Endocrine - Signalling pathways for endocrine hormones

Question 1

cAMP

Answer 1

FLAT ChAMP

FSH, LH, ACTH, TSH, CRH, hCG, ADH (V2 receptor), MSH, PTH

Also calcitonin, GHRH, glucagon

Question 2

cGMP

Answer 2

ANP, NO (EDRF) - vasodilators

Question 3

IP3

Answer 3

GOAT HAG with a hairlIP is queer

GnRH, Oxytocin, ADH (V1), TRH, Histamine (H1), Ang II, Gastrin

Question 4

Steroid receptor

Answer 4

Estrogen, testosterone, cortisol, aldosterone, progesterone

and the ones that don’t quite fit vitamin D and T3/T4

Question 5

Intrinsic tyrosine kinase, MAP kinase pathway

Answer 5

Insulin, IGF-1, FGF, PDGF, EGF

Question 6

Receptor associated tyrosine kinase (JAK-STAT)

Answer 6

Prolactin, immunomodulators (cytokines IL-2, IL6, IL8, IFN), GH
acidophiles and cytokines…

Question 7

What does insulin signal through?

Answer 7

Intrinsic tyrosine kinase - MAP kinase pathway

Question 8

What does glucagon signal through?

Answer 8

cAMP

Question 9

What does Ang II signal through?

Answer 9

IP3

Question 10

What does gastrin signal through?

Answer 10

IP3

Question 11

What does NO signal through?

Answer 11

cGMP

Question 12

What does T3/T4 signal through

Answer 12

Steroid rceptor pathway

Question 13

What does PTH signal through?

Answer 13

cAMP

Question 14

What does FSH and LH signal through?

Answer 14

cAMP

Question 15

What does V1 signal through? How about V2?

Answer 15

V1 - IP3, V2 - cAMP