The limbic system Flashcards
What is the limbic system involved in
Pleasure
Pain
Learning
Memory
Where are the nuclei of the limbic system located
Medial aspect of frontal, parietal and temporal lobes
In simple organisms, what systems is the limbic system connected to
Olfactory and memory
What makes up the limbic system in the frontal and parietal lobes
Orbito-frontal cortex
Cingulate cortex
What makes up the limbic system in the medial temporal lobe
Parahippocampal cortex
What is the main blood supply to the limbic system
Anterior and posterior cerebral artery
What blood vessel supplies the tip of temporal lobe and orbital cortex in some people
Middle cerebral artery
When is the anterior cingulate cortex activated
Pain and depression
What does the caudal anterior cingulate register
The quality of pain (how bad on scale of 1-10)
What does the rostral anterior cingulate register
What actions to take to deal with the pain
Where does nociceptive information travel up
Lateral spinothalamic tract
Where does nociceptive information go once travelled up lateral spinothalamic tract
Parabrachial nucleus
Amygdala
Anterior thalamic nucleus
Anterior cingulate cortex and insula
What area of the brain is responsible for processing the unpleasantness of the pain and its emotional consequences
Anterior cingulate cortex and insula
What area of the brain is activated to ‘do something’ about the pain
Prefrontal cortex
What is a cingulotomy
Procedure of cutting the cingulate fibres to disrupt the fibres passing rostro-caudally reducing the emotional distress of pain
What % of people report improvement post cingulotomoy?
What % didn’t need painkillers anymore
72% report improvement
50% report reduction for need of painkillers
What is the orbitofrontal cortex involved in
Reacted to an anticipated threat (eg actions to avoid more pain)
How does the behaviours associated with orbitofrontal cortex differ in people with OCD
- In a difficult decision, person may be unable to respond to threat and ‘freeze’
- Prolonged pressure to make these choices00> OCD
When does the posterior cingulate cortex show activity
When recalling memories with emotional significance
Where do the parahippocampal gyrus lie
Medially and inferiorly on temporal lobe
What is the parahippocampal gyrus involved in primarily
Acquisition of new memories
What 2 structures are the subcortical parts of the limbic system
Hippocampus and amygdala