Pharmacology - Antidotes Flashcards by Christina W

Q

AChE inhibitors

A

Atropine followed by pralidoxime

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Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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Q

Organophosphates

A

Atropine followed by pralidoxime

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Q

Amphetamines

A

NH4Cl (acidify the urine)

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Q

Antimuscarinic, anticholinergic agents

A

Physostigmine salicylate, controls hyperthermia

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Q

Benzodiazepines

A

Flumenazil

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Q

Beta blockers

A

Glucagon

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Q

Carbon monoxide

A

100 percent oxygen or hyperbaric o2

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Q

Copper

A

Penicillamine

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Q

Arsenic

A

Penicillamine

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Q

Gold

A

Penicillamine

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Q

Cyanide

A

Nitrite and thiosulfate or hydroxocobalamin

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Q

Digitalis

A

Anti digitalis fab fragments

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Q

Heparin

A

Protamine sulfate

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Q

Iron

A

Deferoxamine, deferasirox

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Q

Lead

A

EDTA
Dimercaprol
Succimer
Penicillamine

Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

Q

Methanol or ethylene glycol

A

Fomepizol > ethanol

Dialysis

Q

Methemoglobin

A

Methylene blue

Vitamin c

Q

Opioids

A

Naloxone

Q

Salicylates

A

Sodium bicarb to alkalinize urine

Then dialysis

Q

Tricyclic antidepressants

A

Sodium bicarb for plasma alkalinization

Q

Tissue plasminogen activator
Streptokinase
Urokinase

A

Aminocaproic acid

Q

Warfarin

A

Vitamin k

Plasma, if active bleeding