cure typically
chronic - … concept check: we want rapidly dividing, which could be acute
in which leukemia, chronic or acute, do cells mature partially but not fully
chronic - look normal but don’t act normal
which leukemia is MOST common in children?
ALL
of the four, which leukemia is most common? and most common in adults?
AML
Acute Lymphocytic Leukemia can also be called what?
Acute Lymphoblastic Leukemia
which leukemia is associated with Auer Rods?
AML
Acute Myeloid Leukemia can also be called what?
Acute Myelocytic Leukemia
which Leukemia is NOT typically treated with BMT?
CLL
which Leukemia has majority of older patients
CLL
Which Leukemia is associated with Philadelphia chromosome?
CML
what are 3 stages of CML?
chronic, accelerated, blast crisis
CLL is very RARE in who?
children
Chronic Myeloid Leukemia is also called what?
Chronic Myelogenous Leukemia
which Leukemia has radiation exposure (like atomic bomb or nuclear accident) as a high-risk factor?
CML
BMT is a _____ transplant
stem cell
BMT gives patient healthy ____ cells
hematopoietic cells
what are the different types of BMT? (3)
allogenic, syngenic, autologous
of the following, which is being described? - allogenic, syngenic, autologous
“stem cells come from a donor”
allogenic; best match is someone related to patient like a sibling
of the following, which is being described? - allogenic, syngenic, autologous
“stem cells come from identical twin”
syngenic; if patient DOES have an identical twin, this is best trt
of the following, which is being described? - allogenic, syngenic, autologous
“stem cells of own patient are removed, and given back after a treatment occurs”
autologous
