The Mess That Is Micro - X - Zoonotic Bacteria

Question 1

Anaplasma

Answer 1

Anaplasmosis - transmitted by Ixodes tick, which live on deer and mice.

Causes granulocytes with morulae in their cytoplasm. Present in south and west where Ixodes is found. Severe anemia and wasting in diseased cattle. Hematuria secondary to red blood cell lysis.

Question 2

Bartonella

Answer 2

Cat scratch disease - Gradual lymph node enlargement (axilla, groin, neck) after distal scratch or red-brown skin papule.
Bacillary angiomatosis - vascular proliferative disease involving mainly skin and other organs. Associated with HIV or immuno incompetence.

Question 3

Borrellia burgdorferi

Answer 3

Lyme disease - Ixodes ticks (live on deer and mcie)

Question 4

Borrelia recurrentis

Answer 4

Relapsing fever - louse, recurrent due to variable surface antigens.

Question 5

Brucella

Answer 5

Brucellosis / undulant fever - unpasteurized dairy.

Gram negative, small nonmotile coccoid rods. Transmitted by ingestion or direct contact with infected animals / abortion or premature birth, excreted in urine, milk, placenta. Non-caseating csarcoid like granulomas.

Treat with doxycycline

Question 6

Campylobacter

Answer 6

Bloody diarrhea. From puppies, livestock / fecal-oral, ingestion of undercooked meat.

Question 7

Chlamydophila psittaci

Answer 7

Psittacosis - parrot fever. Transmitted by parrots and other birds. Remember: Parrots like pistacios.

Question 8

Coxiella burnetti

Answer 8

Q fever. Aerosols of cattle / sheep amniotic fluid. Small gram negative, similar to Rickettsia. No arthropod vector. Tick feces and cattle placenta release spores that are inhaled as aerosles. Presents as pneumoniea.

Remember: Q fever is queer because it has no rash or vector and its causative organism can survive outside inits endospore form.

Question 9

Ehrlichia chaffeensis

Answer 9

Ehrlichiosis - lone star tick.

Monocytes with morulae (berry like inclusions in the cytoplasm). Rash is rare.

Question 10

Francisella tularensis

Answer 10

Tularemia - from ticks, rabbits, deer fly.

Facultative intracellular aerobic gram negative.

Question 11

Leptospira

Answer 11

Hawaiian surfers!

Causes Leptospirosis - Animal urine, contaminated water or soil, infected tissue.

Found in water contaminated with animal urine causing leptospirosis, flu-like sx, jaundice, photophobia with conjunctival suffusion (erythema without exudate). Prevalent among surfers and in the tropics (Hawaii).

Question 12

Weil disease

Answer 12

Icterohemorrhagic leptosporosis, severe form with jaundice and azotemia from liver and kidney dysfunction, fever, hemorrhage, anemia.

Question 13

Mycobacterium leprae

Answer 13

Leprosy - humans with lepromatous leprosy - armadillo

Question 14

Pasteurella multocida

Answer 14

Cellulitis, osteomyelitis - animal bites, cats, dogs

Question 15

Rickettsia prowazeii

Answer 15

Epidemic typhus - louse

Rash starts centrally and spreads out, sparing palsm and soles..

Question 16

Rickettsia rickettsii

Answer 16

Rocky Mt Spotted Fever - Dermacentor ticks

Occurs in North carolina and south atlantic states.

The bugs need CoA and NAD+ because they cannot synthesize ATP!!!

Rash typically starts at wrists and ankles and then spreads to trunk, palms, and soles.

Classic triad - headache, fever, rash / vasculitis.
PALMS AND SOLES seen in 
Coxsackie A - hand, foot, mouth disease
Rmsf 
Secondary syphilis

Question 17

Rickettsia typhi

Answer 17

Endemic typhus - Fleas

Rash starts centrally and spreads out, sparing palsm and soles..

Question 18

Yersinia pestis

Answer 18

Plague - Fleas - rats and prairie dogs are reservoirs.

Bacteria forms a biofilm that blocks digestive tract of the flea so that it keeps on biting you.