PARATHYROID GLAND Flashcards

1
Q

Where is the parathyroid gland located?

A

posterior of the thyroid gland

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2
Q

How many parathyroid gland are there?

A

4

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3
Q

What are the 2 types of cells that composes the PTG?

A

a. Chief cells
b. Oxyphil cells

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4
Q

TRUE OR FALSE:
Chief cells and Oxyphil cells has the same functionality

A

TRUE

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5
Q

Between the 2 types of cells that composes the PTG, which is more dominant?

A

Chief cells

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6
Q

What are the functions of Chief cells and Oxyphil cells?

A
  1. Synthesize hormones that are secreted by the PTG.
  2. They are responsible for storing PTH.
  3. They are responsible for the secretion of PTH
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7
Q

What are the 3 organs that PTG affects?

A

Kidney
Intestines
Bones

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8
Q

This refers to the abnormal elevation of PTH?

A

Hyperparathyroidism q

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9
Q

What do hypercalcemia promotes?

A

Kidney stone formation

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10
Q

This promotes kidney stone formation

A

Hypercalcemia

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11
Q

What are the signs and symptoms of Hypercalcemia?

A
  1. Fatigue,
  2. personality changes
  3. lethargy
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12
Q

Most cases of primary hyperparathyroidism is caused by what?

A

Tumor
Cancer
Adenoma

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13
Q

This overstimulates the gland releasing PTH which will cause abnormal elevation of Calcium in the blood

A

Cancer

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14
Q

80% due to___________________?

A

parathyroid adenoma

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15
Q

In P. Hyperparathyroidism, __________ due to parathyroid adenoma?

A

80%

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16
Q

Primary hyperparathyroidism is seen in patients with?

A

Kidney and bone disease

17
Q

What does it mean by Hypercalcemic state?

A

High PTH and high Calcium level

18
Q

High PTH and high Calcium level

A

Hypercalcemic state

19
Q

This is due to external factors s like Vitamin D deficiency Lack of Calcium absorption, or Low dietary states

A

Secondary hyperparathyroidism

20
Q

Secondary hyperparathyroidism is seen in patients with?

A

chronic renal failure

21
Q

Describe the PTH and Calcium level of Secondary hyperparathyroidism

A

High PTH however the Calcium level is low

22
Q

What are the 2 types of Hyperparathyroidism?

A

Primary hyperparathyroidism
Secondary hyperparathyroidism

23
Q

This is due to injury of the PTG, and inborn errors of metabolism

A

HYPOPARATHYROIDISM

24
Q

The decrease in Calcium concentration may cause the correlated conditions?

A

Tetany and altered neuromuscular activity

25
Q

A deficiency of blood calcium causes __________________ to ____________and produce action potentials spontaneously?

A

neurons and muscle fibers
depolarize

26
Q

What are the SIGNS AND SYMPTOMS OF HYPOCALCEMIA ASSOCIATED WITH TETANUS AND ALTERED NEUROMUSCULAR ACTIVITY?

A

 Twitches (Involuntary muscle movement)
 spasms and;
 tetany of skeletal muscle