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USMLE GAME TIME > Pharmacology - Adverse Drug Reactions > Flashcards

Pharmacology - Adverse Drug Reactions Flashcards

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USMLE® Step 1 flashcards
1
Q

Coronary vasospasm

A

Cocaine, sumatriptan, ergot alkaloids

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2
Q

Cutaneous flushing

A

VANC - Vancomycin, Adenosine, Niacin, Ca2+ channel blockers

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3
Q

Dilated cardiomyopathy

A

Doxorubicin, daunorubicin

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4
Q

Torsades

A

Class III, Class IA, Antiarrhythmics, macrolides, antipsychotics, TCAs, fluoroquinolones

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5
Q

Adrenocortical insufficiency

A

HPA axis suppression secondary to glucocorticoid withdrawal

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6
Q

Hot flashes

A

Clomiphene (treats ovulation problems in women who want tobecome pregnant), tamoxifen

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7
Q

Hyperglycemia

A

Nick Takes Sweet Betafish to Court and Hides them as a Prank

Niacin, Tacrolimus, (Hyperglycemia), Beta-blockers, Corticosteroids, HCTZ, Protease inhibitors

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8
Q

Hypothyroidism

A

Lithium, amiodarone, sulfonamides

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9
Q

Acute cholestatic hepatitis with jaundice

A

Erythromycin

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10
Q

Diarrhea

A

Medicines acting erratically on colon

Metformin, acarbose, erythromycin, orlistat, colchicine

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11
Q

Hepatitis

A

INH

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12
Q

Focal to massive hepatic necrosis

A

Halothane, Amanita phalloides (death cap mushroom), VPA, Acetaminophen
HAVAc

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13
Q

Pancreatitis

A

As Val Did Alcohol at Court, she Died going Glp

Azathioprine, VPA, Didanosine, Alcohol, Corticosteroids, Diuretics, Glp-1

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14
Q

Pseudomembranous colitis

A

Clindamycin, ampicillin, cephalosporins

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15
Q

Agranulocytosis

A

Granny causes problems in dapper colorful clothes, methinks

Carbemazepine, propylthiouracil, dapsone, colchicine, clozaril, mehtimazole

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16
Q

Aplastic anemia

A

Proper Nuns Chlorinate the Car (a Mercedes Benz)

Propylthiouracil, NSAIDS, Chloramphenicol, Carbemazepine, Methimazole, Benzene

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17
Q

Direct coombs positive hemolytic anemia

A

Methyldopa (this is the alpha 2 agonist)

Penicillin

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18
Q

Gray baby syndrome

A

Chloramphenicol

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19
Q

Hemolysis in G6PD

A

INH, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

20
Q

Megaloblastic anemia

A

Phenytoin, Methotrexate, Sulfa drugs

Having a BLAST with PMS

21
Q

Thrombocytopenia

A

Heparin, cimetidine

22
Q

Thrombotic complications

A

OCPs

23
Q

Fat redistribution

A

Protease inhibitors, Glucocorticoids

24
Q

Gingival hyperplasia

A

Phenytoin, verapamil, cyclosporine, nifedipine

25
Q

Hyperuricemia (gout)

A

Pyrazinamide, Thiazides, Furosemide, Niacin, Cyclosporine, Topirimate

26
Q

Myopathy

A

Fibrates, Niacin, Colchicine, Hydroxychloroquine, Interferon-alpha, penicillamine, statins, glucocorticoids

27
Q

Osteoporosis

A

Corticosteroids, heparin

28
Q

Photosensitivity

A

Sulfonamides, Amiodarone, Tetracyclines, 5-FU

SAT For Photo

29
Q

Rash / SJS

A

Ethosuximide, Carbamazepine, Lamotrigine, Phenytoin, Phenobarbital, Allopurinol, Sulfa drugs, Penicillin

Stephen Johnson has epileptic Allergy to Sulfa Drugs and Penicillin

30
Q

SLE-like syndrome

A

Sulfa drugs, Hydralazine, INH, Procainamide, Phenytoin, Etanercept

Having Lupus is SHIPP-E

31
Q

Teeth discoloration

A

Tetracyclines

32
Q

Tendonitis, tendon rupture, cartilage damage

A

Fluoroquinolones

33
Q

Cinchonism (temporary deafness, ringing in ears, headache, dizziness, rash)

A

Quinidine, quinine

34
Q

Parkinson-like syndrome

A

Antipsychotics, reserpine, metoclopramide

Cogwheel rigidity of the ARM

35
Q

Seizures

A

INH, Buproprion, Imipenem/Cilastatin, tramadol, enflurane, metoclopramide

With seizures, I BITE My tongue.

36
Q

Tardive dyskinesia

A

Antipsychotics, metoclopromide

37
Q

Diabetes insipidus

A

Lithium, demeclocycline

38
Q

Fanconi syndrome

A

Expired tetracycline

39
Q

Hemorrhagic cystitis

A

Cyclophosphamide, ifosfamide (prevent by coadministering with mesna)

40
Q

Interstitial nephritis

A 
DRiPS N
Diuretics
Rifampin
Penicillins/beta lactam
Sulfonamides
NSAIDs

Dying pens suffer rightfully, nuffsaid.

41
Q

SIADH

A

Carbamazepine, Cyclophosphamide, SSRIs

Can’t concentrate Serum Sodium

42
Q

Dry cough

A

ACEI

43
Q

Pulmonary fibrosis

A

Bleomycin, Amiodarone, Busulfan, Methotrexate

But Sultan, Allmy Melons Bloomed (and gave me a coughing fit)

44
Q

Antimuscarinic

A

Atropine, TCAs, H1 blockers, antipsychotics

45
Q

Disulfiram like reaction

A

Metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st generation sulfonylureas

46
Q

Nephrotoxicity/ototoxicity

A

Aminoglycosides, vancomycin, loop diuretics, cisplatin

47
Q

Sulfa drugs

A

Probenecid, furosemide, acetazolamide, celecoxib, thiazides, sulfonamides, sulfasalazine, sulfonylureas

So basically the thiazides plus furosemide plus acetazolamide plus anything with a sulfa
And celecoxib and probenecid for… some reason…

USMLE GAME TIME (46 decks)

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