Skeletal Flashcards

1
Q

skeletal system is made of ____ and _____

A

bone and cartilage

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2
Q

____ are the supportive framework or the human body

A

bones

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3
Q

_____ bone is the OUTER layer

A

Cortical

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4
Q

_____ bone is the INNER layer

A

Trabecular

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5
Q

_____ is the outer covering

A

Periosteum

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6
Q

___ = shaft of bone

A

Diaphysis * die with shaft in

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7
Q

____ = knoblike end of bone

A

Epiphysis * E = END

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8
Q

____ cavity = inner cavity of bone

A

medullary cavity

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9
Q

______ = lining

A

Endosteum

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10
Q

which part of bone contains bone marrow?

A

medullary cavity

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11
Q

bones start as _______

A

cartilage

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12
Q

____ helps form cartilage into bone!

A

calcium

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13
Q

_____ can stay at ends of bones and act as cushion, ie. our joints

A

cartilage

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14
Q

two cell types within a bone are what?

A

osteoclasts and osteoblast

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15
Q

osteo___ are cells that form new bones

A

osteoblasts

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16
Q

osteo___ are cells that dissolve old bone

A

osteoclasts

17
Q

tumors typically occur in areas of rapid growth, such as a ____ plate

18
Q

most common areas for bone tumors are ____ and _____. And why?

A

distal femur and proximal tibia - they have the largest growth plates

19
Q

majority of bone tumors ____are/are not____ metastatic

A

ARE metastatic; bone mets

20
Q

what primary bone tumor is most common?

A

osteosarcomas

21
Q

typically osteosarcomas occur in children, teens, and young adults however - which age group is most common

22
Q

osteosarcomas typically occur in what areas? (3)

A

femur, tibia, humerus

23
Q

osteoblastic, chondroblastic, and fibroblastic are all subtypes of what primary bone cancer?

A

osteosarcomas

24
Q

behind osteosarcomas, what primary bone cancer is most common in children, teens, and young adults?

A

Ewing sarcoma

25
ewing sarcoma of the __bone/soft tissue__ is most common type of ewing sarcoma
bone
26
which responds better to radiation? - ewing sarcomas or osteosarcoma?
ewing sarcoma
27
EOE stands for what?
Extra Osseous Ewing - sarcomas
28
____ occur in soft tissue around the bones
EOE (Extra Osseous Ewing)
29
PPNET stands for what?
Peripheral, Primitive, Neuroectodermal Tumors
30
most common site for a ewing tumor to occur is where?
pelvis, chest wall, or legs
31
osteosarcomas occur more commonly on ends (Epi) or bones or middle/shaft (Dia)? what about Ewing?
ends for osteosarcomas, middle/shaft for ewing
32
what cancer starts in cartilage cells
chondrosarcoma
33
what cancer starts in connective tissues?
MFH (Maligagnt Fibrous Histiocytoma)
34
Chondrosarcomas are graded __-__
1-3
35
MFH (Maligagnt Fibrous Histiocytoma) is also known as what?
UPS (high grade Undifferentiated Pleomorphic Sarcoma of bone)
36
overall, lymphatic spread is ___rare/common___ for bone tumors
rare
37
if bone tumor WERE to occur in lower limb/lower half of trunk, what nodes would be 1st? What about upper limb/upper half of trunk bone tumor? What about a skull or facial bone tumor?
lower -- femoral nodes upper -- axillary skull/face -- neck nodes
38
where do bone spread to 1st?
lung
39
**T/F: even though osteosarcoma is most common primary bone tumor, bone mets is still most common bone tumor overall
true