HORMONES OF ADRENAL MEDULLA Flashcards

1
Q

What is the hormones of the Adrenal Medulla?

A

Catecholamines

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2
Q

Catecholamines is synthesized from?

A

Tyrosine

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3
Q

This hormones is synthesized from tyrosine

A

CATECHOLAMINES

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4
Q

This is inside the chromaffin cells

A

Tyrosine

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5
Q

This serves as a precursor for the Catecholamines?

A

Tyrosine

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6
Q

What are the 3 important Catecholamines?

A

Epinephrine
norepinephrine and;
dopamine

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7
Q

This is the metabolite of dopamine

A

Homovanillic acid (HVA

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8
Q

Epinephrine and Norepinephrine metabolite

A

Metanephrines/Normetanephrines and Vanillylmandelic acid (VMA)

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9
Q

Metanephrines/Normetanephrines will further cleave to become the final metabolite of Epinephrine and Norepinephrine called __________________?

A

Vanillylmandelic acid

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10
Q

This mobilizes energy stores by converting glycogen to glucose which allows the voluntary muscle exertion, and pain.

A

Epinephrine

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11
Q

This function as a neurotransmitter affecting the vascular smooth muscle and hear

A

Norepinephrine

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12
Q

Norepinephrine functions as a neurotransmitter affecting the?

A

vascular smooth muscle and heart

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13
Q

What releases the norepinephrine?

A

postganglionic sympathetic nerves

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14
Q

Functions as a neurotransmitter in the brain affecting the vascular system

A

Dopamine

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15
Q

The Dopamine functions as a neurotransmitter in the brain affecting the?

A

Vascular system

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16
Q

This is a tumor in adrenal medulla: excess epinephrine. Causes hypertension, headache and Increased heart rate

A

Pheochromocytoma

17
Q

This is a malignant tumor of adrenal medulla seen in children.

Abdominal mass

A

Neuroblastoma

18
Q

best screening test for pheochromocytoma because the metabolites of epinephrine and norepinephrine can be excreted out in the urine

A

Urinary metanephrine

19
Q

What is the reason why urinary metanephrine is the best screening test for pheochromocytoma?

A

because the metabolites of epinephrine and norepinephrine can be excreted out in the urine

20
Q

In the laboratory assay of Catecholamines what are the specimens used?

A

 Plasma and/or urine
 Urinary metanephrine
 Urinary VMA and HVA

21
Q

Transcribe HVA and VMA

A

Homovanillic acid (HVA)
Vanillylmandelic acid (VMA)