HORMONES OF ADRENAL MEDULLA Flashcards
What is the hormones of the Adrenal Medulla?
Catecholamines
Catecholamines is synthesized from?
Tyrosine
This hormones is synthesized from tyrosine
CATECHOLAMINES
This is inside the chromaffin cells
Tyrosine
This serves as a precursor for the Catecholamines?
Tyrosine
What are the 3 important Catecholamines?
Epinephrine
norepinephrine and;
dopamine
This is the metabolite of dopamine
Homovanillic acid (HVA
Epinephrine and Norepinephrine metabolite
Metanephrines/Normetanephrines and Vanillylmandelic acid (VMA)
Metanephrines/Normetanephrines will further cleave to become the final metabolite of Epinephrine and Norepinephrine called __________________?
Vanillylmandelic acid
This mobilizes energy stores by converting glycogen to glucose which allows the voluntary muscle exertion, and pain.
Epinephrine
This function as a neurotransmitter affecting the vascular smooth muscle and hear
Norepinephrine
Norepinephrine functions as a neurotransmitter affecting the?
vascular smooth muscle and heart
What releases the norepinephrine?
postganglionic sympathetic nerves
Functions as a neurotransmitter in the brain affecting the vascular system
Dopamine
The Dopamine functions as a neurotransmitter in the brain affecting the?
Vascular system
This is a tumor in adrenal medulla: excess epinephrine. Causes hypertension, headache and Increased heart rate
Pheochromocytoma
This is a malignant tumor of adrenal medulla seen in children.
Abdominal mass
Neuroblastoma
best screening test for pheochromocytoma because the metabolites of epinephrine and norepinephrine can be excreted out in the urine
Urinary metanephrine
What is the reason why urinary metanephrine is the best screening test for pheochromocytoma?
because the metabolites of epinephrine and norepinephrine can be excreted out in the urine
In the laboratory assay of Catecholamines what are the specimens used?
Plasma and/or urine
Urinary metanephrine
Urinary VMA and HVA
Transcribe HVA and VMA
Homovanillic acid (HVA)
Vanillylmandelic acid (VMA)