Repro - Pictures

Question 1

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Answer 1

Seminoma - note the fried eggs, maybe…

Question 2

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Answer 2

Schiller duval body - associated with yolk sac tumor

Question 3

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Answer 3

Schiller duval body - associated with yolk sac tumor

Question 4

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Answer 4

Reinke crystal associated with Leydig cell tumor

Question 5

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Answer 5

Schiller duval body

Schiller-Duval body is a distinctive perivascular structure seen in the endodermal sinus pattern of yolk sac tumor. It consists of a central vessel

Question 6

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Answer 6

Bowenoid papulosis - reddish papules associated with squamous cell carcinoma

Question 7

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Answer 7

Erythroplasia of Queyrat - associated with squamous cell carcinoma

Question 8

Erythroplakia

Answer 8

Erythroplakia (also termed erythroplasia)[1]:734 is a clinical term to describe any erythematous (red) area on a mucous membrane,[2] that cannot be attributed to any other pathology.[3]:805

The term erythroplasia was coined by Louis Queyrat to describe a precancerous red lesion of the penis.[4] This gave rise to the termerythoplasia of Queyrat.

Question 9

Bowen disease

Answer 9

Squamous cell carcinoma in situ

Question 10

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Answer 10

Choriocarcinoma

Choriocarcinoma is an uncommon testicular germ cell tumor that is usually seen as a component of mixed germ cell tumor.

Syncytiotrophoblastic and cytotrophoblastic elements

Question 11

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Answer 11

Embryonal carcinoma - malignant, hemorrhagic mass with necrosis - often glandular or papillary morphology

Question 12

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Answer 12

Invasive lobular carcinoma - orderly row of cells in indian file position - often bilateral with multiple lesions in the same location

Question 13

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Invasive lobular breast carcinoma - Indian file

Question 14

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Answer 14

Peau d’orange - breast skin resembles orange peel - dermal lymphatic invasion by breast carcinoma

Question 15

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Answer 15

Another example of a poorly differentiated invasive ductal carcinoma. The arrow points to a multinucleated tumor giant cell.

Question 16

Which breast cancer is most common?

Answer 16

Invasive dustal carcinoma - 76% of all breast cancers

It is also the worst and most invasive

Question 17

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Answer 17

What is the cell indicated by the arrow? Paget cell– large cells in epidermis with clear halo

Suggests underlying ductal carcinoma in situ

Question 18

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Answer 18

Paget cells - suggests underlying DCIS

Question 19

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Answer 19

Benign Phyllodes tumor of the breast - large bulky mass of connective tissue and cysts with leaf-like projections. Most common in the 6th decade. Some may be malignant.

Question 20

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Answer 20

Benign Phyllodes tumor of the breast - large bulky mass of connective tissue and cysts with leaf-like projections. Most common in the 6th decade. Some may be malignant.

Question 21

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Answer 21

Sarcoma botryoides (rhabdomyosarcoma variant)

Question 22

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Sarcoma botryoides (rhabdomyosarcoma variant) - occurs in girls < 4 vagina

Question 23

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Vagina clear cell adenocarcinoma

Question 24

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Answer 24

Krukenberg Tumor

Question 25

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Breast Comedocarcinoma, Medium Power Microscopic. The cells in the center of the ducts with comedocarcinoma are often necrotic and calcify Ductal, central necrosis

Question 26

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Answer 26

Comedocarcinoma

Question 27

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Answer 27

Brenner tumor of ovary

Question 28

struma ovarii

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Mature cystic teratoma that can also contain functional thyroid tissue and present as hyperthryoidism

Question 29

Meigs syndrome

Answer 29

Ovarian fibroma, ascites, hydrothorax (trio)

Question 30

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Answer 30

Mucinous cystadenoma

Question 31

Which cyst is associated with choriocarcinoma and moles?

Answer 31

Theca-lutein cyst

Question 32

What gene product does HPV 16 and HPV 18 produce?

Answer 32

E6 - inhibits p53 E7 - inhibits RB suppressor gene

Question 33

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Human papillomavirus-induced condylomatous infections. Biopsy of the condyloma shows koilocytes with perinuclear halos but lacking nuclear atypia.

Question 34

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Answer 34

Endometritis

Question 35

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Answer 35

Snowstorm on ultrasound - associated with complete mole

Question 36

How do you treat acute mastitis?

Answer 36

Dicloxacillin, usually staph aureus

Question 37

What drugs cause gynecomastia?

Answer 37

Some Dope drugs easily create awkward hairy DD knockers Spironolactone, Dope, Digitalis, Estrogen, Cimetidine, Alcohol, Heroin, Dopamine D2, Ketoconazole

Question 38

What are two tumor markers for prostatic adenocarcinoma?

Answer 38

PAP - prostatic acid phosphatase PSA - prostate specific antigen

Question 39

What is the most common testicular tumor?

Answer 39

Seminoma

Question 40

Increased placental ALP in a painless testicular enlargement should make one think...

Answer 40

Seminoma, possibly mixed embryonal carcinoma

Question 41

Increased hCG in a testicular tumor should make you think of

Answer 41

Choriocarcinoma, Teratoma, Embryonal carcinoma

Question 42

Hematogenous metastasis to lungs and brain in a testicular tumor should make you think of?

Answer 42

Choriocarcinoma

Question 43

Gynecomastia and hyperthyroidism in a testicular tumor should make you think of?

Answer 43

Choriocarcinoma

Question 44

Malignant hemorrhagic painful testicular tumor should make you think of?

Answer 44

Embryonal carcinoma

Question 45

Most common testicular cancer in older men?

Answer 45

Testicular lymphoma