AMS Flashcards
What is the systematic name of amylase?
E.C.3.2.1.1
What is the chemical name of AMS?
a-1,4-glucan-4-glucanohydrolase
What does the amylase hydrolyze?
1,4-a-glucocidic linkage in
polysaccharides.
The only enzyme that can be found in the urine
Amylase
What is the MW of amylase?
45,000
What is the optimum pH of Amylase?
Optimum pH: 6.9 – 7.0 in serum
Without this, amylase cannot perform its duty.
Calcium
Where is the amylase secreted in the pancreas?
Acinar cells
Responsible in the hydrolysis of starch from the food
that we eat.
Salivary gland
Small amount of Amylase can be found
SEMINAL FLUID, TESTIS, OVARIES, FALLOPIAN TUBES, STRIATED
MUSCLE, LUNGS AND ADIPOSE TISSUE
first milk produced by a lactating
mother
Colostrum
it hydrolyses the 1,4-a-glucocidic
linkage to form the following 3 products:
a. Glucose
b. Maltose
c. Dextrin
What are the reactions catalyzed by amylase?
Starch digestion
Splits complex CHO made up of a-D glucose units
Inhibited by monoclonal antibody
Inhibited by protein isolated from wheat
Accounts for the 2/3 of the Amylase activity in
the normal serum
S-type Isoamylase
Fastest migrating in electrophoresis
S1 isoamylase
Inhibited by monoclonal antibody
Not inhibited by protein isolated from wheat
P-type Isoamylase (Pancreas)
What is the most common fraction type of isoenzyme?
P2, S1 AND S2