THE IMPORTANT HORMONES OF THE ADRENAL GLANDS(CORTISOL) Flashcards
This is often called as “stress hormones”
Cortisol
This is the process of the body is utilizing glucose at a faster rate so in return kakain ka.
Stress eating
Identify if the process “Increases” or “Decreases” in Cortisol
- Lipolysis
Increased
Identify if the process “Increases” or “Decreases” in Cortisol
- Protein catabolism
Increased
Identify if the process “Increases” or “Decreases” in Cortisol
- Protein synthesis
Decreased
Identify if the process “Increases” or “Decreases” in Cortisol:
- Antibody formation
Decreased
Under cortisol, the infection will spread because?
The inflammatory response is suppressed
What secretes the corticotrophin releasing hormone?
hypothalamus
What do hypothalamus secretes under the regulation of cortisol?
corticotrophin releasing hormone
What do the Anterior Pituitary secretes?
adrenocorticotropic hormone
What controls the Cortisol production feedback loop?
adrenocorticotropic hormone
What do low and elevated levels of plasma Cortisol mean?
- Low levels of plasma Cortisol promote ACTH release
- Elevated levels of plasma Cortisol inhibit ACTH release
What is the REFERENCE RANGES TOTAL CORTISOL?
A. 8AM : 5-23ug/dL (Higher)
B. 4PM: 3-16 ug/dL
What is the clinical significance of Cortisol?
HYPERCORTISOLISM
HYPOCORTICOLISM
What are the types of Hypercortisolism?
Primary Hypercortisolism
Secondary Hypercortisolism
Primary Hypercortisolism is primalrily caused by?
Adrenal adenoma or carcinoma
Exogenous administration of Cortisol
Cushing syndrome
Secondary Hypercortisolism is primarily caused by?
Excessive production of ACTH due to pituitary tumor
Ectopic production of ACTH by nonendocrine tumor
What are the types of Hypocortisolism?
Primary hypocortisolism
Secondary hypocortisolism
Primary hypocortisolism is caused by?
Atrophy of Adrenal gland,
autoimmune disease,
tuberculosis,
prolonged high-dosage Cortisol therapy
What causes Secondary hypocortisolism?
Pituitary hypofunction
What method is used under the laboratory assay under Cortisol?
Dexamethasone Suppression
Exogenous steroid to suppress innate cortisol production
Dexamethasone Suppression
What is “normal” in Dexamethasone Suppression?
decreased cortisol (suppressed)
What is identified as “Cushing’s syndrome” under Dexamethasone suppression?
Increased cortisol (not suppressed)
A test for cortisol concentration is done ______ to the administration of the steroid and after the administration
prior
