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Laura Nappi online course > Lymphomas > Flashcards

Lymphomas Flashcards

1
Q

Lymphatic system is part of the _____ system

A

immune

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2
Q

Lymphatic system is a network of ____ and ____

A

vessels and nodes

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3
Q

lymph nodes _____ foreign substances, and fight ______

A

filter foreign substances and fight infections

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4
Q

lymph _____ are networks that connect lymph nodes

A

lymph vessels connect lymph nodes

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5
Q

T/F: lymph nodes are located throughout the body

A

true

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6
Q

lymph fluid contain what blood cell?

A

WBC - to help fight infection

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7
Q

what are the 2 types of lymphocytes?

A

B and T

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8
Q

B or T cell lymphocytes destroy germs?

A

T cell *KILLER T

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9
Q

B or T cell lymphocytes create antibodies?

A

B cell *B = BODIES

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10
Q

the lymphatic system is made of cells called ____ which are type of ____ blood cell

A

lymphocytes; type of white blood cells

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11
Q

where are major sites of lymph tissue? (6)

A

spleen, bone marrow, thymus, adenoids, tonsils, and digestive tract

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12
Q

what do spleen and bone marrow have in common?

A

they both create lymphocytes

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13
Q

the ____ helps develop T cells

A

thymus

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14
Q

____ and ____ are a collection of lymph nodes in the throat

A

adenoids and tonsils

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15
Q

T/F: lymphoma can occur almost anywhere?

A

true

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16
Q

what are the 2 main types of lymphoma?

A

Hodgkins Lymphoma and Non-Hodgkins Lymphoma

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17
Q

what is the main histopathology of Hodgkin’s Lymphoma?

A

-cHL = Classic Hodgkin’s Lymphoma

-subtypes of Classic: Nodular sclerosis, Mixed cellularity, Lymphocyte rich, Lymphocyte depleted

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18
Q

What staging system do lymphomas use?

A

Ann Arbor

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19
Q

__ symptoms describe fever, night sweats, and 10% weight loss within six months

A

B symptoms

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20
Q

what is common spread for Hodgkins Lymphoma?

A

through the lymph system

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21
Q

is Hodgkins or Non-Hodgkins more likely to spread distantly?

A

NHL

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22
Q

where is 1st, 2nd, and 3rd distant place Hodgkins lymphoma would spread to?

A

Liver -> lungs -> bone

23
Q

Hodgkin’s lymphoma can (like NHL) can occur anywhere in body, however where is HL most common to start? Upper or Lower body

A

Upper - like chest, neck, or underarm area

24
Q

which has a predictable, contiguous (direct) spread? NHL or HL

A

HL

25
Q

contiguous spread means what?

A

direct spread/invasion

26
Q

Ann Arbor staging uses the ______ as a point of reference for staging

A

diaphragm

27
Q

according to Ann Arbor, stages 1 and 2 are limited to areas ___above/below___ the diaphragm

A

above

28
Q

according to Ann Arbor, stages 3 and 4 are limited to areas ___above/below___ the diaphragm

A

below

29
Q

which means there are NO symptoms - A or B

A

A; Asymptomatic

30
Q

which means THERE ARE symptoms - A or B

A

B

31
Q

what are examples of B symptoms

A

fever, night sweat, 10% weight loss

32
Q

if a patient has A or B symptoms, which is considered a worse prognosis?

A

B

33
Q

the ______ infection increases chance of getting Hodgkins Lymphoma

A

Epstein Barr Infection; EBV

34
Q

what is common chemo to treat Hodgkins Lymphoma?

A

ABVD (current gold standard); MOPP (original trt)

35
Q

which chemo combo is considered the current gold standard for treating Hodgkins lymphoma?

A

ABVD

36
Q

Hodgkin’s lymphoma is differentiated from Non-Hodgkin’s lymphoma how?

A

HL has Reed Sternberg cells (RS)
whereas NHL does NOT have RS cells

37
Q

________ are abnormal lymphocytes that are bi-nucleate (have 2 nucleus)

A

Reed Sternberg cells

38
Q

what is the most common type/histopathology of Hodgkin’s lymphoma?

A

Classic

39
Q

what is the most common subtype of Classic Hodgkin’s Lymphoma?

A

Nodular sclerosis (NS)

40
Q

what is common radiation field(s) used for Hodgkin’s Lymphoma?

A

Mantle field (treats lymph nodes in chest, neck, and axilla) or Inverted Y (treats lymph nodes in abdomen, pelvis, and spleen)

41
Q

if both mantle and inverted Y are to be treated, what do we call it?

A

Total Nodal Irradiation (TNI)

42
Q

what is the histopathology of NHL?

A

B cell lymphoma or T cell lymphoma

43
Q

NHL uses Ann Arbor staging with what classification?

A

Lugano classification

44
Q

what is common spread for NHL?

A

through lymph system

45
Q

which one, HL or NHL, spreads randomly and in no specific order?

A

NHL

46
Q

which lymphoma is likely to occur in the following areas -
lymph nodes, GI tract/peyers patches, and Waldeyer’s ring

A

NHL

47
Q

which lymphoma - HL or NHL, is more common in older patients?

A

NHL

48
Q

what chemo combo is used to treat NHL?

A

CHOP

49
Q

which NHL is most common T cell or B cell?

A

B cell

50
Q

NHL can be classified by their _________

A

aggressiveness

51
Q

describe spread of an indolent lymphoma -

A

spread and grow slowly, might not need treatment right away, fewer symptoms

52
Q

what is most common aggressive lymphoma?

A

diffuse large B cell lymphoma

53
Q

Lugano system is based 1-4 and an ___ is added when organs outside the lymphatic system are involved

A

E

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